Appendectomy is Oncologically Equivalent to Right Hemicolectomy for Well Differentiated T1 Appendiceal Adenocarcinoma

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Samer S. AlMasri ◽  
Abdulrahman Y. Hammad ◽  
Aatur D. Singhi ◽  
Alessandro Paniccia ◽  
Amer H. Zureikat ◽  
...  
Keyword(s):  
Right Hemicolectomy ◽  
Appendiceal Adenocarcinoma ◽  
Well Differentiated

scholarly journals Surgical Procedures for Neuroendocrine Neoplasms of the Appendix: A Consensus Guideline Review

2017 ◽  
Vol 10 (2) ◽  
pp. 87-89
Author(s):  
Paulina Tr. Vladova ◽  
Sergey D. Iliev ◽  
Savelina L. Popovska
Keyword(s):  
Surgical Procedures ◽  
Surgical Approach ◽  
Survival Rates ◽  
Right Hemicolectomy ◽  
Neuroendocrine Neoplasms ◽  
Consensus Guideline ◽  
Surgical Interventions ◽  
Proliferation Activity ◽  
The Difference ◽  
Well Differentiated

Summary According to the consensus and the recommendations of the European Neuroendocrine Tumor Society (ENETS), the frequency of appendicular neuroendocrine tumors (NETs) is 0.15-0.6/100 000 a year. They are found a little more often in women aged between 40 and 50. Neuroendocrine neoplasms of the appendix are about 30 to 80% of all appendicular tumors. Their evolution is usually asymptomatic. They are diagnosed accidentally during a conventional or laparoscopic appendectomy. In the past, the surgical approach used to depend on the localization of the tumor. Currently, its localization is not a significant factor in the choice of a surgical approach. Our purpose wass to present the consensus guideline and the recommendations of ENETS 2017 for surgical procedures in neuroendocrine neoplasms of the appendix and analyze the difference in the survival rate in different surgical interventions. The literature overview includes studies on surgical treatment of neuroendocrine neoplasms of the appendix and takes into consideration the last consensus guideline of ENETS 2017 on the topic. ENETS recommends a simple appendectomy in well- differentiated appendix tumors smaller than 2 cm, regardless of their localization. Right hemicolectomy is performed for in tumors sized between 1 cm and 2 cm with positive resection lines, with deep mesoappendiceal invasion, high proliferation activity (G2) and vascular invasion. For tumors over larger than 2 cm – right hemicolectomy is recommended. Although current studies have pointed out no significant differences in survival rates between appendectomy for neuroendocrine neoplasms of the appendix and right hemicolectomy, ENETS 2017 suggests that the latest consensus guidelines should be followed.

scholarly journals Carcinoma Colon in a Patient with Eosinophilic Gastroenteritis

2018 ◽  
Vol 09 (04) ◽  
pp. 196-200
Author(s):  
Rachit Agarwal ◽  
Piyush Ranjan ◽  
Sunita Bhalla
Keyword(s):  
Right Hemicolectomy ◽  
Eosinophilic Gastroenteritis ◽  
Fecal Fistula ◽  
Emergency Laparotomy ◽  
Anastomotic Site ◽  
Surgical Specimen ◽  
Eosinophilic Colitis ◽  
Uncommon Disease ◽  
Well Differentiated ◽  
Carcinoma Colon

AbstractEosinophilic gastroenteritis is an uncommon disease which can involve all layers of the gastrointestinal tract anywhere from the esophagus to colon. Clinical features depend upon the site of involvement and layer of GI tract involved. It is an inflammatory disease with remitting and relapsing course. We report a case which presented with discharging fecal fistula in lower abdomen after emergency laparotomy. Initial colonoscopy showed stricture with nodularity of the IC junction and biopsy showed features of eosinophilic gastroenteritis. Due to persistence of fistula he underwent right hemicolectomy with illeo-transverse anastomosis. Biopsy from surgical specimen showed well differentiated adenocarcinoma and eosinophilic infiltrate in muscularis. Surveillance colonoscopy done six months later showed ulcer at anastomotic site and biopsy showed features of eosinophilic colitis. The clinical course of this patient circumstantially indicates a linkage of eosinophilic colitis with carcinoma colon. This is the first reported case of association of eosinophilic colitis with carcinoma colon. We discuss in detail the clinical and pathological features of eosinophilic enteritis and possible mechanisms linking eosinophilc enteritis with carcinoma.

Appendiceal Neoplasm

2020 ◽  
Author(s):  
Tushar Samdani ◽  
Garrett M. Nash
Keyword(s):  
Incidental Finding ◽  
Right Hemicolectomy ◽  
World Health ◽  
Low Grade ◽  
Depth Of Invasion ◽  
Appendiceal Neoplasm ◽  
Appendiceal Adenocarcinoma ◽  
Appendiceal Neoplasms ◽  
Cancer Guidelines ◽  
Health Organization

Appendiceal neoplasms are rare and are typically found in the setting of metastatic disease or, less commonly, as an incidental finding in an appendectomy specimen in cases of appendicitis or an unrelated condition. The World Health Organization classifies appendiceal neoplasms as benign or malignant. The management of the mucinous variety of appendiceal neoplasms is influenced by the presence of peritoneal involvement. Selected patients with metastatic appendiceal neoplasms are treated with surgical cytoreduction and intraperitoneal chemotherapy and/or systemic chemotherapy. Nonmetastatic appendiceal adenocarcinoma is typically managed with staging right colectomy and adjuvant fluorouracil-based chemotherapy based on colon cancer guidelines. Neuroendocrine tumors (NETs) constitute 50 to 77% of all appendiceal neoplasms and 19% of all gastrointestinal NETs. Right hemicolectomy is indicated if the size of the NET is more than 2 cm, the base of the appendix is involved, it is a high-grade tumor, or the depth of invasion of the mesoappendix is more than 3 mm. This review contains 7 figures, 9 tables and 36 references Key Words: appendiceal adenocarcinoma, appendiceal adenoma, appendiceal neoplasm, diffuse peritoneal adenomucinosis, Goblet cell carcinoid of appendix, low-grade appendiceal mucinous neoplasm, mucocele of appendix, neuroendocrine tumor of appendix, peritoneal mucinous carcinomatosis (PMCA), pseudomyxoma peritonei  

Appendiceal Mucocele of Mucinous Cystadenocarcinoma with a Cutaneous Fistula

2002 ◽  
Vol 30 (4) ◽  
pp. 452-456 ◽  
Author(s):  
A Nakao ◽  
S Sato ◽  
A Nakashima ◽  
A Nabeyama ◽  
N Tanaka
Keyword(s):  
Iliac Fossa ◽  
Right Hemicolectomy ◽  
Cystic Mass ◽  
Japanese Woman ◽  
Mucinous Cystadenocarcinoma ◽  
Appendiceal Mucocele ◽  
Old Japanese ◽  
Well Differentiated ◽  
The Right ◽  
Skin Fistula

We report a novel case of cystadenocarcinoma forming an appendiceal mucocele with development of a skin fistula. The patient was a 75-year-old Japanese woman who originally presented with a skin ulcer on the right flank (inferior to the ribs and superior to the iliac bone) with mucus discharge. The serum concentration of carcinoembryonal antigen was elevated (57.4 ng/ml). Ultrasonography and computed tomography demonstrated a cystic mass with septations in the right iliac fossa. Fistulography from the skin ulceration showed a communication via the fistula to the caecum. A right hemicolectomy and enbloc resection of the skin fistula was performed. The histological findings revealed a well-differentiated mucinous cystadenocarcinoma of the appendix. The patient has been alive for 7 years following surgery without any sign of recurrence. This report is of interest as it demonstrates that tumour rupture to the extraperitoneal space could result in a good outcome by preventing the development of pseudomyxoma peritonei.

scholarly journals Tumor Neuroendocrino del Ciego: Reporte de Caso

2019 ◽  
Vol 30 (2) ◽  
Author(s):  
Paúl Andrade
Keyword(s):  
Intestinal Obstruction ◽  
Neuroendocrine Tumor ◽  
Male Patient ◽  
Neuroendocrine Carcinoma ◽  
Histopathological Examination ◽  
Primary Anastomosis ◽  
Right Hemicolectomy ◽  
Small Cells ◽  
Aggressive Tumor ◽  
Well Differentiated

Neuroendocrine carcinoma (NEC) of the colon is a rare and very aggressive tumor, generally diagnosticated in an incidental way and during resolution of complications such as perforation or intestinal obstruction. The case of a 58-year-old male patient who was surgically intervened for presenting localized peritonitis pedhora scan to a perforated blind neuroendocrine tumor. Right hemicolectomy whit ganglion D2 resection and ileo – transverse primary anastomosis was performed. Histopathological examination described a well-differentiated neuroendocrine carcinoma of small cells, with no vascular or neuronal infiltration. Now the patient is awaiting chemotherapy without the need for secondary surgical review.

scholarly journals COEXISTENCE OF TUBERCULOSIS AND ADENOCARCINOMA OF THE COLON

2003 ◽  
Vol 42 (145) ◽  
pp. 39-41
Author(s):  
Yogendra Singh ◽  
G Sayami ◽  
M Khakurel
Keyword(s):  
Histopathological Examination ◽  
Psoas Abscess ◽  
Iliac Fossa ◽  
Right Hemicolectomy ◽  
Ascending Colon ◽  
Colonic Tuberculosis ◽  
Adenocarcinoma Of The Colon ◽  
Well Differentiated ◽  
The Right

ABSTRACTA 60-years-old, male patient presented with a-tender swelling in the right iliac fossa with right hip flexiondeformity suggesting of psoas abscess. Following emergency drainage of faeculant pus, the general conditionof the patient improved. The barium enema showed leaking ascending colonic ulcer and colonoscopicexamination revealed nonspecific ulcerative lesion in the ascending colon. Repeat investigations were alsonon-conclusive except there was a stricture at the ascending colon on colonoscopy. A second operationshowed that there was a huge mass of terminal ileum, cecum and ascending colon and perforation of ascendingcolonic ulcer most likely carcinoma. Right hemicolectomy was performed with uneventful postoperativeperiod. Histopathological examination revealed well differentiated adenocarcinoma limited to the musclelayer of the ascending colon and features suggestive of colonic tuberculosis at the same site. Antituberculartreatment was completed with regular follow-up and monitoring on CEA level. Patient has been doing well3 years postoperatively. Although rare, the coexistence of colonic tuberculosis with carcinoma may occur. Adefinitive diagnosis can be established only by histological examination.Key Words: Colonic tuberculosis, Adenocarcinoma, Histology.

scholarly journals Colon cancer in malrotated gut: A case report

2021 ◽  
pp. 386-387
Author(s):  
Arnab Gupta ◽  
Subrata Kumar Sahu ◽  
Samir Bhattacharya ◽  
Sudip Haldar
Keyword(s):  
Colon Cancer ◽  
Histopathological Examination ◽  
Incidental Finding ◽  
Vascular Anomaly ◽  
Right Hemicolectomy ◽  
Hepatic Flexure ◽  
Colon Cancers ◽  
Mesenteric Vessels ◽  
Well Differentiated

Malrotation of the gut is a rare congenital anomaly that mostly presents in the 1st month of life. Very rarely, it is found during adulthood either as an asymptomatic incidental finding or at autopsy. Presenting in adulthood with colon cancers is extremely rare. Here, we present the case of a middle-aged male patient with unexplained anemia which on investigation was found to have adenocarcinoma at the hepatic flexure of the colon. The staging computed tomography scan of the abdomen showed the growth at the hepatic flexure with malrotation of the gut. During the laparoscopic assessment, the cecum and ascending colon were found on the left side, and hence, a formal midline incision was made. Cecum was found on the left of the midline along with Ladd’s band. Extended right hemicolectomy was performed, dividing the Ladd’s band, taking care of the anomalous position of superior mesenteric vessels. The post-operative period was uneventful. Histopathological examination revealed this to be well-differentiated adenocarcinoma (pT3N1b). He thereafter received adjuvant chemotherapy and remains well after 5 years of follow-up. Presentation of malrotation of the gut in adulthood is seen in only 10–15% of cases as an incidental finding or at autopsy. Cancers in the colon in these patients are extremely rare. The treatment for colon cancer remains the same although one has to be careful about the vascular anomaly during the resection.

Cytology of Pseudomyxoma Peritonei Associated with Well-Differentiated Appendiceal Adenocarcinoma

2008 ◽  
Vol 52 (3) ◽  
pp. 391-394
Author(s):  
Neelaiah Siddaraju ◽  
Jayanthi Soundararaghavan ◽  
Krishnan R. Iyengar
Keyword(s):  
Pseudomyxoma Peritonei ◽  
Appendiceal Adenocarcinoma ◽  
Well Differentiated

scholarly journals Primary Appendiceal Adenocarcinoma Presenting with Hematochezia due to the Invading Tumor in the Sigmoid Colon

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Tatsuya Suzuki ◽  
Yasuhiro Yamamoto ◽  
Toshihiko Torigoe ◽  
Shoichiro Mizukami ◽  
Kengo Shigehara
Keyword(s):  
Sigmoid Colon ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
Pathological Examination ◽  
Ileocecal Resection ◽  
Tubular Adenocarcinoma ◽  
En Bloc ◽  
Appendiceal Tumor ◽  
Appendiceal Adenocarcinoma ◽  
Well Differentiated

Primary appendiceal tumors are rare malignancies; some cases have been described to invade other organs, and this represents a very rare clinical condition. We report a case of appendiceal adenocarcinoma invading the sigmoid colon and a review of similar cases. A 69-year-old woman with complaints of hematochezia was admitted to the hospital. Colonoscopy revealed a tumor in the sigmoid colon, which was a well-differentiated tubular adenocarcinoma. A computed tomography scan showed an appendiceal mass that involved the sigmoid colon, suggesting an appendiceal cancer invading the sigmoid colon. Ileocecal resection with extended lymphadenectomy and en bloc resection of the sigmoid colon was performed. The appendiceal tumor involved the sigmoid colon and the terminal ileum. The ileocecal part which included the tumor and the involved sigmoid colon was resected in total. Macroscopic findings showed that the appendiceal tumor made a fistula with the sigmoid colon. Pathological examination revealed that the tumor was a well-differentiated tubular adenocarcinoma that invaded the sigmoid colon. The final pathological stage was T4bN0M0, stage IIC. The patient was discharged from the hospital uneventfully. She was alive without relapse after a 20-month follow-up. Although an appendiceal tumor invading the rectosigmoid region is rare, a preoperative diagnosis can be obtained that facilitates the planning of a suitable surgical procedure: en bloc resection of the ileocecal part and the rectosigmoid part.

scholarly journals RADICAL SURGICAL TREATMENT OF NEUROENDOCRINE TUMORS OF APPENDIX IN CHILDREN – Polish multicenter study

2021 ◽  
Author(s):  
Małgorzata Panek ◽  
Marek Szymczak ◽  
Wojciech Górecki ◽  
Jerzy Niedzielski ◽  
Piotr Kaliciński
Keyword(s):  
Overall Survival ◽  
Survival Rate ◽  
Neuroendocrine Tumors ◽  
Right Hemicolectomy ◽  
Ileocecal Resection ◽  
Overall Survival Rate ◽  
Secondary Surgery ◽  
Extended Surgery ◽  
Well Differentiated

IntroductionThe aim of study was to examine management of pediatric appendiceal neuroendocrine tumors (ANET) in Poland.Material and methodsRecords of 27 patients with ANET diagnosed incidentally after appendectomy in last decade.ResultsWell-differentiated NET G1/G2 was diagnosed in 25 and well-differentiated neuroendocrine carcinoma G3 in 2 patients. Extended surgery was performed primary in one instance and secondary in 10 patients (right hemicolectomy in 9, ileocecal resection in one) without adjuvant chemotherapy. Follow-up ranged 1-121 months. Recurrence after secondary surgery was observed in one patient (3,7%).ConclusionsApplying ENETS guidelines resulted in 100% overall survival rate of patients with NET.

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