A Rotavirus Vaccine for Prophylaxis of Infants Against Rotavirus Gastroenteritis

2004 ◽  
Vol 23 (Supplement) ◽  
pp. S179-S182 ◽  
Author(s):  
Beatrice De Vos ◽  
Timo Vesikari ◽  
Alexandre C. Linhares ◽  
Bel??n Salinas ◽  
Irene P??rez-Schael ◽  
...  
Children ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 263
Author(s):  
Dong Hyun Kim ◽  
Dong Jun Ha ◽  
Yeong Seok Lee ◽  
Min Jun Chun ◽  
Young Se Kwon

There have been no large-scale studies on the epidemiology of benign convulsions with mild gastroenteritis (CwG) since the introduction of the rotavirus vaccine in South Korea in 2007. This study aimed to analyze the trends in rotavirus gastroenteritis (RVGE) and rotavirus-associated CwG (RaCwG) after rotavirus vaccination. Further, we aimed to analyze changes in norovirus gastroenteritis (NVGE) and norovirus-associated CwG (NaCwG) using nationwide data from the Korean Health Insurance Review and Assessment Service. Between 2007 and 2019, this study analyzed children aged <6 years who were diagnosed with RVGE, NVGE, RaCwG and NaCwG. The changes in the prevalence of each disease and the ratio of CwG to enteritis were analyzed and the effects of age, sex and season were also analyzed. RVGE, RaCwG, NVGE and NaCwG were diagnosed in 273,898, 4246, 35,593 and 337 patients, respectively. The prevalence of RVGE was on a decreasing trend every year, but the prevalence of NaCwG and NVGE was on an increasing trend. There was a significant annual increase in the ratio of CwG to enteritis in both viruses. In order to control the prevalence of RaCwG, measures other than the rotavirus vaccine are required and measures to prevent norovirus are necessary.


2018 ◽  
Vol 90 (6) ◽  
pp. 1040-1046 ◽  
Author(s):  
Nusrat Khandoker ◽  
Aksara Thongprachum ◽  
Sayaka Takanashi ◽  
Shoko Okitsu ◽  
Shuichi Nishimura ◽  
...  

Author(s):  
Francesco Napolitano ◽  
Abdoulkader Ali Adou ◽  
Alessandra Vastola ◽  
Italo Francesco Angelillo

This study was designed to investigate the knowledge, beliefs, and behaviors about rotavirus infection and its vaccination in a sample of parents in Naples, Italy. The survey was conducted between June and December 2018 among parents of children aged 3 months to 3 years. A total of 40.7% of the study subjects declared that they had heard about rotavirus infection and 60.8% and 59.2% were aware about the vaccination and of its availability in Italy. Parents with a child aged <1 year and those who reported the physicians as source of information were more likely to have heard about rotavirus infection and to know that the vaccination is available in Italy. More than half (56.4%) were worried that their children could have a rotavirus gastroenteritis and this was most likely to occur in those who have heard about rotavirus infection. Only 15.3% declared that they had immunized their children against rotavirus infection. Parents who considered it dangerous for their children to contract the rotavirus gastroenteritis, those who considered the rotavirus vaccine useful, and those who had received information by physicians were more likely to have vaccinated their children against the infection. More than half of the parents who did not immunize their children expressed their willingness to vaccinate them. Developing and implementing additional public education programs are needed for better knowledge toward rotavirus infection and vaccination and a high coverage among parents.


Vaccine ◽  
2010 ◽  
Vol 28 (47) ◽  
pp. 7501-7506 ◽  
Author(s):  
Sachin N. Desai ◽  
Daina B. Esposito ◽  
Eugene D. Shapiro ◽  
Penelope H. Dennehy ◽  
Marietta Vázquez

2016 ◽  
Vol 63 (5) ◽  
pp. 634-641 ◽  
Author(s):  
E. Ross Colgate ◽  
Rashidul Haque ◽  
Dorothy M. Dickson ◽  
Marya P. Carmolli ◽  
Josyf C. Mychaleckyj ◽  
...  

2009 ◽  
Vol 16 (3) ◽  
pp. 382-386 ◽  
Author(s):  
H Fred Clark ◽  
Diane Lawley ◽  
Laura A. Mallette ◽  
Mark J. DiNubile ◽  
Richard L. Hodinka

ABSTRACT A pentavalent rotavirus vaccine for infants became available in the United States in February 2006. By 2007, vaccination rates nationwide were estimated to be ∼50%. We studied the effectiveness of the vaccine in a real-world setting outside of a clinical trial. All children presenting to The Children's Hospital of Philadelphia with acute gastroenteritis have been monitored for the presence of rotavirus antigen in the stool by enzyme-linked immunosorbent assay (ELISA [followed by genotyping if ELISA positive]) since the 1994-1995 epidemic season, presenting a unique opportunity to assess the impact of the recently introduced vaccine. The annual number of community-acquired cases over the preceding 13 years had approached or exceeded 100, with 271 cases in 2005 to 2006 and 167 cases in 2006 to 2007. In the 2007-2008 season, only 36 community-acquired cases were identified, representing an 87% reduction from the same period in 2005 to 2006. G3 was the predominant serotype, accounting for 15 community cases (42%). Our study is limited by its observational design using historical comparisons. Nonetheless, the abrupt decline in rotavirus gastroenteritis cases during the 2007-2008 season likely resulted from vaccination. Because protection rates appeared to have exceeded vaccination rates, herd immunity may have contributed to some degree to the effectiveness of the vaccine.


2020 ◽  
Author(s):  
Amir Klivitsky ◽  
Salam Algabria ◽  
Gideon Paret ◽  
Nadav Michaan ◽  
Lior Goldberg ◽  
...  

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