scholarly journals Consequence of HIV and HCV co-infection on host immune response, persistence and current treatment options

VirusDisease ◽  
2018 ◽  
Vol 29 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Sayed Sartaj Sohrab ◽  
Mohd Suhail ◽  
Ashraf Ali ◽  
Ishtiaq Qadri ◽  
Steve Harakeh ◽  
...  
2020 ◽  
Vol 6 (1) ◽  
pp. 25 ◽  
Author(s):  
Tyler G. Normile ◽  
Kyle McEvoy ◽  
Maurizio Del Poeta

Invasive fungal infections pose an increasing threat to human hosts, especially in immunocompromised individuals. In response to the increasing morbidity and mortality of fungal infections, numerous groups have shown great strides in uncovering novel treatment options and potential efficacious vaccine candidates for this increasing threat due to the increase in current antifungal resistance. Steryl glycosides are lipid compounds produced by a wide range of organisms, and are largely understudied in the field of pathogenicity, especially to fungal infections. Published works over the years have shown these compounds positively modulating the host immune response. Recent advances, most notably from our lab, have strongly indicated that steryl glycosides have high efficacy in protecting the host against lethal Cryptococcal infection through acting as an immunoadjuvant. This review will summarize the keystone studies on the role of steryl glycosides in the host immune response, as well as elucidate the remaining unknown characteristics and future perspectives of these compounds for the host–fungal interactions.


2010 ◽  
Vol 1 (1) ◽  
Author(s):  
AO Wellington ◽  
OO Oladipo ◽  
OA Chimere ◽  
TO Oladele ◽  
CC Anunobi ◽  
...  

2012 ◽  
Vol 21 (3) ◽  
pp. 75-84
Author(s):  
Venkata Vijaya K. Dalai ◽  
Jason E. Childress ◽  
Paul E Schulz

Dementia is a major public health concern that afflicts an estimated 24.3 million people worldwide. Great strides are being made in order to better diagnose, prevent, and treat these disorders. Dementia is associated with multiple complications, some of which can be life-threatening, such as dysphagia. There is great variability between dementias in terms of when dysphagia and other swallowing disorders occur. In order to prepare the reader for the other articles in this publication discussing swallowing issues in depth, the authors of this article will provide a brief overview of the prevalence, risk factors, pathogenesis, clinical presentation, diagnosis, current treatment options, and implications for eating for the common forms of neurodegenerative dementias.


2001 ◽  
Vol 13 (4) ◽  
pp. 233-237 ◽  
Author(s):  
Roger Boshes ◽  
Theo Manschreck ◽  
Jean Desrosiers ◽  
Steven Candela ◽  
Meredith Hanrahan-Boshes

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