The Effect of Long-term Supplementation With Branched-chain Amino Acid Granules in Patients With Hepatitis C Virus-related Hepatocellular Carcinoma After Radiofrequency Thermal Ablation

2013 ◽  
Vol 47 (4) ◽  
pp. 359-366 ◽  
Author(s):  
Hiroki Nishikawa ◽  
Yukio Osaki ◽  
Eriko Iguchi ◽  
Yorimitsu Koshikawa ◽  
Soichiro Ako ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Amino Acid ◽  
Thermal Ablation ◽  
Radiofrequency Thermal Ablation ◽  
Branched Chain Amino Acid ◽  
Branched Chain

Inhibitory effect of branched-chain amino acid granules on progression of compensated liver cirrhosis due to hepatitis C virus

2008 ◽  
Vol 43 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Masahiro Kobayashi ◽  
Kenji Ikeda ◽  
Yasuji Arase ◽  
Yoshiyuki Suzuki ◽  
Fumitaka Suzuki ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Amino Acid ◽  
Inhibitory Effect ◽  
Branched Chain Amino Acid ◽  
Branched Chain

Oral Branched-Chain Amino Acid Granules Reduce the Incidence of Hepatocellular Carcinoma and Improve Event-Free Survival in Patients with Liver Cirrhosis

2011 ◽  
Vol 29 (3) ◽  
pp. 326-332 ◽  
Author(s):  
Sosuke Hayaishi ◽  
Hobyung Chung ◽  
Masatoshi Kudo ◽  
Emi Ishikawa ◽  
Masahiro Takita ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cirrhosis ◽  
Amino Acid ◽  
Event Free Survival ◽  
Free Survival ◽  
Branched Chain Amino Acid ◽  
Branched Chain

scholarly journals Long-Term Evolution of the Hypervariable Region of Hepatitis C Virus in a Common-Source-Infected Cohort

1998 ◽  
Vol 72 (6) ◽  
pp. 4893-4905 ◽  
Author(s):  
Jane McAllister ◽  
Carmela Casino ◽  
Fiona Davidson ◽  
Joan Power ◽  
Emer Lawlor ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Amino Acid ◽  
Hypervariable Region ◽  
Long Term Evolution ◽  
Common Source ◽  
Single Individual ◽  
Term Evolution ◽  
Flanking Regions

ABSTRACT The long-term evolution of the hepatitis C virus hypervariable region (HVR) and flanking regions of the E1 and E2 envelope proteins have been studied in a cohort of women infected from a common source of anti-D immunoglobulin. Whereas virus sequences in the infectious source were relatively homogeneous, distinct HVR variants were observed in each anti-D recipient, indicating that this region can evolve in multiple directions from the same point. Where HVR variants with dissimilar sequences were present in a single individual, the frequency of synonymous substitution in the flanking regions suggested that the lineages diverged more than a decade previously. Even where a single major HVR variant was present in an infected individual, this lineage was usually several years old. Multiple lineages can therefore coexist during long periods of chronic infection without replacement. The characteristics of amino acid substitution in the HVR were not consistent with the random accumulation of mutations and imply that amino acid replacement in the HVR was strongly constrained. Another variable region of E2 centered on codon 60 shows similar constraints, while HVR2 was relatively unconstrained. Several of these features are difficult to explain if a neutralizing immune response against the HVR is the only selective force operating on E2. The impact of PCR artifacts such as nucleotide misincorporation and the shuffling of dissimilar templates is discussed.

scholarly journals Long-Term Prognostic Factors after Hepatic Resection for Hepatitis C Virus-Related Hepatocellular Carcinoma, with a Special Reference to Viral Status

Liver Cancer ◽  
2018 ◽  
Vol 7 (3) ◽  
pp. 261-276 ◽  
Author(s):  
Masaki Koda ◽  
Shogo Tanaka ◽  
Shigekazu Takemura ◽  
Hiroji Shinkawa ◽  
Masahiko Kinoshita ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Factors ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatic Resection ◽  
Special Reference
Sign in / Sign up

Export Citation Format

Share Document