A stitch in time saves early spinal anaesthesia-induced hypotension

2021 ◽  
Vol 38 (11) ◽  
pp. 1210
Author(s):  
Nitika Goel ◽  
Kajal Jain
Keyword(s):  
Spinal Anaesthesia ◽  
Induced Hypotension

Ondansetron reduces the incidence of hypotension after spinal anaesthesia in non-caesarean delivery: A systematic review and meta-analysis

2021 ◽  
pp. 175045892096415
Author(s):  
Tito D Tubog ◽  
Richard S Bramble
Keyword(s):  
Systematic Review ◽  
Arterial Pressure ◽  
Spinal Anaesthesia ◽  
Caesarean Delivery ◽  
Meta Analysis ◽  
Systolic Arterial Pressure ◽  
Incidence Rates ◽  
Induced Hypotension ◽  
Quality Of Evidence

The incidence rates of spinal anaesthesia-induced hypotension vary depending on the surgical procedures. This systematic review and meta-analysis evaluates the efficacy of prophylactic ondansetron in reducing the incidence of spinal anaesthesia-induced hypotension in non-caesarean delivery. Thirteen trials consisting of 1166 patients were included for analysis. Compared to placebo, there is a low quality of evidence that ondansetron was effective in reducing the incidence of spinal anaesthesia-induced hypotension (RR 0.62, 95% CI 0.44 to 0.87; p = 0.005) and bradycardia (RR 0.54, 95% CI 0.32 to 0.90; p = 0.02). We also found a moderate quality of evidence that ondansetron lowered the number of rescue ephedrine (RR 0.61, 95% CI 0.43 to 0.87; p = 0.007). Patients treated with ondansetron have higher mean arterial pressure 15 to 20 minutes after spinal anaesthesia induction and higher systolic arterial pressure 5, 10, 15 and 20 minutes after spinal anaesthesia. The evidence suggests that prophylactic administration of ondansetron results in the reduction of the incidence of spinal anaesthesia-induced hypotension, bradycardia and rescue ephedrine in patients undergoing non-caesarean delivery under spinal anaesthesia.

Spinal anaesthesia induced hypotension: comparison between patients with and without chronic hypertension

2007 ◽  
Vol 32 (Suppl. 1) ◽  
pp. 35
Author(s):  
P. Coimbra ◽  
J. Peixoto ◽  
N. Fernandes ◽  
L. Barros ◽  
C. Matias ◽  
...  
Keyword(s):  
Spinal Anaesthesia ◽  
Chronic Hypertension ◽  
Induced Hypotension

scholarly journals Spinal Anaesthesia Induced Hypotension and Related Adverse Effects in Caesarean Section Delivery and Neonatal Outcome: A Comparison of Using Crystalloid Pre-Loading and Co- Loading in Caesarean Patients

2020 ◽  
Vol 5 (1) ◽  
pp. 90
Author(s):  
Taneem Mohammad ◽  
Moinul Hossain Chowdhury ◽  
Shamima Akter ◽  
Mohammad Abdul Karim Miah ◽  
Mohammad Mohsin ◽  
...  
Keyword(s):  
Caesarean Section ◽  
Adverse Effects ◽  
Spinal Anaesthesia ◽  
Apgar Score ◽  
Neonatal Outcome ◽  
Induced Hypotension ◽  
Group I ◽  
Caesarean Section Delivery ◽  
Group Ii ◽  
The Difference

Background: Volume loading by rapid infusion of crystalloid solution before/during induction of spinal anaesthesia may effectively reduce the incidence of anaesthesia induced hypotension.Objective:To compare the efficacy of crystalloid pre-loading and co-loading to preventhypotension and related adverse effects as well aspoor neonatal outcome in caesarean section delivery under spinal anaesthesia.Methods:This single blinded randomized controlled clinical trial was conducted in the Department of Anaesthesia, Analgesia & Intensive Care, Dhaka Medical College Hospital, Dhaka, between January 2013 and December 2014. A total of 90 patients were selected –45patients of group I received co-loading with Ringer’s lactatesolution, while another 45 patients of group II received a pre-loading of the same fluid.Blood pressure and heart rate were recorded. Ephedrine and adrenaline were administered as needed to treat hypotension.APGAR scores of the newborn were recorded at 1st minute and 5th minute after delivery. Adverse effects like nausea, vomiting, light headedness and shivering was observed all through during operation and post-operative phase in all patients, if any, and recorded.Results:The incidence of hypotension was 17 (37.8%) in group I (co-loading) and 27 (60%) in group II (pre-loading), which was significantly higher in group II (p<0.05).Adverse effects – nausea, vomiting, light headedness and shivering was observed more in group II patients; however, the difference was not statistically significant. In neonates, APGAR score at 1 minute was found ≤7 in 18 (40.0%) from group I, while 28 (62.2%) from group II; the difference was statistically significant (p<0.05). No significant difference was observed in APGAR score at 5 minutes, as found ≤7 in 6 (13.3%) and 3 (6.7%) in group I andgroup II respectively.Conclusion:Severity of hypotension, increased ephedrine requirement and poor APGAR score wereevident in patients who received crystalloid pre-loading group(group II), which meanscrystalloid co-loading group(group I) procedurewas more effective in preventing spinal anaesthesia induced hypotension and secured better neonatal outcome.International Journal of Human and Health Sciences Vol. 05 No. 01 January’21 Page: 90-95

scholarly journals Prevention of spinal anaesthesia-induced hypotension in the elderly: i.m. methoxamine or combined hetastarch and crystalloid

1998 ◽  
Vol 80 (2) ◽  
pp. 199-203 ◽  
Author(s):  
D J Buggy ◽  
C K Power ◽  
R Meeke ◽  
S O'Callaghan ◽  
C Moran ◽  
...  
Keyword(s):  
Spinal Anaesthesia ◽  
The Elderly ◽  
Induced Hypotension

Prevention of Spinal Anaesthesia-Induced Hypotension in the Elderly

1998 ◽  
Vol 42 (6) ◽  
pp. 332
Author(s):  
D. J. BUGGY ◽  
C. K. POWER ◽  
R. MEEKE ◽  
S. O??CALLAGHAN ◽  
C. MORAN ◽  
...  
Keyword(s):  
Spinal Anaesthesia ◽  
The Elderly ◽  
Induced Hypotension
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