INHIBITION OF PANCREATIC ADENOCARCINOMA CELL PROLIFERATION AND INVASION BY RNAI-MEDIATED KNOCKDOWN OF THE PRL-2 TYROSINE PHOSPHATASE

Pancreas ◽  
2007 ◽  
Vol 35 (4) ◽  
pp. 397-398
Author(s):  
P. L. Crowell ◽  
A. M. Wilson ◽  
S. R. Werner ◽  
R. M. Thomas
2018 ◽  
Vol 54 (60) ◽  
pp. 8359-8362 ◽  
Author(s):  
Qian Zhao ◽  
Cheng Peng ◽  
Hua Huang ◽  
Shuai-Jiang Liu ◽  
Ya-Jun Zhong ◽  
...  

We report the synthesis of a library of chiral THIQ-fused spirooxindoles. The most potent compound inhibits Ras-GTP, ultimately leading to mitochondrial apoptosis.


Oncotarget ◽  
2018 ◽  
Vol 9 (15) ◽  
pp. 11977-11988 ◽  
Author(s):  
Xuelian Xiao ◽  
Daheng Yang ◽  
Xue Gong ◽  
Dongping Mo ◽  
Shiyang Pan ◽  
...  

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