Role of arterial stiffness in the association between hand grip strength and cardiovascular events

AbstractDecreased muscle strength is not only a risk factor for hip fracture in elderly patients, but plays a role in recovery of physical function. Our aim was to assess the role of grip strength measured early after hip fracture, and classified according to the EWGSOP2 criteria in predicting short- and long-term functional recovery. One hundred ninety-one patients with acute hip fracture consecutively admitted to an orthopaedic hospital have been selected. A multidimensional geriatric assessment evaluating sociodemographic variables, cognitive status, functional status and quality of life prior to fracture, as well as perioperative variables were performed. Follow-ups at 3 and 6 months after surgery were carried out to evaluate functional recovery. Multivariate regression models were used to assess the predictive role of handgrip strength. The mean age of the participants was 80.3 ±6.8 years. Thirty-five percent of our patients with clinically relevant hand grip strength weakness were significantly older, more often female, had a lower BMI, and were of worse physical health. They also had a lower cognitive level, lower Barthel index, and lower EQ5D scores before fracture. Multivariate regression analysis adjusted for age and gender revealed that hand grip weakness was an independent predictor of worse functional outcome at 3 and 6 months after hip fracture for both genders and in all age populations. Our study supports the prognostic role of hand grip strength assessed at hospital admission in patients with hip fracture. Thus, clinicians should be encouraged to include hand grip assessment in their evaluation of hip fracture patients in the acute setting in order to optimize treatment of high-risk individuals.

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Kekuatan genggam tangan, skor Child Pugh, dan massa otot pada pasien dengan sirosis hati

Jurnal Gizi Klinik Indonesia ◽

10.22146/ijcn.34302 ◽

2018 ◽

Vol 14 (3) ◽

pp. 122

Author(s):

Amanda Trixie Hardigaloeh ◽

Rino Alvani Gani ◽

Irsan Hasan ◽

Andri Sanityoso Sulaiman

Keyword(s):

Liver Cirrhosis ◽

Liver Function ◽

Grip Strength ◽

Muscle Mass ◽

Cross Sectional Study ◽

Hand Grip Strength ◽

Cost Of Treatment ◽

Cross Sectional ◽

Hand Grip

Background: Malnutrition is independent factor related to morbidity, mortality and high cost of treatment in liver cirrhosis. Hand grip strength (HGS) is one of the method use for malnutrition detection and prognosis evaluation. The correlation of HGS with liver function (Child Pugh score) and muscle mass is controversial. These important evaluation is not yet avalaible in Indonesia.Objective: Aim of this study is to assess the role of HGS measurement in malnutrition and its correlation with liver function and muscle mass.Method: This is a cross-sectional study in liver cirrhosis patients at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital from February to June 2015. Nutritional status was assessed by HGS. Muscle mass was obtained from bioimpedance. Data were analyzed using Spearman correlation test.Results: There were 115 patients liver cirrhosis at Hepatobiliary Clinic of Cipto Mangunkusumo Hospital, 112 patients who fit the inclusion criteria, consisted of 79 men and 33 women with mean age 54.15±10.55 years, median Child Pugh score 6 (5-13) with median HGS 26 (11-50) kgF, mean muscle mass 44.43±8.12 kg. The median intake of energy 1334.82 (604.75-3023.7) kkal, median protein 45.87 (19-114.5) gram. Prevalence of malnutrition according HGS was 33%. Hand grip strength is not correlated with Child Pugh score (p=0.046; r=-0.19) however it is correlated with muscle mass (p<0.00; r=0.70).Conclusion: There are 33% malnutrition cases based on HGS in out patient liver cirrhosis. There is no correlation between HGS with Child Pugh score however HGS is correlated with muscle mass in liver cirrhosis.

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Association of Hand Grip Strength and Stroke: A 4-Year Prospective Cohort Study in China

SSRN Electronic Journal ◽

10.2139/ssrn.3491893 ◽

2019 ◽

Author(s):

Guihao Liu ◽

Yunlian Xue ◽

Sheng Wang ◽

Qingshan Geng

Keyword(s):

Cohort Study ◽

Grip Strength ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Hand Grip Strength ◽

Hand Grip

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Effect of Soft Liner Female Housings Retaining Mandibular Two Implant-Supported Overdentures on Hand Grip Strength and Patient Satisfaction in Egyptian Males

Egyptian Dental Journal ◽

10.21608/edj.2018.79231 ◽

2018 ◽

Vol 64 (4) ◽

pp. 3673-3682

Author(s):

Elsayed Abdel-Khalek

Keyword(s):

Patient Satisfaction ◽

Grip Strength ◽

Hand Grip Strength ◽

Hand Grip ◽

Soft Liner

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Combination of the G-8 Screening Tool and Hand-Grip Strength to Predict Long-Term Overall Survival in Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy

Cancers ◽

10.3390/cancers13133363 ◽

2021 ◽

Vol 13 (13) ◽

pp. 3363

Author(s):

Kristian Kirkelund Bentsen ◽

Olfred Hansen ◽

Jesper Ryg ◽

Ann-Kristine Weber Giger ◽

Stefan Starup Jeppesen

Keyword(s):

Overall Survival ◽

Grip Strength ◽

Cancer Patients ◽

Stereotactic Body Radiotherapy ◽

Statistical Significance ◽

Multivariable Analysis ◽

Hand Grip Strength ◽

Physical Test ◽

Hand Grip

The Geriatric 8 (G-8) is a known predictor of overall survival (OS) in older cancer patients, but is mainly based on nutritional aspects. This study aimed to assess if the G-8 combined with a hand-grip strength test (HGST) in patients with NSCLC treated with stereotactic body radiotherapy can predict long-term OS better than the G-8 alone. A total of 46 SBRT-treated patients with NSCLC of stage T1-T2N0M0 were included. Patients were divided into three groups: fit (normal G-8 and HGST), vulnerable (abnormal G-8 or HGST), or frail (abnormal G-8 and HGST). Statistically significant differences were found in 4-year OS between the fit, vulnerable, and frail groups (70% vs. 46% vs. 25%, p = 0.04), as well as between the normal and abnormal G-8 groups (69% vs. 39%, p = 0.02). In a multivariable analysis of OS, being vulnerable with a hazard ratio (HR) of 2.03 or frail with an HR of 3.80 indicated poorer OS, but this did not reach statistical significance. This study suggests that there might be a benefit of adding a physical test to the G-8 for more precisely predicting overall survival in SBRT-treated patients with localized NSCLC. However, this should be confirmed in a larger study population.

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Clinical Outcomes After Aggressive Active Early Motion and Modified Kleinert Regimens: Comparison of 2 Consecutive Cohorts

Hand ◽

10.1177/15589447211017222 ◽

2021 ◽

pp. 155894472110172

Author(s):

Kaisa Jokinen ◽

Arja Häkkinen ◽

Toni Luokkala ◽

Teemu Karjalainen

Keyword(s):

Quality Of Life ◽

Range Of Motion ◽

Grip Strength ◽

Clinical Outcomes ◽

Flexor Tendon ◽

Hand Grip Strength ◽

Active Motion ◽

Hand Grip ◽

Active Range Of Motion

Background Modern multistrand repairs can withstand forces present in active flexion exercises, and this may improve the outcomes of flexor tendon repairs. We developed a simple home-based exercise regimen with free wrist and intrinsic minus splint aimed at facilitating the gliding of the flexor tendons and compared the outcomes with the modified Kleinert regimen used previously in the same institution. Methods We searched the hospital database to identify flexor tendon repair performed before and after the new regimen was implemented and invited all patients to participate. The primary outcome was total active range of motion, and secondary outcomes were Disabilities of Arm, Shoulder, and Hand; grip strength; globally perceived function; and the quality of life. Results The active range of motion was comparable between the groups (mean difference = 14; 95% confidence interval [CI], −8 to 36; P = .22). Disabilities of Arm, Shoulder, and Hand; grip strength; global perceived function; and health-related quality of life were also comparable between the groups. There was 1 (5.3%) rupture in the modified Kleinert group and 4 (15.4%) in the early active motion group (relative risk = 0.3; 95% CI, 0.04-2.5; P = .3). Conclusions Increasing active gliding with a free wrist and intrinsic minus splint did not improve the clinical outcomes after flexor tendon injury at a mean of 38-month follow-up.

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