scholarly journals Fluctuation in Blood Pressure and Intraocular Pressure in Normal Tension Glaucoma Using Ambulatory Monitoring

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Boo Hui Tan ◽  
Alexandra Young ◽  
Eleonora Bianchi ◽  
Lyndsay Brown ◽  
Andrew J. Tatham
Keyword(s):  
Blood Pressure ◽  
Intraocular Pressure ◽  
Ambulatory Monitoring ◽  
Normal Tension Glaucoma

scholarly journals Risk Factors in Normal-Tension Glaucoma and High-Tension Glaucoma in relation to Polymorphisms of Endothelin-1 Gene and Endothelin-1 Receptor Type A Gene

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Dominika Wróbel-Dudzińska ◽  
Ewa Kosior-Jarecka ◽  
Urszula Łukasik ◽  
Janusz Kocki ◽  
Agnieszka Witczak ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Intraocular Pressure ◽  
Clinical Condition ◽  
Type A ◽  
Normal Tension Glaucoma ◽  
Receptor Type ◽  
Endothelin 1 ◽  
Arterial Blood ◽  
High Tension

The aimof the research is to analyse the influence of polymorphisms of endothelin-1 gene and endothelin-1 receptor type A gene on the clinical condition of patients with primary open angle glaucoma.Methods. 285 Polish patients took part in the research (160 normal-tension glaucoma and 125 high-tension glaucoma). DNA was isolated by standard methods and genotype distributions of four polymorphisms in genes encoding endothelin-1 (K198N) and endothelin-1 receptor type A polymorphisms (C1222T, C70G, and G231A) were determined. Genotype distributions were compared between NTG and HTG groups. The clinical condition of participants was examined for association with polymorphisms.Results. A similar frequency of occurrence of the polymorphic varieties of the studied genes was observed in patients with NTG and HTG. There is no relation between NTG risk factors and examined polymorphisms. NTG patients with TT genotype of K198N polymorphism presented with the lowest intraocular pressure in comparison to GG + GT genotype (p=0.03). In NTG patients with CC genotype of C1222T polymorphism (p=0.028) and GG of C70G polymorphism (p=0.03) the lowest values of mean blood pressure were observed.Conclusions. The studied polymorphic varieties (K198N, C1222T) do have an influence on intraocular pressure as well as arterial blood pressure in NTG patients.

Twenty-four-hour intraocular pressure and blood pressure levels with bimatoprost versus latanoprost in patients with normal-tension glaucoma

2008 ◽  
Vol 92 (9) ◽  
pp. 1227-1231 ◽  
Author(s):  
L Quaranta ◽  
T Pizzolante ◽  
I Riva ◽  
A-B Haidich ◽  
A G P Konstas ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Intraocular Pressure ◽  
Normal Tension Glaucoma

scholarly journals Treatment of Glaucoma Patients with Flammer Syndrome

2021 ◽  
Vol 10 (18) ◽  
pp. 4227
Author(s):  
Katarzyna Konieczka ◽  
Josef Flammer
Keyword(s):  
Blood Pressure ◽  
Intraocular Pressure ◽  
Targeted Therapy ◽  
Normal Tension Glaucoma ◽  
Flammer Syndrome ◽  
Pressure Drops ◽  
Vascular Dysregulation ◽  
Primary Vascular Dysregulation ◽  
Therapy Studies ◽  
Symptoms And Signs

Flammer syndrome (FS) describes a phenotype characterized by the presence of primary vascular dysregulation along with a number of symptoms and signs. Although most people with FS are healthy, FS favors the occurrence of certain diseases, such as normal tension glaucoma. This is because disturbed autoregulation makes the eye more sensitive to intraocular pressure (IOP) spikes or blood pressure drops. Treatment of FS is generally appropriate when patients either suffer greatly from their symptoms or if we can assume that it has contributed to a disease. In glaucoma, this may be the case if the glaucoma damage progresses despite well-controlled IOP. Both the still sparse scientific studies and our long clinical experience suggest that FS-targeted therapy not only relieves the symptoms of FS but also slows the progression of glaucoma damage in selected cases. This description is intended not only to help affected patients but to also motivate clinicians and researchers to conduct therapy studies to confirm or refute our observations.

Nocturnal Blood Pressure Fall on Ambulatory Monitoring in a Large International Database

Hypertension ◽  
1997 ◽  
Vol 29 (1) ◽  
pp. 30-39 ◽  
Author(s):  
Jan A. Staessen ◽  
Leszek Bieniaszewski ◽  
Eoin O'Brien ◽  
Philippe Gosse ◽  
Hiroshi Hayashi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Ambulatory Monitoring ◽  
International Database ◽  
Nocturnal Blood Pressure ◽  
Blood Pressure Fall ◽  
Pressure Fall

scholarly journals Obesity, Blood Pressure, and Intraocular Pressure: A Cross-Sectional Study in Italian Children

Obesity Facts ◽  
2021 ◽  
pp. 1-9
Author(s):  
Claudia Pileggi ◽  
Rosa Papadopoli ◽  
Caterina De Sarro ◽  
Carmelo Giuseppe Angelo Nobile ◽  
Maria Pavia
Keyword(s):  
Blood Pressure ◽  
Intraocular Pressure ◽  
School Children ◽  
Adult Population ◽  
Paediatric Population ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Drinking Habits ◽  
Physical Examinations ◽  
Italian Children

<b><i>Introduction:</i></b> Several studies in the adult population have shown that obesity is an independent risk factor for elevated intraocular pressure (IOP), whereas data in the paediatric population are sparse and controversial. The purpose of the present study is to investigate the relationship between body mass index (BMI), blood pressure (BP), and IOP in healthy school children. <b><i>Methods:</i></b> The survey was conducted among a random sample of 8-year-old Italian students. Data were collected on their health status and behaviours related to obesity (physical activity, food and drinking habits, etc.). Physical examinations, conducted at school, included measurements of height, weight, BP, and IOP. <b><i>Results:</i></b> Five hundred and seventy-six subjects were recruited (92.8% response rate); 42.4% were overweight or obese, 58.9% consumed inadequate daily servings of fruit and vegetables, and 87.5% were involved in sedentary activities. Elevated BP/hypertension (HTN) affected 3.6% and high IOP was revealed in 12.5% of the children. In the multivariate analysis, elevated BP/HTN was the only significant determinant of ocular HTN (OR 5.36, 95% CI 1.95–14.73, <i>p</i> = 0.001). <b><i>Conclusions:</i></b> Our results show that high IOP affects 12.5% of 8-year-old school children and appears to be associated with high BP related to a high BMI.

Intraocular Pressure Over the Clinical Range of Blood Pressure: Blue Mountains Eye Study Findings

2005 ◽  
Vol 140 (1) ◽  
pp. 131-132 ◽  
Author(s):  
Paul Mitchell ◽  
Anne J. Lee ◽  
Jie Jin Wang ◽  
Elena Rochtchina
Keyword(s):  
Blood Pressure ◽  
Intraocular Pressure ◽  
Blue Mountains ◽  
Blue Mountains Eye Study

Diurnal Blood Pressure Variation in Quadriplegic Chronic Spinal Cord Injury Patients

1991 ◽  
Vol 80 (3) ◽  
pp. 271-276 ◽  
Author(s):  
Henry Krum ◽  
William J. Louis ◽  
Douglas J. Brown ◽  
Graham P. Jackman ◽  
Laurence G. Howes
Keyword(s):  
Blood Pressure ◽  
Spinal Cord ◽  
Heart Rate ◽  
Spinal Cord Injury ◽  
Ambulatory Monitoring ◽  
Pressure Variation ◽  
Night Time ◽  
Cord Injury ◽  
Blood Pressure Variation ◽  
Neurologically Intact

1. Measurement of blood pressure and heart rate over a 24 h period was peformed in 10 quadriplegic spinal cord injury patients and 10 immobilized, neurologically intact orthopaedic subjects by using the Spacelabs 90207 automated ambulatory monitoring system. 2. Systolic and diastolic blood pressure fell significantly at night in orthopaedic subjects but not in quadriplegic patients, and night-time blood pressures were similar in both groups. 3. Cumulative summation of differences from a reference value (cusum analysis) confirmed a markedly diminished diurnal blood pressure variation in the quadriplegic patients. 4. These findings could not be accounted for on the basis of blood pressure variations during chronic postural change. 5. Heart rate fell significantly at night in both groups. 6. The findings suggest that the increase in blood pressure during waking hours in neurologically intact subjects is a consequence of a diurnal variation in sympathetic activity (absent in quadriplegic patients with sympathetic decentralization) which is independent of changes in physical activity.

Sign in / Sign up

Export Citation Format

Share Document