Early postoperative complications have long-term impact on quality of life after restorative proctocolectomy

Abstract Objectives The aim of this clinical analysis was to evaluate intraoperative and early postoperative complications as well as late findings and the overall patient satisfaction following orthognathic surgery. Materials and Methods In a retrospective, cross-sectional study, 119 patients after orthognathic surgery were included. Surgical approaches were single bilateral sagittal split osteotomy (BSSO (n = 52)), single LeFort-I osteotomy (n = 5) and bimaxillary osteotomy (LeFort-I + BSSO (n = 62)). Intraoperative and early (0–4 weeks postoperative) complications were investigated retrospectively (n = 119), whereas late findings and quality of life were assessed via clinical follow-up and survey (mean: 59 months postoperative) on 48 patients. Results Bad split (n = 4/114) was the most common intraoperative complication followed by one case of severe bleeding. Regarding early postoperative complications, temporary damage of the inferior alveolar nerve after BSSO was most common (n = 33/114), followed by facial nerve dysfunction (n = 3), failed osteosynthesis (n = 2) and one case of postoperative dyspnoea. Permanent hypaesthesia of the lower lip was the most prevalent (n = 28/45(BSSO and LeFort-I + BSSO)) late finding with varying extent, followed by temporomandibular dysfunction (TMD) (n = 25/48). Skeletal relapse mostly occurred after class II treatment, followed by class III, posterior crossbite and open bite. Overall, the surgery improved the patients’ self-perception (85.4%), with 60.4% of patients opting for surgery again. Conclusions Long-term complications after orthognathic surgery occurred more frequently than commonly described in the literature, and analyses of the quality of life show the need for more comprehensive preoperative patient education. Clinical relevance Hypaesthesia of the lower lip presented less as complication but rather as side effect following BSSO. As orthognathic surgery is mostly elective, preoperative patient education is of pivotal importance and should include proactive risk stratification.

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Long-term Impact of Adenotonsillectomy on the Quality of Life of Children with Sleep-disordered breathing

International Archives of Otorhinolaryngology ◽

10.1055/s-0040-1709195 ◽

2020 ◽

Author(s):

Juliana Alves Sousa Caixeta ◽

Jessica Caixeta Silva Sampaio ◽

Vanessa Vaz Costa ◽

Isadora Milhomem Bruno da Silveira ◽

Carolina Ribeiro Fernandes de Oliveira ◽

...

Keyword(s):

Quality Of Life ◽

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Sleep Disordered Breathing ◽

Long Term Effects ◽

Obstructive Sleep ◽

Long Term Impact ◽

Disordered Breathing

Abstract Introduction Adenotonsillectomy is the first-line treatment for obstructive sleep apnea secondary to adenotonsillar hypertrophy in children. The physical benefits of this surgery are well known as well as its impact on the quality of life (QoL), mainly according to short-term evaluations. However, the long-term effects of this surgery are still unclear. Objective To evaluate the long-term impact of adenotonsillectomy on the QoL of children with sleep-disordered breathing (SDB). Method This was a prospective non-controlled study. Children between 3 and 13 years of age with symptoms of SDB for whom adenotonsillectomy had been indicated were included. Children with comorbities were excluded. Quality of life was evaluated using the obstructive sleep apnea questionnaire (OSA-18), which was completed prior to, 10 days, 6 months, 12 months and, at least, 18 months after the procedure. For statistical analysis, p-values lower than 0.05 were defined as statistically significant. Results A total of 31 patients were enrolled in the study. The average age was 5.2 years, and 16 patients were male. The OSA-18 scores improved after the procedure in all domains, and this result was maintained until the last evaluation, done 22 ± 3 months after the procedure. Improvement in each domain was not superior to achieved in other domains. No correlation was found between tonsil or adenoid size and OSA-18 scores. Conclusion This is the largest prospective study that evaluated the long-term effects of the surgery on the QoL of children with SDB using the OSA-18. Our results show adenotonsillectomy has a positive impact in children's QoL.

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Predictors of Quality of Life in Long-Term Follow-up after Restorative Proctocolectomy with Ileal Pouch Anal Anastomosis (IPAA)

Journal of the American College of Surgeons ◽

10.1016/j.jamcollsurg.2017.07.082 ◽

2017 ◽

Vol 225 (4) ◽

pp. S44

Author(s):

Olga Lavryk ◽

Tracy L. Hull ◽

Jean H. Ashburn ◽

Luca Stocchi ◽

Emre Gorgun ◽

...

Keyword(s):

Quality Of Life ◽

Restorative Proctocolectomy ◽

Ileal Pouch ◽

Ileal Pouch Anal Anastomosis ◽

Anal Anastomosis ◽

Long Term Follow Up

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Prophylactic Total Gastrectomy: a Prospective Cohort Study of Long-Term Impact on Quality of Life

Journal of Gastrointestinal Surgery ◽

10.1007/s11605-016-3287-8 ◽

2016 ◽

Vol 20 (12) ◽

pp. 1950-1958 ◽

Cited By ~ 11

Author(s):

Jennifer Muir ◽

Melyssa Aronson ◽

Mary-Jane Esplen ◽

Aaron Pollett ◽

Carol J. Swallow

Keyword(s):

Quality Of Life ◽

Cohort Study ◽

Total Gastrectomy ◽

Prospective Cohort Study ◽

Prospective Cohort ◽

Long Term Impact ◽

Prophylactic Total Gastrectomy

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Antibiotic treatment of exacerbations of COPD in general practice: long-term impact on healthrelated quality of life

International Journal of Chronic Obstructive Pulmonary Disease ◽

10.2147/copd.s8732 ◽

2010 ◽

pp. 11 ◽

Cited By ~ 3

Author(s):

Miravitlles

Keyword(s):

Quality Of Life ◽

General Practice ◽

Antibiotic Treatment ◽

Long Term Impact ◽

Healthrelated Quality Of Life

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Long-Term Impact of Sleep-Disordered Breathing on Quality of Life in Children With Obesity

Journal of Clinical Sleep Medicine ◽

10.5664/jcsm.6998 ◽

2018 ◽

Vol 14 (03) ◽

pp. 451-458 ◽

Cited By ~ 3

Author(s):

Sherri L. Katz ◽

Joanna E. MacLean ◽

Nicholas Barrowman ◽

Lynda Hoey ◽

Linda Horwood ◽

...

Keyword(s):

Quality Of Life ◽

Sleep Disordered Breathing ◽

Long Term Impact ◽

Disordered Breathing

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The Long Term Impact of Cytomegalovirus (CMV) Viremia on Quality of Life in Allogeneic Haematopoietic Cell Transplant Recipients (HCT)

Biology of Blood and Marrow Transplantation ◽

10.1016/j.bbmt.2019.12.189 ◽

2020 ◽

Vol 26 (3) ◽

pp. S359-S360

Author(s):

Michelle Yong ◽

Sonia Raj ◽

Zhi Han Yeoh ◽

Monica Anne Slavin ◽

Yvonne Panek-Hudson ◽

...

Keyword(s):

Quality Of Life ◽

Cell Transplant ◽

Transplant Recipients ◽

Haematopoietic Cell ◽

Long Term Impact

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275 POSTOPERATIVE COMPLICATIONS DO NOT AFFECT QUALITY OF LIFE AFTER ESOPHAGECTOMY

Diseases of the Esophagus ◽

10.1093/dote/doaa087.59 ◽

2020 ◽

Vol 33 (Supplement_1) ◽

Author(s):

E Jezerskyte ◽

H Laarhoven ◽

M Sprangers ◽

W Eshuis ◽

M Hulshof ◽

...

Keyword(s):

Quality Of Life ◽

Postoperative Complications ◽

Term Survival ◽

Radio Therapy ◽

Significant Difference ◽

Patient Reported ◽

Short And Long Term ◽

Over Time

Abstract Despite the attempts to reduce postoperative complication incidence after esophageal cancer surgery, up to 60% of patients endure postoperative complications. These patients often have a reduced health related quality of life (HR-QoL) and it may also have a negative effect on long-term survival. The aim of this study is to investigate the difference in short- and long-term HR-QoL in patients with and without a complicated postoperative course. Methods A retrospective comparative cohort study was performed with data from the Dutch Cancer Registry (IKNL) and QoL questionnaires from POCOP, a longitudinal patient reported outcomes study. All patients with esophageal and gastroesophageal junction (GEJ) cancer after an esophagectomy with or without neoadjuvant chemo(radio) therapy in the period of 2015–2018 were included. Exclusion criteria were palliative surgery, patients with a recurrence, reconstruction with a colonic or jejunal interposition, no reconstruction and emergency surgery. HR-QoL was investigated at baseline and at 3, 6, 9, 12, 18 and 24 months postoperatively between patients with and without complications following an esophagectomy. Results A total of 486 patients were included: 270 with and 216 without postoperative complications. The majority of patients were male (79.8%) with a median age of 66 years (IQR 60–70.25). Significantly more patients had comorbidities in the group with postoperative complications (69.6% vs 57.3%, p = 0.001). A significant difference in HR-QoL over time was found between the two groups in “choked when swallowing” score (p = 0.028). Patients that endured postoperative complications reported more problems with choking when swallowing at 9 months follow-up (mean score 12.9 vs 8.4, p = 0.047). This difference was not clinically relevant with a mean score difference of 4.6 points. Conclusion Postoperative complications do not significantly influence the short- and long-term HR-QoL in patients following an esophagectomy. Only one HR-QoL domain showed difference over time, however, this was not clinically relevant.

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P12 LONG-TERM QUALITY OF LIFE AFTER TOTAL GASTRECTOMY VERSUS IVOR LEWIS ESOPHAGECTOMY

Diseases of the Esophagus ◽

10.1093/dote/doz092.12 ◽

2019 ◽

Vol 32 (Supplement_2) ◽

Author(s):

E Jezerskyte ◽

L M Saadeh ◽

E R C Hagens ◽

M A G Sprangers ◽

L Noteboom ◽

...

Keyword(s):

Quality Of Life ◽

Postoperative Complications ◽

Total Gastrectomy ◽

Nausea And Vomiting ◽

Ivor Lewis ◽

Ivor Lewis Esophagectomy ◽

Significant Difference

Abstract Aim The aim of this study was to investigate the difference in long-term health-related quality of life in patients undergoing total gastrectomy versus Ivor Lewis esophagectomy in a tertiary referral center. Background & Methods Surgical treatment for gastroesophageal junction (GEJ) cancers is challenging. Both a total gastrectomy and an esophagectomy can be performed. Which of the two should be preferred is unknown given the scarce evidence regarding effects on surgical morbidity, pathology, long-term survival and health-related quality of life (HR-QoL). From 2014 to 2018, patients with a follow-up of > 1 year after either a total gastrectomy or an Ivor Lewis esophagectomy for GEJ or cardia carcinoma completed the EORTC QLQ-C30 and EORTC QLQ-OG25 questionnaires. Problems with eating, reflux and nausea and vomiting were chosen as the primary HR-QoL endpoints. The secondary endpoints were the remaining HR-QoL domains, postoperative complications and pathology results. Multivariable linear regression was applied taking confounders age, gender, ASA classification and neoadjuvant therapy into account. Results 30 patients after gastrectomy and 71 after Ivor Lewis esophagectomy with a mean age of 63 years were included. Median follow-up was two years (range 12-84 months). Patients after total gastrectomy reported significantly less choking when swallowing and coughing (β=-5.952, 95% CI -9.437 – -2.466; β=-13.084, 95% CI -18.525 – -7.643). Problems with eating, reflux and nausea and vomiting were not significantly different between the two groups. No significant difference was found in postoperative complications or Clavien-Dindo grade. Significantly more lymph nodes were resected in esophagectomy group (p=0.008). No difference in number of positive lymph nodes or R0 resection was found. Conclusion After a follow-up of > 1 year choking when swallowing and coughing were less common after total gastrectomy. No significant difference was found in problems with eating, reflux or nausea and vomiting nor in postoperative complications or radicality of surgery. Based on this study no general preference can be given to either of the procedures for GEJ cancer. Patients may be informed about the HR-QoL domains that are likely to be affected by the different surgical procedures, which in turn may support shared decision making when a choice between the two treatment options is possible.

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