QS6: Developing The Psychosocial Growth Chart: Prospective Longitudinal Psychosocial Functioning Of Children With Craniofacial Anomalies

Abstract Background Bipolar disorders (BD) belong to the most severe mental disorders, characterized by an early onset, predominantly recurrent/chronic course and poor psychosocial functioning. Many patients with BD experience substantial symptomatology months or even years before full BD manifestation. Adequate diagnosis and treatment is often delayed, which is associated with a worse outcome. This study aims to prospectively evaluate and improve early recognition and intervention strategies for persons at-risk for BD. Methods and Results Early-BipoLife is a prospective-longitudinal cohort study of 1419 participants (aged 15-35 years) with at least five waves of assessment over a period of at least 2 years (baseline, 6, 12, 18 and 24 months). A research consortium of ten university and teaching hospitals across Germany conducts this study. The following risk groups (RGs) were recruited: RG I: help-seeking youth & young adults consulting early recognition centres/facilities presenting ≥1 of the proposed risk factors for BD, RG II: in-/outpatients with unipolar depressive syndrome, and RG III: in-/ outpatients with attention-deficit/hyperactivity disorder (ADHD). The reference cohort was selected from the German representative IMAGEN cohort. Over the study period, the natural course of risk and resilience factors, early symptoms of BD and changes of symptom severity (including conversion to manifest BD) are observed. Psychometric properties of recently developed, structured instruments on potential risk factors for conversion to BD and subsyndromal symptomatology (Bipolar Prodrome Symptom Scale, Bipolar at-risk criteria, EPI bipolar ) and biomarkers that potentially improve prediction are investigated. Moreover, actual treatment recommendations are monitored in the participating specialized services and compared to recently postulated clinical categorization and treatment guidance in the field of early BD. Conclusion Findings from this study will contribute to an improved knowledge about the natural course of BD, from the onset of first noticeable symptoms (precursors) to fully developed BD, and about mechanisms of conversion from subthreshold to manifest BD. Moreover, these generated data will provide information for the development of evidence-based guidelines for early-targeted detection and preventive intervention for people at risk for BD.

Download Full-text

Physical and Psychosocial Recovery in the Year After Primary Treatment of Breast Cancer

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.8043 ◽

2011 ◽

Vol 29 (9) ◽

pp. 1101-1109 ◽

Cited By ~ 143

Author(s):

Patricia A. Ganz ◽

Lorna Kwan ◽

Annette L. Stanton ◽

Julienne E. Bower ◽

Thomas R. Belin

Keyword(s):

Breast Cancer ◽

Adjuvant Chemotherapy ◽

Psychosocial Functioning ◽

Breast Cancer Survivors ◽

Primary Treatment ◽

Physical Symptoms ◽

Self Report ◽

Chemotherapy Treatment ◽

Sf 36 ◽

Prospective Longitudinal

Purpose The 2000 National Institutes of Health Consensus Conference on Adjuvant Therapy of Breast Cancer recommended chemotherapy for all women with invasive cancer greater than 1 centimeter. Studies of long-term breast cancer survivors have found poorer quality of life (QOL) in women who received adjuvant chemotherapy. The aim of this article is to characterize physical and psychosocial recovery as a function of chemotherapy receipt in the year after medical treatment completion. Patients and Methods Prospective longitudinal survey data (RAND SF-36 and Breast Cancer Prevention Trial [BCPT] Symptom Scales) collected from 558 women with breast cancer enrolled on the Moving Beyond Cancer (MBC) psychoeducational intervention trial were compared according to receipt of chemotherapy. MBC study enrollment occurred within 4 weeks after the end of primary treatment (eg, surgery, chemotherapy, radiation). Self-report questionnaire data collected at enrollment and at 2, 6, and 12 months thereafter were examined, controlling for intervention and with propensity score adjustment for imbalance of covariates. Outcome analyses were carried out by fitting linear mixed models by using SAS PROC MIXED. Results Longitudinal SF-36 scale scores did not differ by chemotherapy treatment exposure, and both groups improved significantly (P < .01) in the year after primary treatment ended. However, adjuvant chemotherapy treatment was associated with significantly more severe physical symptoms, including musculoskeletal pain (P = .01), vaginal problems (P < .01), weight problems (P = .01), and nausea (P = .03). Conclusion Physical and psychosocial functioning improved significantly after breast cancer treatment, independent of receipt of adjuvant chemotherapy. Women who received chemotherapy experienced more severe and persistent physical symptoms that should be more effectively managed as part of survivorship care.

Download Full-text

Improving early recognition and intervention in people at increased risk for the development of bipolar disorder - Study protocol of a prospective-longitudinal, naturalistic cohort study (Early-BipoLife)

10.21203/rs.2.19667/v2 ◽

2020 ◽

Author(s):

Andrea Pfennig ◽

Karolina Leopold ◽

Julia Martini ◽

Anne Boehme ◽

Martin Lambert ◽

...

Keyword(s):

Risk Factors ◽

At Risk ◽

Cohort Study ◽

Psychosocial Functioning ◽

Preventive Intervention ◽

Early Recognition ◽

Natural Course ◽

Teaching Hospitals ◽

Increased Risk ◽

Prospective Longitudinal

Abstract Background Bipolar disorders (BD) belong to the most severe mental disorders, characterized by an early onset and recurrent, severe episodes or a chronic course with poor psychosocial functioning in a proportion of patients. Many patients with BD experience substantial symptomatology months or even years before full BD manifestation. Adequate diagnosis and treatment is often delayed, which is associated with a worse outcome. This study aims to prospectively evaluate and improve early recognition and intervention strategies for persons at-risk for BD. Methods and Results Early-BipoLife is a prospective-longitudinal cohort study of 1,419 participants (aged 15-35 years) with at least five waves of assessment over a period of at least 2 years (baseline, 6, 12, 18 and 24 months). A research consortium of ten university and teaching hospitals across Germany conducts this study. The following risk groups (RGs) were recruited: RG I: help-seeking youth & young adults consulting early recognition centres/facilities presenting ≥1 of the proposed risk factors for BD, RG II: in-/outpatients with unipolar depressive syndrome, and RG III: in-/ outpatients with attention-deficit/hyperactivity disorder (ADHD). The reference cohort was selected from the German representative IMAGEN cohort. Over the study period, the natural course of risk and resilience factors, early symptoms of BD and changes of symptom severity (including conversion to manifest BD) are observed. Psychometric properties of recently developed, structured instruments on potential risk factors for conversion to BD and subsyndromal symptomatology (Bipolar Prodrome Symptom Scale, Bipolar at-risk criteria, EPI bipolar ) and biomarkers that potentially improve prediction are investigated. Moreover, actual treatment recommendations are monitored in the participating specialized services and compared to recently postulated clinical categorization and treatment guidance in the field of early BD. Conclusion Findings from this study will contribute to an improved knowledge about the natural course of BD, from the onset of first noticeable symptoms (precursors) to fully developed BD, and about mechanisms of conversion from subthreshold to manifest BD. Moreover, these generated data will provide information for the development of evidence-based guidelines for early-targeted detection and preventive intervention for people at risk for BD.

Download Full-text

Cannabis use and psychosocial functioning: evidence from prospective longitudinal studies

Current Opinion in Psychology ◽

10.1016/j.copsyc.2020.07.001 ◽

2021 ◽

Vol 38 ◽

pp. 19-24

Author(s):

Madeline H Meier

Keyword(s):

Longitudinal Studies ◽

Psychosocial Functioning ◽

Cannabis Use ◽

Prospective Longitudinal

Download Full-text

Effect of Parental English Proficiency on Psychosocial Functioning in Children with Craniofacial Anomalies

Plastic & Reconstructive Surgery ◽

10.1097/prs.0000000000006577 ◽

2020 ◽

Vol 145 (3) ◽

pp. 764-773 ◽

Cited By ~ 1

Author(s):

Fransia S. De Leon ◽

Miles J. Pfaff ◽

Elizabeth J. Volpicelli ◽

Hi’ilani M. K. Potemra ◽

Johnny Lin ◽

...

Keyword(s):

Psychosocial Functioning ◽

English Proficiency ◽

Craniofacial Anomalies

Download Full-text

Psychosocial Functioning of Children with Craniofacial Anomalies Before and During Covid-19

Journal of the American College of Surgeons ◽

10.1016/j.jamcollsurg.2021.08.441 ◽

2021 ◽

Vol 233 (5) ◽

pp. e163-e164

Author(s):

Kelly X. Huang ◽

Michelle K. Oberoi ◽

Vivian J. Hu ◽

Rachel M. Caprini ◽

Sri Harshini Malapati ◽

...

Keyword(s):

Psychosocial Functioning ◽

Craniofacial Anomalies

Download Full-text

Effects of Limited Parental English Proficiency and Identifying As Hispanic on Psychosocial Functioning During Covid-19 in Children with Craniofacial Anomalies

Journal of the American College of Surgeons ◽

10.1016/j.jamcollsurg.2021.08.431 ◽

2021 ◽

Vol 233 (5) ◽

pp. e160

Author(s):

Michelle K. Oberoi ◽

Kelly X. Huang ◽

Vivian J. Hu ◽

Rachel M. Caprini ◽

Sri Harshini Malapati ◽

...

Keyword(s):

Psychosocial Functioning ◽

English Proficiency ◽

Craniofacial Anomalies

Download Full-text

Mediators and theories of change in psychotherapy for young people with personality disorders: a systematic review protocol

10.31219/osf.io/ctxw8 ◽

2021 ◽

Author(s):

Jana Volkert ◽

Svenja Taubner ◽

Rasa Barkauskiene ◽

Jose M. Mestre ◽

Celia M.D. Sales ◽

...

Keyword(s):

Systematic Review ◽

Young People ◽

Personality Disorders ◽

Psychosocial Functioning ◽

Psychological Treatment ◽

Open Science ◽

Data Set ◽

Psychological Treatments ◽

Theories Of Change ◽

Prospective Longitudinal

Background: Personality disorders (PDs) are a severe health issue already prevalent among adolescents and young adults. Early detection and intervention offer the opportunity to reduce disease burden and chronicity of symptoms and to enhance long-term functional outcomes. While psychological treatments for personality disorders have been shown to be effective for young people, the mediators and specific change mechanisms of treatment are still unclear. Aim: As part of the “European Network of Individualized Psychotherapy Treatment of Young People with Mental Disorders” (TREATme), funded by the European Cooperation in Science and Technology (COST), we will conduct a systematic review to summarize the existing knowledge on mediators of treatment outcome and theories of change in psychotherapy for young people with personality disorders. In particular, we will evaluate whether mediators appear to be common or specific to particular age groups, treatment models, or outcome domains (e.g., psychosocial functioning, life quality, adverse treatment effects). Method: We will follow the reporting guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. Electronic databases (PubMed, PsycINFO) have been systematically searched for prospective, longitudinal, and case–control designs of psychological treatment studies which examine mediators published in English. Participants will be young people between 10 and 30 years of age who suffer from subclinical personality symptoms or have a personality disorder diagnosis and receive an intervention that aims at preventing, ameliorating and/or treating psychological problems. Results: The results will be published in a peer-reviewed journal and at conference presentations and will be shared with relevant stakeholder groups. The data set will be made available to other research groups following recommendations of the open science initiative. Databases with the systematic search will be made openly available following open science initiatives. The review has been registered in PROSPERO (evaluation is pending, registration number ID 248959).Implications: This review will deliver a comprehensive overview on the empirical basis to contribute to the further development of psychological treatments for young people with personality disorders.

Download Full-text