[PP.28.12] 24-HOUR PATTERNS OF CENTRAL AORTIC AND BRACHIAL SYSTOLIC BLOOD PRESSURE IN THE VERY ELDERLY

2016 ◽  
Vol 34 ◽  
pp. e297-e298
Author(s):  
N. EZHOVA ◽  
A. Alam ◽  
Y. Kotovskaya ◽  
Z. Kobalava
2005 ◽  
Vol 98 (6) ◽  
pp. 2287-2291 ◽  
Author(s):  
Allison E. DeVan ◽  
Maria M. Anton ◽  
Jill N. Cook ◽  
Daria B. Neidre ◽  
Miriam Y. Cortez-Cooper ◽  
...  

Decreased central arterial compliance is an emerging risk factor for cardiovascular disease. Resistance training is associated with reductions in the elastic properties of central arteries. Currently, it is not known whether this reduction is from one bout of resistance exercise or from an adaptation to multiple bouts of resistance training. Sixteen healthy sedentary or recreationally active adults (11 men and 5 women, age 27 ± 1 yr) were studied under parallel experimental conditions on 2 separate days. The order of experiments was randomized between resistance exercise (9 resistance exercises at 75% of 1 repetition maximum) and sham control (seated rest in the exercise room). Baseline hemodynamic values were not different between the two experimental conditions. Carotid arterial compliance (via simultaneous B-mode ultrasound and applanation tonometry) decreased and β-stiffness index increased ( P < 0.01) immediately and 30 min after resistance exercise. Immediately after resistance exercise, carotid systolic blood pressure increased ( P < 0.01), although no changes were observed in brachial systolic blood pressure at any time points. These measures returned to baseline values within 60 min after the completion of resistance exercise. No significant changes in these variables were observed during the sham control condition. These results indicate that one bout of resistance exercise acutely decreases central arterial compliance, but this effect is sustained for <60 min after the completion of resistance exercise.


2015 ◽  
Vol 29 (11) ◽  
pp. 1283-1291 ◽  
Author(s):  
Yuan-Ta Shih ◽  
Hao-Min Cheng ◽  
Shih-Hsien Sung ◽  
Shao-Yuan Chuang ◽  
Wei-Chih Hu ◽  
...  

2016 ◽  
Vol 16 (C) ◽  
pp. 96
Author(s):  
lyndsey E. Dubose ◽  
David J. Moser ◽  
Taylor Stecklein ◽  
Emily Harlynn ◽  
William G. Haynes ◽  
...  

Author(s):  
Antonios A. Argyris ◽  
Dimitrios Mouziouras ◽  
Stamatia Samara ◽  
Yi Zhang ◽  
Marios K. Georgakis ◽  
...  

Background: Evidence suggests marginal superiority of static aortic systolic blood pressure (aSBP) compared with brachial SBP regarding the association with organ damage and prognosis of cardiovascular disease. The noninvasive 24-hour aSBP assessment is feasible and associates better with presence of left ventricular hypertrophy compared with 24-hour brachial systolic blood pressure. We aimed at comparing the association of 24-hour aSBP and 24-hour brachial systolic blood pressure with indices of arterial damage and examining the role of 24-hour SBP amplification variability (within-subjects’ SD) in this association. Methods: Consecutive subjects referred for cardiovascular disease risk assessment underwent 24-hour aortic and brachial ambulatory BP monitoring using a validated oscillometric device (Mobil-O-Graph). Arterial damage was assessed by carotid intima-media thickness and detection of carotid and femoral atheromatosis (plaque presence). Results: Cross-sectionally 501 individuals (aged 54±13 years, 57% men, 80% hypertensives) were examined. Multivariable analysis revealed superiority of 24-hour aSBP regarding the association with intimal-medial thickness, carotid hypertrophy and carotid—but not femoral—atheromatosis. In receiver operator characteristics analysis, 24-hour aBP displayed a higher discriminatory ability—compared to 24-hour brachial systolic blood pressure—for the detection of both carotid hypertrophy (area under the curve, 0.662 versus 0.624, P <0.05) and carotid atheromatosis (area under the curve, 0.573 versus 0.547, P <0.05). This effect was more prominent in individuals with above-median 24-hour SD of SBP amplification. Conclusions: Our results suggest that 24-hour aSBP assessment may be of significant value in clinical practice to detect site-specific arterial damage on the basis of pressure amplification variability and should be prospectively examined in clinical trials.


2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
D Terentes-Printzios ◽  
K Aznaouridis ◽  
N Ioakeimidis ◽  
V Gardikioti ◽  
P Xaplanteris ◽  
...  

Abstract Background/Introduction Hypertension is associated with higher cardiovascular risk as well as several markers of subclinical target organ damage (TOD). Albumin to creatinine ratio (ACR) in urine has been recognized as an independent risk factor for cardiovascular events. Purpose We hypothesized that there is a relationship between ACR and markers of TOD in never-treated hypertensives. Methods We enrolled 924 consecutive essential hypertensives (mean age 53±12 years, 486 males) without known cardiovascular disease (CVD). Markers of subclinical TOD [left ventricular mass index (LVMI), pulse wave velocity (PWV), ankle-brachial index (ABI) and estimated glomerular filtration rate (eGFR)] were evaluated in all patients. LVMI was assessed echocardiographically using the Devereux formula. Carotid-femoral PWV was estimated with the Complior device. eGFR was calculated by the Cockcroft-Gault formula. ABI was calculated by dividing the highest ankle systolic blood pressure by the highest brachial systolic blood pressure. Results ACR exhibited significant association with LVMI (r=0.277, p&lt;0.001, Figure), PWV (r=0.277, p&lt;0.001) ABI (r=−0.078, p=0.018) and eGFR (r=−0.100, p=0.002). In further analysis, ACR was associated with TOD as suggested by the 2018 European Guidelines for Hypertension [left ventricular hypertrophy (LVMI&gt;115 g/m2 in men and &gt;95 g/m2 in women), increased PWV (PWV&gt;10m/s), decreased ABI (ABI&lt;0.9) and decreased renal function (eGFR&lt;60ml/min)]. Specifically, ACR exhibited significant association with the number of TOD and this association was independent of age and gender (p&lt;0.05). Conclusions Our findings support the close relationship between ACR and TOD in hypertension, as well as, the predictive ability of ACR for TOD. FUNDunding Acknowledgement Type of funding sources: None. Association between LVMI and ACR


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