Enhanced Insulin Sensitivity and Body Composition Following 12wk Dietary and Exercise Interventions in Obese Subjects

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S243
Author(s):  
Paul J. Arciero ◽  
Roger M. Pressman ◽  
Bradley C. Nindl ◽  
Matthew D. Vukovich ◽  
Michael J. Ormsbee ◽  
...  
2004 ◽  
Vol 36 (Supplement) ◽  
pp. S243
Author(s):  
Paul J. Arciero ◽  
Roger M. Pressman ◽  
Bradley C. Nindl ◽  
Matthew D. Vukovich ◽  
Michael J. Ormsbee ◽  
...  

2017 ◽  
Vol 8 (4) ◽  
pp. 557-562 ◽  
Author(s):  
J. Most ◽  
G.H. Goossens ◽  
D. Reijnders ◽  
E.E. Canfora ◽  
J. Penders ◽  
...  

Gut microbiota composition may play an important role in the development of obesity-related comorbidities. However, only few studies have investigated gender-differences in microbiota composition and gender-specific associations between microbiota or microbial products and insulin sensitivity. Insulin sensitivity (hyperinsulinemic-euglycemic clamp), body composition (dual energy X-ray absorptiometry), substrate oxidation (indirect calorimetry), systemic inflammatory markers and microbiota composition (PCR) were determined in male (n=15) and female (n=14) overweight and obese subjects. Bacteroidetes/Firmicutes-ratio was higher in men than in women (P=0.001). Bacteroidetes/Firmicutes-ratio was inversely related to peripheral insulin sensitivity only in men (men: P=0.003, women: P=0.882). This association between Bacteroidetes/Firmicutes-ratio and peripheral insulin sensitivity did not change after adjustment for dietary fibre and saturated fat intake, body composition, fat oxidation and markers of inflammation. Bacteroidetes/Firmicutes-ratio was not associated with hepatic insulin sensitivity. Men and women differ in microbiota composition and its impact on insulin sensitivity, implying that women might be less sensitive to gut microbiota-induced metabolic aberrations than men. This trial was registered at clinicaltrials.gov as NCT02381145.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Diane I. Lopez ◽  
Lauren Chacon ◽  
Denise Vasquez ◽  
Louis D. Brown

Abstract Background Hispanic immigrants continue to experience higher rates of overweight and obesity compared to their non-Hispanic counterparts. Acculturation may contribute to unhealthy weight gain among immigrant populations by shifting dietary patterns from high fruit and vegetable consumption to unhealthier high fat diets. Healthy Fit, a culturally tailored community health worker (CHW) intervention, aims to reduce obesity related outcomes by providing physical activity and nutrition education and resources in a low-income Hispanic population. This study aims to evaluate outcomes of Healthy Fit participants and examine changes in body composition in relation to level of acculturation at baseline and follow-up. Method In this longitudinal observational study, CHWs recruited 514 participants from community events and agencies serving low-income Hispanic populations in El Paso, Texas from 2015 to 2016. Following an in-person health screening, eligible participants received nutrition and physical activity education guided by fotonovelas, comic-like educational books. Telephone follow-ups made at 1, 3, and 6 months by CHWs encouraged follow-through on referrals. 288 participants completed the screening again during the 12-month follow-up. Results The sample was predominantly Hispanic (96%), female (82%), uninsured (79%), had a household income of less than $19,999 (70%), foreign-born (79%), preferred Spanish (86%) and few rated themselves as good or excellent for English proficiency (27%). Overall, Healthy Fit participants significantly improved (i.e., decreased) BFP by 0.71% (t = 2.47, p = 0.01) but not BMI (b = .01, t = − 0.14, p = .89). Contrary to expectations, acculturation was not associated with lower BMI (b = 0.09, p = 0.84) or BFP (b = 0.13, p = 0.85) at baseline. However, acculturation predicted changes in both BMI (b = 0.30, p = 0.03) and BFP (b = 1.33, p = 0 .01) from baseline to follow-up. Specifically, the low acculturation group improved in body composition measures over time and the high acculturation group did not improve in either measure. Conclusion Findings suggest Healthy Fit was most effective among less acculturated individuals. The influence of acculturation on the efficacy of nutrition and exercise interventions suggests that Hispanics should not be treated as a homogenous subgroup.


Diabetes Care ◽  
2012 ◽  
Vol 35 (6) ◽  
pp. 1316-1321 ◽  
Author(s):  
C. Conte ◽  
E. Fabbrini ◽  
M. Kars ◽  
B. Mittendorfer ◽  
B. W. Patterson ◽  
...  

2011 ◽  
Vol 96 (11) ◽  
pp. E1843-E1847 ◽  
Author(s):  
M. K. Svensson ◽  
P.-A. Jansson ◽  
A. L. Persson ◽  
M. Sjöstrand ◽  
J. W. Eriksson

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