Pulmonary Actinomycosis as the Masquerader of Pulmonary Tuberculosis in a Young Male With Achalasia Cardia

Stevens-Johnson syndrome (SJS) is a rare, serious disorder and may be life threatening affecting mainly mucocutaneous tissues. It is a type of generalised, multisystemic hypersensitivity reaction directly linked to the drug intake. It is one of the few serious adverse effects of drugs involving skin and mucous membranes which are characterised by rash, bullae and blisters spread on skin, mucous membranes, swelling with erosive lesions on lips and face and hyperpigmentation. Normally, SJS is a self-resolving condition but it has potential to be converted into life-threatening disease. Here, we describe and present a case series of SJS inflicted by rifampicin and allopurinol. First one is a 28-year-old-female and second case is a 50-year-old male, both received rifampicin for pulmonary tuberculosis. Third patient is a 22-year-old young male taken allopurinol for hyperuricemia. All these patients noticed a severe skin reaction which is a part of erythema multiforme spectrum. Causality assessment was done in these patients with the help of Naranjo’s algorithm and diagnosed as cases of SJS.

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Haemoptysis in a patient of achalasia cardia: pulmonary actinomycosis, not tuberculosis

BMJ Case Reports ◽

10.1136/bcr.09.2009.2287 ◽

2010 ◽

Vol 2010 (mar04 1) ◽

pp. bcr0920092287-bcr0920092287

Author(s):

A. M. Wani ◽

W. M. Hussain ◽

A. A. Banjar ◽

W. H. A. Miamini ◽

A. M. Khoujah ◽

...

Keyword(s):

Achalasia Cardia ◽

Pulmonary Actinomycosis

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Comparison of Tuberculin Skin Test and Quantiferon-TB Gold in-Tube Assay in Young Male Patients with Pulmonary Tuberculosis

Turkiye Klinikleri Journal of Medical Sciences ◽

10.5336/medsci.2009-16604 ◽

2011 ◽

Vol 31 (3) ◽

pp. 534-540

Author(s):

Faruk ÇİFTÇİ ◽

Ogün SEZER ◽

Hatice KAYA ◽

Ergun TOZKOPARAN ◽

Erkan BOZKANAT ◽

...

Keyword(s):

Pulmonary Tuberculosis ◽

Tuberculin Skin Test ◽

Skin Test ◽

Young Male ◽

Male Patients

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Ultrastructural Study of Human Testicular Biopsies in Infertility

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100090762 ◽

1976 ◽

Vol 34 ◽

pp. 156-157

Author(s):

Shirley Siew ◽

Philip Troen ◽

Howard R. Nankin

Keyword(s):

Electron Microscopy ◽

Transmission Electron Microscopy ◽

Basement Membrane ◽

Leydig Cells ◽

Clinical Evidence ◽

Young Male ◽

Germinal Epithelium ◽

Transmission Electron ◽

Age Range ◽

Male Subjects

Testicular biopsies were obtained from six young male subjects (age range 24-33) who complained of infertility and who had clinical evidence of oligospermia. This was confirmed on histological examination which showed a broad spectrum from profound hypospermatogenesis to relatively normal appearing germinal epithelium. Thickening of the tubular walls was noted in half of the cases and slight peritubular fibrosis in one. The Leydig cells were reported as normal or unremarkable.Transmission electron microscopy showed that the thickening of the supporting tissue of the germinal epithelium was caused more by an increase in the thickness of the layers of the lamina propria than of the tubular wall itself. The changes in the basement membrane of the tubular wall consisted mostly of a greater degree of infolding into the tubule and some reduplication which gave rise to a multilayered appearance.

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Remission of Recurrent Cochlear Hydrops Associated With Bromocriptine Treatment for Macroprolactinoma

American Journal of Audiology ◽

10.1044/2019_aja-18-0191 ◽

2019 ◽

Vol 28 (3) ◽

pp. 548-552

Author(s):

Andro Košec ◽

Ivan Kruljac ◽

Jakov Ajduk

Keyword(s):

Dopamine Receptors ◽

Male Patient ◽

Endolymphatic Hydrops ◽

Young Male ◽

Oral Steroid ◽

Case Description ◽

Diuretic Treatment ◽

Potential Therapeutic Role ◽

Transient Improvement ◽

Systemic Glucocorticoids

Objective Current recommendations for cochlear hydrops treatment include systemic glucocorticoids and diuretics. Cochlear cells express dopamine receptors, although their role is unknown in the pathophysiology of cochlear hydrops. Case Description We report the case of remission of recurrent right-sided cochlear hydrops in a young male patient treated with bromocriptine due to pituitary macroprolactinoma. Transient improvement was observed after oral steroid and diuretic treatment, but cochlear hydrops recurred until the dose of bromocriptine was increased to 10 mg daily. Conclusion Bromocriptine may stimulate dopamine receptors in cochlear cells with potential therapeutic role in patients with cochlear hydrops. There are no widely accepted and effective treatments for endolymphatic hydrops, and identifying potential new and efficacious therapeutics is of high relevance.

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