Perinatal Outcomes Associated With Obstructive Sleep Apnea in Obese Pregnant Women

2013 ◽  
Vol 121 (4) ◽  
pp. 875-876
Author(s):  
Adeola G. Atilade ◽  
Keri Holloway ◽  
Cassandra E. Henderson
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Pregnant Women ◽  
Perinatal Outcomes ◽  
Obstructive Sleep

scholarly journals Obstructive Sleep Apnea Is Associated With Altered Glycemic Patterns in Pregnant Women With Obesity

2019 ◽  
Vol 104 (7) ◽  
pp. 2569-2579 ◽  
Author(s):  
Sarah S Farabi ◽  
Linda A Barbour ◽  
Kristy Heiss ◽  
Nicole M Hirsch ◽  
Emily Dunn ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Pregnant Women ◽  
Area Under The Curve ◽  
Perinatal Outcomes ◽  
Late Pregnancy ◽  
Apnea Hypopnea Index ◽  
Oral Glucose ◽  
Continuous Glucose Monitor ◽  
Obstructive Sleep

AbstractObjectiveOften unrecognized, obstructive sleep apnea (OSA) worsens over pregnancy and is associated with poorer perinatal outcomes. The association between OSA in late pregnancy and metabolic biomarkers remains poorly understood. We tested the hypothesis that OSA in pregnant women with obesity is positively correlated with 24-hour patterns of glycemia and IR despite controlling for diet.DesignPregnant women (32 to 34 weeks’ gestation; body mass index, 30 to 40 kg/m2) wore a continuous glucose monitor for 3 days. OSA was measured in-home by WatchPAT 200™ [apnea hypopnea index (AHI), oxygen desaturation index (ODI; number per hour)]. Fasting blood was collected followed by a 2-hour, 75-g, oral glucose tolerance test to measure IR. Association between AHI and 24-hour glucose area under the curve (AUC) was the powered outcome.ResultsOf 18 women (29.4 ± 1.4 years of age [mean ± SEM]), 12 (67%) had an AHI ≥5 (mild OSA). AHI and ODI were correlated with 24-hour glucose AUC (r = 0.50 to 0.54; P ≤ 0.03) and mean 24-hour glucose (r = 0.55 to 0.59; P ≤ 0.02). AHI and ODI were correlated with estimated hepatic IR (r = 0.59 to 0.74; P < 0.01), fasting free fatty acids (fFFAs; r = 0.53 to 0.56; P < 0.05), and waking cortisol (r = 0.49 to 0.64; P < 0.05).ConclusionsMild OSA is common in pregnant women with obesity and correlated with increased glycemic profiles, fFFAs, and estimates of hepatic IR. OSA is a potentially treatable target to optimize maternal glycemia and metabolism, fetal fuel supply, and pregnancy outcomes.

scholarly journals Perinatal Outcomes Associated With Obstructive Sleep Apnea in Obese Pregnant Women

2012 ◽  
Vol 120 (5) ◽  
pp. 1085-1092 ◽  
Author(s):  
Judette Louis ◽  
Dennis Auckley ◽  
Branko Miladinovic ◽  
Anna Shepherd ◽  
Patricia Mencin ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Pregnant Women ◽  
Perinatal Outcomes ◽  
Obstructive Sleep

Obstructive sleep apnea screening and perinatal outcomes in Korean pregnant women

2012 ◽  
Vol 287 (3) ◽  
pp. 429-433 ◽  
Author(s):  
Hyun Sun Ko ◽  
Moon Young Kim ◽  
Yeun Hee Kim ◽  
Jihyun Lee ◽  
Yong-Gyu Park ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Pregnant Women ◽  
Perinatal Outcomes ◽  
Obstructive Sleep

1337-P: Metabolomic Profile Associated with Obstructive Sleep Apnea Severity in Obese Pregnant Women with Gestational Diabetes

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1337-P
Author(s):  
SIRIMON REUTRAKUL ◽  
NARICHA CHIRAKALWASAN ◽  
SURANUT CHAROENSRI ◽  
SOMVANG AMNAKKITTIKUL ◽  
SUNEE SAETUNG ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Gestational Diabetes ◽  
Pregnant Women ◽  
Metabolomic Profile ◽  
Obstructive Sleep Apnea Severity ◽  
Obstructive Sleep

EFFECT OF OBSTRUCTIVE SLEEP APNEA ON INCIDENCE OF PREECLAMPSY IN PREGNANT WOMEN: A SYSTEMATIC REVIEW

2020 ◽  
Author(s):  
Sulis Diana ◽  
◽  
Chatarina Umbul Wahyuni ◽  
Budi Prasetyo ◽  
◽  
...  
Keyword(s):  
Systematic Review ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Pregnant Women ◽  
Obstructive Sleep

Management of Obstructive Sleep Apnea in Pregnant Women

2012 ◽  
Vol 119 (4) ◽  
pp. 864-868 ◽  
Author(s):  
Judette Louis ◽  
Dennis Auckley ◽  
Norman Bolden
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Pregnant Women ◽  
Obstructive Sleep
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