scholarly journals Immune Response Persistence and Safety of a Booster Dose of the Tetravalent Dengue Vaccine in Adolescents and Adults Who Previously Completed the 3-dose Schedule 4–5 Years Earlier in Latin America

2020 ◽  
Vol 39 (10) ◽  
pp. 961-968 ◽  
Author(s):  
Diana Coronel ◽  
Enid J. García-Rivera ◽  
Doris Maribel Rivera ◽  
José Luis Arredondo-García ◽  
Reynaldo Dietze ◽  
...  
Keyword(s):  
Immune Response ◽  
Latin America ◽  
Booster Dose ◽  
Dose Schedule ◽  
Dengue Vaccine ◽  
Adolescents And Adults ◽  
Response Persistence

scholarly journals Dengue Vaccine Booster in Healthy Adolescents and Adults in Latin America

2019 ◽  
Vol 38 (5) ◽  
pp. e90-e95 ◽  
Author(s):  
Diana Coronel ◽  
Enid J. García-Rivera ◽  
Maribel Rivera ◽  
José Luis Arredondo-García ◽  
Reynaldo Dietze ◽  
...  
Keyword(s):  
Latin America ◽  
Dengue Vaccine ◽  
Vaccine Booster ◽  
Adolescents And Adults

scholarly journals Persistence of Antibody in Adolescents and Adults After a Third, Booster, Dose of Poliomyelitis Vaccine

BMJ ◽  
1960 ◽  
Vol 1 (5187) ◽  
pp. 1689-1691 ◽  
Author(s):  
E. J. C. Kendall ◽  
T. S. L. Beswick ◽  
A. Miller ◽  
J. Oh. Tobin
Keyword(s):  
Booster Dose ◽  
Poliomyelitis Vaccine ◽  
Adolescents And Adults

scholarly journals PARACOCCIDIOIDOMYCOSIS: CHALLENGES IN THE DEVELOPMENT OF A VACCINE AGAINST AN ENDEMIC MYCOSIS IN THE AMERICAS

2015 ◽  
Vol 57 (suppl 19) ◽  
pp. 21-24 ◽  
Author(s):  
Carlos. P. TABORDA ◽  
M.E. URÁN ◽  
J. D. NOSANCHUK ◽  
L.R. TRAVASSOS
Keyword(s):  
Immune Response ◽  
Latin America ◽  
Monoclonal Antibodies ◽  
Clinical Practice ◽  
Therapeutic Vaccines ◽  
Endemic Mycosis ◽  
Paracoccidioides Spp ◽  
Important Means ◽  
Cellular Immune ◽  
Stimulation Of

SUMMARYParacoccidioidomycosis (PCM), caused by Paracoccidioides spp, is an important endemic mycosis in Latin America. There are two recognized Paracoccidioides species, P. brasiliensis and P. lutzii, based on phylogenetic differences; however, the pathogenesis and disease manifestations of both are indistinguishable at present. Approximately 1,853 (~51,2%) of 3,583 confirmed deaths in Brazil due to systemic mycoses from 1996-2006 were caused by PCM. Antifungal treatment is required for patients with PCM. The initial treatment lasts from two to six months and sulfa derivatives, amphotericin B, azoles and terbinafine are used in clinical practice; however, despite prolonged therapy, relapses are still a problem. An effective Th1-biased cellular immune response is essential to control the disease, which can be induced by exogenous antigens or modulated by prophylactic or therapeutic vaccines. Stimulation of B cells or passive transference of monoclonal antibodies are also important means that may be used to improve the efficacy of paracoccidioidomycosis treatment in the future. This review critically details major challenges facing the development of a vaccine to combat PCM.

scholarly journals Effect of a booster-dose of rabies vaccine on the duration of virus neutralizing antibody titers in bovines

1998 ◽  
Vol 31 (4) ◽  
pp. 367-371 ◽  
Author(s):  
Avelino Albas ◽  
Paulo Eduardo Pardo ◽  
Albério Antonio Barros Gomes ◽  
Fernanda Bernardi ◽  
Fumio Honma Ito
Keyword(s):  
Immune Response ◽  
Neutralizing Antibodies ◽  
Booster Dose ◽  
Neutralization Test ◽  
Neutralizing Antibody ◽  
Rabies Vaccine ◽  
Western Region ◽  
Humoral Immune ◽  
Paulo State ◽  
Antibody Titers

Humoral immune response using inactivated rabies vaccine was studied in 35 nelore cross-bred bovines of western region of São Paulo state. Ninety days after vaccination, 13 (92.8%) animals presented titers 30.5IU/ml, through mouse neutralization test. After 180 days, 9 (64.3%) sera showed titers 30.5IU/ml, after 270 days, only one (7.1%) showed a titer of 0.51IU/ml, and after 360 days, all animals showed titers < 0.5IU/ml. Group of animals receiving booster dose 30 days after vaccination presented, two months after, all with titers > 0.5IU/ml. At 180 days, 17 (80.9%) sera presented titers > 0.5IU/ml; at 270 days, 15 (71.4%), with titers 30.5IU/ml and at 360 days, 4 (19.0%), with titers 30.5IU/ml. Booster-dose ensured high levels of neutralizing antibodies for at least three months, and 240 days after revaccination, 71.4% of animals were found with titers 30.5IU/ml.

scholarly journals Consequence of HIV and HCV co-infection on host immune response, persistence and current treatment options

VirusDisease ◽  
2018 ◽  
Vol 29 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Sayed Sartaj Sohrab ◽  
Mohd Suhail ◽  
Ashraf Ali ◽  
Ishtiaq Qadri ◽  
Steve Harakeh ◽  
...  
Keyword(s):  
Immune Response ◽  
Treatment Options ◽  
Host Immune Response ◽  
Current Treatment ◽  
Response Persistence
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