Maternal Occupation and Risk for Low Birth Weight Delivery: Assessment Using State Birth Registry Data

2008 ◽  
Vol 50 (3) ◽  
pp. 306-315 ◽  
Author(s):  
John D. Meyer ◽  
Ginger H. Nichols ◽  
Nicholas Warren ◽  
Susan Reisine
2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Abdulbari Bener ◽  
Khalil M. K. Salameh ◽  
Mohammad T. Yousafzai ◽  
Najah M. Saleh

Objective. The objective of the study was to examine the pattern of low birth weight LBW, maternal complications, and its related factors among Arab women in Qatar. Design. This is a prospective hospital-based study. Setting. The study was carried out in Women’s Hospital, Doha. Subjects and Methods. Pregnant women in their third trimester were identified in the log book of Women’s Hospital and recruited into the study during first week of January 2010 to July 2011. Only 1674 (out of 2238) Arab women (74.7%) consented to participate in this study. Data on clinical and biochemistry parameters were retrieved from medical records. Follow-up data on neonatal outcome was obtained from labor room register. Results. The incidence of LBW (<2500 g) was 6.7% among Arab women during 2010 in Qatar. Distribution of gestational diabetes mellitus (GDM), antepartum hemorrhage (APH), maternal anemia, premature rupture of membrane (PROM), maternal occupation, parity, sheesha smoking, and parental consanguinity were significantly different (P<0.05) between mothers of LBW and normal birth weight NBW (≥2500 g) babies. Multivariable logistic regression analysis revealed that previous LBW, consanguinity, parity, smoking shesha, GDM, APH, anemia, PROM, maternal occupation, and housing condition were significantly associated with LBW adjusting for gestational age. Conclusion. Maternal complications such as GDM, APH, anemia, PROM, and smoking shesha during pregnancy are significantly increasing the risk of LBW outcome. Screening and prompt treatment for maternal complications and health education for smoking cessation during routine antenatal visits will help in substantial reduction of LBW outcome.


2018 ◽  
Vol 23 (suppl_1) ◽  
pp. e38-e38
Author(s):  
Charlene Nielsen ◽  
Carl Amrhein ◽  
Jesus Serrano Lomelin ◽  
Osmar Zaiane ◽  
Alvaro Osornio Vargas

Abstract BACKGROUND Disorders related to short gestation and low birth weight are the 2nd cause of infant death in Canada and have been increasing, especially in Alberta. Individual maternal risks are important but environmental exposures during pregnancy may restrict fetal growth. This contributes to small for gestational age (SGA: < tenth percentile weight for pregnancy duration) and low birth weight at term (LBWT: <2500 grams at ≥37 weeks-gestation). OBJECTIVES We examined the spatial-temporal patterns of SGA and LBWT with patterns of pollutants around conception, middle trimester, and birth. DESIGN/METHODS We aggregated postal code locations of mothers’ residences from the 2006–2012 birth registry in to space-time bins to analyze emerging hot spots. We applied the space-time pattern analysis on 70 industrial chemical emissions from the National Pollutant Release Inventory (NPRI) in estimated three month intervals. Then we statistically associated the classified patterns of SGA/LBWT with the pollutant patterns using the kappa statistic to determine how much the hot spot categories agree. The difference between kappa values indicated which trimester would be more important for which chemical. RESULTS ​There was an increasing trend for SGA (consecutive hot spots) and for LBWT (sporadic hot spots) in major urban centers. There was an increasing trend for 15 chemicals (varying hot spots). 28 chemical patterns had a kappa index greater than 0.2 with SGA or LBWT patterns. Although there is poor agreement between the space-time patterns, the maximum kappa values occurred mostly with LBWT and around birth. CONCLUSION Spatial-temporal patterns of chemicals identified in published literature (e.g. particulate matter and gases) agreed more with timing around conception; however, there were additional pollutants identified during the birth trimester. Our research is moving us toward a better understanding of the spatial-temporal link between environment and early health.


2014 ◽  
Vol 24 (1-2) ◽  
Author(s):  
Lydia E. Farrell ◽  
Susan E. Hiby ◽  
Richard Apps ◽  
Olympe Chazara ◽  
Lill Trogstad ◽  
...  

Pregnancies resulting in very small or very large babies are at higher risk of obstetric complications with increased morbidity for both mother and baby. Using data from the Medical Birth Registry of Norway we have shown how human birth weight is still subject to stabilizing selection. Particular combinations of maternal/fetal immune genes have been implicated in pregnancies resulting in a low birth weight baby (&lt;5th birth weight centile). More specifically, an inhibitory maternal <em>KIRAA</em> genotype with a paternally derived fetal <em>HLA-C2</em> ligand. At the other end of the birth weight spectrum the presence of an activating maternal <em>KIR2DS1</em> gene is associated with increased birth weight in linear or logistic regression analyses of all pregnancies &gt;5th centile (p=0.005, OR=2.65). Thus, inhibitory maternal <em>KIR</em> combined with fetal <em>HLA-C2</em> is more frequently associated with low birth weight, whereas activating maternal <em>KIR</em> with fetal <em>HLA-C2</em> ligand is associated with increasing birth weight. Our findings using the MoBa cohort have replicated the association of <em>KIR </em>and <em>HLA-C </em>seen in poor placentation, and confirm the importance of maternal/fetal immune gene interactions in determining the outcome of pregnancy.


2011 ◽  
Vol 42 (5) ◽  
pp. 1091-1102 ◽  
Author(s):  
M. Losh ◽  
D. Esserman ◽  
H. Anckarsäter ◽  
P. F. Sullivan ◽  
P. Lichtenstein

BackgroundAutism spectrum disorder (ASD) is a neurodevelopmental disorder of complex etiology. Although strong evidence supports the causal role of genetic factors, environmental risk factors have also been implicated. This study used a co-twin–control design to investigate low birth weight as a risk factor for ASD.MethodWe studied a population-based sample of 3715 same-sex twin pairs participating in the Child and Adolescent Twin Study of Sweden (CATSS). ASD was assessed using a structured parent interview for screening of ASD and related developmental disorders, based on DSM-IV criteria. Birth weight was obtained from medical birth records maintained by the Swedish Medical Birth Registry.ResultsTwins lower in birth weight in ASD-discordant twin pairs (n=34) were more than three times more likely to meet criteria for ASD than heavier twins [odds ratio (OR) 3.25]. Analyses of birth weight as a continuous risk factor showed a 13% reduction in risk of ASD for every 100 g increase in birth weight (n=78). Analysis of the effect of birth weight on ASD symptoms in the entire population (most of whom did not have ASD) showed a modest association. That is, for every 100 g increase in birth weight, a 2% decrease in severity of ASD indexed by scores on the Autism – Tics, attention-deficit hyperactivity disorder (AD/HD), and other Comorbidities (A-TAC) inventory would be expected in the sample as a whole.ConclusionsThe data were consistent with the hypothesis that low birth weight confers risk to ASD. Thus, although genetic effects are of major importance, a non-genetic influence associated with birth weight may contribute to the development of ASD.


2020 ◽  
Author(s):  
Shanshan Wang ◽  
Liren Yang ◽  
Li Shang ◽  
Wenfang Yang ◽  
Cuifang Qi ◽  
...  

Abstract Background: Most studies have shown that maternal age is associated with birth weight. However, the specific relationship between each additional year of maternal age and birth weight remains unclear. The study aimed to analyze the specific association between maternal age and birth weight. Methods: Raw data for all live births from 2015 to 2018 were obtained from the Medical Birth Registry of Xi’an, China. A total of 490143 mother-child pairs with full-term singleton live births and the maternal age ranging from 20 to 40 years old were included in our study. Birth weight, gestational age, birth date of the newborns, maternal birth date, residence and ethnicity were collected. Generalized additive model and two-piece wise linear regression model were used to analyze the specific relationships between maternal age and birth weight, risk of low birth weight, and risk of macrosomia. Results: The relationships between maternal age and birth weight, risk of low birth weight, and risk of macrosomia were nonlinear. Birth weight increased 16.204 g per year when maternal age is less than 24 years old (95%CI: 14.323, 18.086), and increased 12.051g per year when maternal age ranged from 24 to 34 years old (95%CI: 11.609, 12.493), then decreased 0.824g per year (95% CI: -3.112, 1.464). The risk of low birth weight decreased with the increase of maternal age until 36 years old (OR= 0.917, 95%CI: 0.903, 0.932 when maternal age younger than 27 years old; OR= 0.965, 95%CI: 0.955, 0.976 when maternal age ranging from 27 to 36 years old), then increased when maternal age older than 36 years old (OR=1.133, 95%CI: 1.026, 1.250). The risk of macrosomia increased with the increase of maternal age (OR=1.102, 95%CI: 1.075, 1.129 when maternal age younger than 24 years old; OR=1.065, 95%CI: 1.060, 1.071 when maternal age ranged from 24 to 33 years old; OR=1.029, 95%CI: 1.012, 1.046 when maternal age older than 33 years old). Conclusions: For women of childbearing age (20-40 years old), the threshold of maternal age on low birth weight was 36 years old, and the risk of macrosomia increased with the increase of maternal age.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Shanshan Wang ◽  
Liren Yang ◽  
Li Shang ◽  
Wenfang Yang ◽  
Cuifang Qi ◽  
...  

Abstract Background Most studies have shown that maternal age is associated with birth weight. However, the specific relationship between each additional year of maternal age and birth weight remains unclear. The study aimed to analyze the specific association between maternal age and birth weight. Methods Raw data for all live births from 2015 to 2018 were obtained from the Medical Birth Registry of Xi’an, China. A total of 490,143 mother-child pairs with full-term singleton live births and the maternal age ranging from 20 to 40 years old were included in our study. Birth weight, gestational age, neonatal birth date, maternal birth date, residence and ethnicity were collected. Generalized additive model and two-piece wise linear regression model were used to analyze the specific relationships between maternal age and birth weight, risk of low birth weight, and risk of macrosomia. Results The relationships between maternal age and birth weight, risk of low birth weight, and risk of macrosomia were nonlinear. Birth weight increased 16.204 g per year when maternal age was less than 24 years old (95%CI: 14.323, 18.086), and increased 12.051 g per year when maternal age ranged from 24 to 34 years old (95%CI: 11.609, 12.493), then decreased 0.824 g per year (95% CI: -3.112, 1.464). The risk of low birth weight decreased with the increase of maternal age until 36 years old (OR = 0.917, 95%CI: 0.903, 0.932 when maternal age was younger than 27 years old; OR = 0.965, 95%CI: 0.955, 0.976 when maternal age ranged from 27 to 36 years old), then increased when maternal age was older than 36 years old (OR = 1.133, 95%CI: 1.026, 1.250). The risk of macrosomia increased with the increase of maternal age (OR = 1.102, 95%CI: 1.075, 1.129 when maternal age was younger than 24 years old; OR = 1.065, 95%CI: 1.060, 1.071 when maternal age ranged from 24 to 33 years old; OR = 1.029, 95%CI: 1.012, 1.046 when maternal age was older than 33 years old). Conclusions For women of childbearing age (20–40 years old), the threshold of maternal age on low birth weight was 36 years old, and the risk of macrosomia increased with the increase of maternal age.


2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Ondine von Ehrenstein ◽  
Anthony Wang ◽  
Jokay Ghosh ◽  
Michelle Wilhelm ◽  
Christina Lombardi ◽  
...  

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