Definition of a Region of Loss of Heterozygosity at Chromosome 11q23.3-25 in Head and Neck Squamous Cell Carcinoma Using Laser Capture Microdissection Technique

2004 ◽  
Vol 13 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Dongfeng Tan ◽  
Sam Wiseman ◽  
Youtai Zhou ◽  
Qiang Li ◽  
Pamela Ward ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Laser Capture Microdissection ◽  
Neck Squamous Cell Carcinoma ◽  
Definition Of ◽  
Laser Capture

scholarly journals Loss of heterozygosity in FANCG, FANCF and BRIP1 from head and neck squamous cell carcinoma of the oral cavity

2017 ◽  
Vol 50 (6) ◽  
pp. 2207-2220 ◽  
Author(s):  
Christin Türke ◽  
Susanne Horn ◽  
Carola Petto ◽  
Dirk Labudde ◽  
Günter Lauer ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma

scholarly journals Role of Extracapsular Nodal Spread and Surgical Margin Status in defining High-risk Head and Neck Squamous Cell Carcinoma and its Treatment Intensity

2017 ◽  
Vol 8 (2) ◽  
pp. 76-83
Author(s):  
Volkert B Wreesmann
Keyword(s):  
Squamous Cell Carcinoma ◽  
High Risk ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Surgical Margin ◽  
Neck Squamous Cell Carcinoma ◽  
Nodal Spread ◽  
Definition Of

ABSTRACT High-risk head and neck squamous cell carcinoma (HNSCC) includes an ill-defined collection of tumors that share an extremely poor outcome after seemingly appropriate multimodality treatment. Accumulating evidence suggests that extracapsular nodal spread and suboptimal surgical margins may be markers of high-risk HNSCC, but their utility is limited by ambiguous pathological criteria and unsatisfactory establishment of independent prognostic value. Inaccurate definition of high-risk HNSCC continues to obscure the scientific basis of treatment intensification protocols that have been proposed for high-risk HNSCC. Recent studies propose a more objective definition of clinically relevant extracapsular nodal spread (ECS) and surgical margins, which may contribute to improved staging and treatment selection. How to cite this article Wreesmann VB. Role of Extracapsular Nodal Spread and Surgical Margin Status in defining High-risk Head and Neck Squamous Cell Carcinoma and its Treatment Intensity. Int J Head Neck Surg 2017;8(2):76-83.

scholarly journals Prognostic implications of loss of heterozygosity at 8p21 and 9p21 in head and neck squamous cell carcinoma

2004 ◽  
Vol 111 (2) ◽  
pp. 206-212 ◽  
Author(s):  
Steven W. Coon ◽  
Adnan T. Savera ◽  
Richard J. Zarbo ◽  
Michael S. Benninger ◽  
Gary A. Chase ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Prognostic Implications

scholarly journals Loss of heterozygosity of chromosome 9p21 in head and neck squamous cell carcinoma.

1997 ◽  
Vol 23 (1) ◽  
pp. 165-172
Author(s):  
Kiyoto SHIGA ◽  
Junkichi YOKOYAMA ◽  
Shigeru SAIJO ◽  
Taeko MIYAGI ◽  
Kazuto MATSUURA ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Chromosome 9P21
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