Risk Factors Associated With Laboratory-confirmed Bloodstream Infections in a Tertiary Neonatal Intensive Care Unit

2014 ◽  
Vol 33 (10) ◽  
pp. 1027-1032 ◽  
Author(s):  
Michael A. Padula ◽  
Maya L. Dewan ◽  
Samir S. Shah ◽  
Amy M. Padula ◽  
Lakshmi Srinivasan ◽  
...  
2001 ◽  
Vol 22 (6) ◽  
pp. 357-362 ◽  
Author(s):  
Ludo M. Mahieu ◽  
Jozef J. De Dooy ◽  
Aimé O. De Muynck ◽  
Guillaume Van Melckebeke ◽  
Margareta M. Ieven ◽  
...  

AbstractObjective:To identify risk factors and describe the microbiology of catheter exit-site and hub colonization in neonates.Design:During a period of 2 years, we prospectively investigated 14 risk factors for catheter exit-site and hub colonization in 862 central venous catheters in a cohort of 441 neonates. Cultures of the catheter exit-site and hub were obtained using semiquantitative techniques at time of catheter removal.Setting:A neonatal intensive care unit at a university hospital.Results:Catheter exit-site colonization was found in 7.2% and hub colonization in 5.3%. Coagulase-negative staphylococci were predominant at both sites. Pathogenic flora were found more frequently at the catheter hub (36% vs 14%;P<.05). Through logistic regression, factors associated with exit-site colonization were identified as umbilical insertion (odds ratio [OR], 8.1; 95% confidence interval [CI95], 2.35-27.6;P<.001), subclavian insertion (OR, 54.6; CI95, 12.2-244;P<.001), and colonization of the catheter hub (OR, 8.9; CI95,3.5-22.8;P<.001). Catheter-hub colonization was associated with total parenteral nutrition ([TPN] OR for each day of TPN, 1.056; CI95,1.029-1.083;P<.001) and catheter exit-site colonization (OR, 6.11; CI95, 2.603-14.34;P<.001). No association was found between colonization at these sites and duration of catheterzation and venue of insertion, physician's experience, postnatal age and patient's weight, ventilation, steroids or antibiotics, and catheter repositioning.Conclusion:These data support that colonization of the catheter exit-site is associated with the site of insertion and colonization of the catheter hub with the use of TPN. There is a very strong association between colonization at both catheter sites.


2016 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Sabahattin Ertugrul ◽  
Fesih Aktar ◽  
Ilyas Yolbas ◽  
Ahmet Yilmaz ◽  
Bilal Elbey ◽  
...  

Author(s):  
Margaret Jaraiseh Abcarius ◽  
Berly Alejandra Zambrano Bravo ◽  
Manuel Eugenio Morocho-Cayamcela ◽  
Ana Belén Tulcanaza-Prieto

Introducción: El peso al nacer es uno de los principales indicadores pronóstico de mortalidad neonatal, en el que influyen factores asociados con la madre, el neonato, y también con las características socioeconómicas del núcleo familiar. Los factores de riesgo implican comorbilidades al momento del nacimiento, por lo que, la intervención adecuada y el oportuno acceso a los servicios de salud constituyen elementos primordiales para la reducción de la mortalidad neonatal. Objetivo: establecer los factores de riesgo asociados a la mortalidad y peso al nacer de pacientes neonatos, de la Unidad de Cuidados Intensivos Neonatales del Hospital Pediátrico Baca Ortiz. Métodos: Se realizó una investigación de diseño observacional, transversal de tipo descriptivo que con una muestra de 204 recién nacidos ingresados en la Unidad de Cuidados Intensivos Neonatales del Hospital Pediátrico Baca Ortiz en la ciudad de Quito, Ecuador, durante el año 2019.  Resultados: El peso al nacimiento tiene una asociación lineal negativa significativa con la mortalidad neonatal, siendo los neonatos de género masculino los más susceptibles a fallecer. También, existe mayor frecuencia de mortalidad neonatal en las madres que residen en el área urbana de la sierra ecuatoriana. Conclusiones: El peso al nacer es una variable de gran influencia en la salud y supervivencia infantil, debido a que los datos epidemiológicos muestran que un niño que nace con un peso por debajo de los límites normales tiene un mayor riesgo de fallecer, en comparación con los niños nacidos con un peso dentro del rango considerado normal.   Palabras clave: Mortalidad infantil, factores de riesgo, recién nacido de bajo peso, enfermería neonatal, mortalidad neonatal.  Abstract Introduction: Birth weight is one of the main prognostic indicators of neonatal mortality, which is influenced by factors associated with the mother, the neonate, and the socioeconomic characteristics of the family. Moreover, the risk factors imply comorbidities at birth. Therefore, adequate intervention and timely access to health services constitute essential elements to reduce neonatal mortality. Objective: establish the risk factors associated with mortality and birth weight of neonatal patients, from the Neonatal Intensive Care Unit of the Baca Ortiz Pediatric Hospital. Methods: An observational, cross-sectional, descriptive research was carried out with a sample of 204 newborns admitted to the Neonatal Intensive Care Unit of the Baca Ortiz Pediatric Hospital in the city of Quito, Ecuador, during the year 2019. Results: The birth weight shows a significant negative linear association with neonatal mortality, where the male infants are the most susceptible to death. Furthermore, there is a higher frequency of neonatal mortality in mothers who live in the urban area of ​​the Ecuadorian highlands. Conclusions: The birth weight is a highly influential variable for child health and survival since epidemiological data show that a newborn with a weight below the range considered normal, has a higher risk of death as compared to children with a normal weight. Keywords: Infant mortality, risk factors, low birth weight, neonatal nursing, neonatal mortality.


2021 ◽  
Vol 2 (12) ◽  
pp. 1183-1186
Author(s):  
Ilse Lizeth Villegas-Velasquez ◽  
Luz Irene Pascual-Mathey ◽  
Olga Lidia Valenzuela-Limon ◽  
Patricia Elisa Molina-Prior ◽  
Jose Locia-Espinoza ◽  
...  

Neonatal Sepsis (NS) is a systemic infection caused by bacteria, fungi, or viruses during the first month of life. Although various studies have identified the factors associated with NS, it is a public health problem due to its high morbidity and mortality. The study aimed to identify the risk factors associated with neonatal sepsis in the Neonatal Intensive Care Unit (NICU) of a tertiary hospital in Mexico. A case-control study was carried out using records of neonates (with sepsis 39 and without sepsis 39) from January to December 2017. The risk factors studied were the sociodemographic and clinical characteristics of the mother and clinics of the neonate. The data were analyzed using the Chi2 test, Fisher's exact test, Student's t-test, and the Odds Ratio (OR). The risk factors associated with NS were gestational age (OR 0.77, CI 95% = 0.64-0.91, p = 0.004), newborn weight (OR 0.45, CI95% = 0.23-0.86, p = 0.017) and days of hospital stay (OR 1.06, CI95% = 1.02-1.10, p = 0.0014). The mother's sociodemographic and clinical factors were not associated with NS. Risk factors associated with NS were gestational age, newborn weight, and days of hospital stay.


2018 ◽  
Vol 33 (4) ◽  
pp. 93-100
Author(s):  
Sharita Rameshwarnath ◽  
Saloshni Naidoo

Background: Nosocomial infections are one of the main causes of neonatal morbidity and mortality in low- and middle-income countries. The neonatal intensive care unit is a suitable environment for disseminating infections. The aim of this study was to identify risk factors associated with having a nosocomial infection in the neonatal intensive care unit at Mahatma Gandhi Memorial hospital between 2014 and 2015.Methods: An observational, analytical case-control study was conducted at the neonatal intensive care unit at Mahatma Gandhi Memorial hospital in 2017 following ethical approval (BE336/16). A retrospective review of medical records for a sample size of 144 cases and 144 matched controls from 2014 to 2015 was analysed. Descriptive statistics were presented and multivariate conditional logistic regression was used to determine associations between the independent variables and having a nosocomial infection.Results: A total of 144 neonates developed nosocomial infections as proven by positive cultures with Klebsiella pneumoniae being most frequent (n = 60; 41.67%). On multivariate logistic regression analysis, multiple deliveries, low birth weight, respiratory distress, prematurity, neonatal jaundice, hyaline membrane disease, the use of total parenteral nutrition, blood transfusion and surfactant administration, immediate use of oxygen and intravenous fluid and central line insertion were significantly associated with having a nosocomial infection (p ≤ 0.001).Conclusion: Neonatal-related factors and treatment modalities were identified as factors that increased the risk for nosocomial infections. A review of treatment modalities and related infection prevention and control in neonatal management are the key to prevention, early detection and management of nosocomial infections.


2017 ◽  
Vol 5 (1) ◽  
pp. 28-33
Author(s):  
Jyoti Baba Shrestha ◽  
Reena Yadav ◽  
Jeevan Kumar Shrestha ◽  
Laxman Shrestha ◽  
Raman Prasad Sah

Background: Retinopathy of prematurity is a vascular retinal disease that can cause blindness in premature new born babies. Several risk factors are associated with the incidence of ROP. Information and data on risk factors associated with ROP in context to Nepalese population is scarcely documented in literature.Objectives: The purpose of this study was to evaluate the risk factors of retinopathy of prematurity in premature infants admitted in the neonatal intensive care unit of Tribhuvan University Teaching Hospital.Methods: Neonates with gestational age of 36 weeks or less and birth weight of 2000 gram or less admitted to neonatal intensive care unit (NICU), during 2013 to 2015 were screened for retinopathy of prematurity. Risk factors and severity of retinopathy of prematurity were evaluated. The initial examination was carried out at 4-6 weeks after birth by indirect ophthalmoscope and retinopathy of prematurity positive and negative infants were compared subsequently. The Chisquare and independent t-tests were used for statistical analysis. A p value less than 0.05 was considered statistically signifi cant.Results: The incidence of retinopathy of prematurity was 22.6% and severe retinopathy of prematurity requiring treatment was observed in 3.2% of 93 neonates who had eye examinations. There was a signifi cant relationship between the occurrence of ROP and birth weight (p=0.000), gestational age (p=0.000), duration of oxygen therapy (p=0.009) and sepsis (p=0.002). However, insignifi cant relationship was observed between the occurrence of retinopathy of prematurity and gender, type of delivery, multiple gestation, premature rupture of foetal membrane, respiratory distress syndrome and hyperbilirubinaemia.Conclusion: The risk factors contributing to development of retinopathy of prematurity showed signifi cant relationship with immaturity, duration of oxygen supplementation and septicaemia.Journal of Kathmandu Medical CollegeVol. 5, No. 1, Issue 15, Jan.-Mar., 2016,page: 28-33


Sign in / Sign up

Export Citation Format

Share Document