Second Primary Neoplasms in Patients With Sebaceous Carcinoma of the Eyelid

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Abanoob F. Tadrosse ◽  
Marina F. Tadrosse ◽  
Bishoy M. Ezzat ◽  
Dina M. Sadek ◽  
Paul D. Langer
Keyword(s):  
Sebaceous Carcinoma ◽  
Second Primary ◽  
Second Primary Neoplasms ◽  
Primary Neoplasms

Primary Malignant Neoplasms Associated with Chronic Lymphocytic Leukemia

1980 ◽  
Vol 66 (4) ◽  
pp. 431-438 ◽  
Author(s):  
Armando Santoro ◽  
Franco Rilke ◽  
Franca Franchi ◽  
Silvio Monfardini
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Alkylating Agents ◽  
Malignant Lesion ◽  
Lymphocytic Leukemia ◽  
Second Primary ◽  
Malignant Neoplasms ◽  
Primary Malignancy ◽  
Second Primary Neoplasms ◽  
Primary Neoplasms ◽  
Cellular And Humoral Immunity

Over the past 2 decades there has been an almost exponential increase in the frequency with which cases of leukemia associated with another primary malignant lesion have been reported. In this study we reported the occurrence of a second primary neoplasm in 82 consecutive cases of chronic lymphocytic leukemia (CLL) admitted to the Istituto Nazionale Tumori of Milan from September 1962 to December 1978. In 16 of these (19.5%), an associated neoplasm was diagnosed subsequently (8 cases) or concurrently (8 cases) to CLL. Head and neck carcinomas and breast cancer had the highest incidence (5 and 3 cases, respectively). The results of this study further support the hypothesis that patients with CLL are prone to develop subsequent cancer. The defective cellular and humoral immunity in CLL may have an etiological role in the development of an additional primary malignancy. Although alkylating agents are known carcinogens in experimental animals and man, our results support the lack of a correlation between treatment with alkylating agents and incidence of second primary neoplasms, as demonstrated by Greene et al. (10).

Second Primary Neoplasms Following a Diagnosis of Breast Cancer

2016 ◽  
pp. 213-234
Author(s):  
Felicity Paterson ◽  
Susannah Stanway ◽  
Lone Gothard ◽  
Navita Somaiah
Keyword(s):  
Breast Cancer ◽  
Second Primary ◽  
Second Primary Neoplasms ◽  
Primary Neoplasms

CT and MRI Features of Recurrent Tumors and Second Primary Neoplasms in Pediatric Patients with Retinoblastoma

2003 ◽  
Vol 181 (3) ◽  
pp. 879-884 ◽  
Author(s):  
Ukihide Tateishi ◽  
Tadashi Hasegawa ◽  
Kunihisa Miyakawa ◽  
Minako Sumi ◽  
Noriyuki Moriyama
Keyword(s):  
Pediatric Patients ◽  
Second Primary ◽  
Second Primary Neoplasms ◽  
Recurrent Tumors ◽  
Mri Features ◽  
Primary Neoplasms ◽  
Ct And Mri

scholarly journals Second Primary Neoplasms in Patients With Laryngeal Carcinoma

2000 ◽  
Vol 110 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Angelos C. Nikolaou ◽  
Constantinos D. Markou ◽  
Dimitrios G. Petridis ◽  
Ioannis C. Daniilidis
Keyword(s):  
Laryngeal Carcinoma ◽  
Second Primary ◽  
Second Primary Neoplasms ◽  
Primary Neoplasms

Synchronous Second Primary Neoplasms Detected by Initial Staging F-18 FDG PET/CT Examination in Patients With Non-Hodgkin Lymphoma

2011 ◽  
Vol 36 (7) ◽  
pp. 509-512 ◽  
Author(s):  
Tomáš Papajík ◽  
Miroslav Mysliveček ◽  
Zuzana Šedová ◽  
Eva Buriánková ◽  
Vít Procházka ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Fdg Pet ◽  
Second Primary ◽  
Ct Examination ◽  
Non Hodgkin Lymphoma ◽  
Second Primary Neoplasms ◽  
Pet Ct ◽  
Primary Neoplasms ◽  
Fdg Pet Ct ◽  
Initial Staging

scholarly journals Cancer predisposition syndromes as risk factor for early second primary neoplasms after childhood cancer - a national cohort study

2020 ◽  
Author(s):  
Nicolas Waespe ◽  
Fabien Naomi Belle ◽  
Shelagh Redmond ◽  
Christina Schindera ◽  
Ben Daniel Spycher ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Childhood Cancer ◽  
Cancer Patients ◽  
Cumulative Incidence ◽  
Cancer Predisposition ◽  
Second Primary ◽  
Hematopoietic Stem ◽  
Second Primary Neoplasms ◽  
Primary Neoplasms

Background: Childhood cancer patients are at increased risk of second primary neoplasms (SPNs). We assessed incidence and risk factors for early SPNs with a focus on cancer predisposition syndromes (CPSs). Patients and methods: This cohort study used data from the Swiss Childhood Cancer Registry. We included patients with first primary neoplasms (FPN) until age 21 years from 1986 to 2015 and identified SPNs occurring before age 21. We calculated standardized incidence ratios (SIR) and absolute excess risks (AER) using Swiss population cancer incidence data and cumulative incidence of SPNs. We calculated hazard ratios (HR) of risk factors for SPNs using Fine and Gray competing risk regression. Results: Among 8,074 childhood cancer patients, 304 (4%) were diagnosed with a CPS and 94 (1%) developed early SPNs. The incidence of SPNs was more than 10-fold increased in childhood cancer patients compared to neoplasms in the general population (SIR 10.6, 95%-confidence interval [CI] 8.7-13.1) and the AER was 179/100,000 person-years (CI 139-219). Cumulative incidence of SPNs 20 years after FPN diagnosis was 23% in patients with CPSs and 3% in those without. Risk factors for SPNs were CPSs (HR 7.8, CI 4.8-12.7), chemotherapy (HR 2.2, CI 1.1-4.6), radiotherapy (HR 1.9, CI 1.2-2.9), hematopoietic stem cell transplantation (HR 1.8, CI 1-3.3), and older age (15-20 years) at FPN diagnosis (HR 1.9, CI 1.1-3.2). Conclusion: CPSs are associated with a high risk of SPNs before age 21 years. Identification of CPSs is important for appropriate cancer surveillance and targeted screening.

scholarly journals Bronchial carcinoid tumors: second primary neoplasms and outcomes of surgical treatment

2019 ◽  
Vol 45 (5) ◽  
Author(s):  
Jefferson Luiz Gross ◽  
Marcel Adalid Tapia Vega ◽  
Guilherme Strambi Frenhi ◽  
Silvio Melo Torres ◽  
Antonio Hugo José Froes Marques Campos ◽  
...  
Keyword(s):  
Disease Free Survival ◽  
Good Prognosis ◽  
Carcinoid Tumors ◽  
Second Primary ◽  
Bronchial Carcinoid ◽  
Ki 67 ◽  
Typical Carcinoid ◽  
Second Primary Neoplasms ◽  
Kaplan Meier ◽  
Primary Neoplasms

ABSTRACT Objective: To analyze determinants of prognosis in patients with bronchial carcinoid tumors treated surgically and the potential concomitance of such tumors with second primary neoplasms. Methods: This was a retrospective analysis of 51 bronchial carcinoid tumors treated surgically between 2007 and 2016. Disease-free survival (DFS) was calculated by the Kaplan-Meier method, and determinants of prognosis were evaluated. Primary neoplasms that were concomitant with the bronchial carcinoid tumors were identified by reviewing patient charts. Results: The median age was 51.2 years, 58.8% of the patients were female, and 52.9% were asymptomatic. The most common histology was typical carcinoid (in 80.4%). Five-year DFS was 89.8%. Ki-67 expression was determined in 27 patients, and five-year DFS was better among the patients in whom Ki-67 expression was ≤ 5% than among those in whom it was > 5% (100% vs. 47.6%; p = 0.01). Concomitant primary neoplasms were observed in 14 (27.4%) of the 51 cases. Among the concomitant primary neoplasms that were malignant, the most common was lung adenocarcinoma, which was observed in 3 cases. Concomitant primary neoplasms were more common in patients who were asymptomatic and in those with small tumors. Conclusions: Surgical resection is the mainstay treatment of bronchopulmonary carcinoid tumors and confers a good prognosis. Bronchial carcinoid tumors are likely to be accompanied by second primary neoplasms.

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