Unusual Occurrence of a Melanoma with Intermixed Epithelial Component: A True Melanocarcinoma?: Case Report and Review of Epithelial Differentiation in Melanoma by Light Microscopy and Immunohistochemistry

2007 ◽  
Vol 29 (4) ◽  
pp. 395-399 ◽  
Author(s):  
Y Hannah Wen ◽  
Shah Giashuddin ◽  
Richard L Shapiro ◽  
Elsa Velazquez ◽  
Jonathan Melamed
1992 ◽  
Vol 78 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Simonetta Bianchi ◽  
Giorgio Malatantis ◽  
Gaetano Cardona ◽  
Giancarlo Zampi

A case of primary osteogenic sarcoma of the breast is reported. It should be distinguished from carcinoma with extensive osseous metaplasia. The results of light and electron microscopy including an immunohistochemical study are presented. Immunohistochemical and ultrastructural studies proved that the lesion, in the absence of epithelial differentiation, was a primary osteogenic sarcoma of the breast rather than a carcinoma with extensive osseous metaplasia. Diagnosis may be delayed because the tumor is confused clinically and mammographically with a calcific fibroadenoma.


2021 ◽  
Vol 12 (2) ◽  
pp. 180-182
Author(s):  
Issam Msakni ◽  
Aya Khemir ◽  
Nada Mansouri

Carcinosarcoma is a rare biphasic tumor made of two malignant components—the epithelial component and the stromal component—that can develop anywhere on the body, but mainly in sun-exposed areas. We report the case of a 78-year-old male who presented himself with a right temporal tumor in the ear 10 cm in diameter. A biopsy suggested a sarcoma. The patient underwent an extensive surgical resection of the temporal mass and the ipsilateral ear. A microscopic examination of the tumor revealed two intermixed malignant contingents. The epithelial component was made of atypical basaloid cells arranged in nests with peripheral palisading and expressing cytokeratin. The stromal component was made of atypical spindle cells expressing smooth muscle actin (SMA). A diagnosis of primary cutaneous carcinosarcoma with clear margins was reached. The patient is alive and without recurrence after twelve months of a follow-up period.


2019 ◽  
Vol 9 ◽  
pp. 10
Author(s):  
Neetu Soni ◽  
Nour T Aly ◽  
Aditi Vidholia ◽  
Fabiana Policeni

Phyllodes tumors (PTs) are a rare fibroepithelial tumor of the breast. Histopathological confirmation of stromal and epithelial component is required for making the diagnosis of PT, and stromal component carries an increased risk of sarcomatous transformation. We present imaging findings of a histologically proven case of malignant PT with heterologous liposarcomatous transformation of the breast.


2014 ◽  
Vol 2 (1) ◽  
pp. 106
Author(s):  
J R K Lande ◽  
K Chandra Sekhar ◽  
B A Rama Krishna ◽  
Hari Hara Sastry ◽  
S Vijaya Mohan ◽  
...  

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