Fractionated Neem Leaf Extract is Safe and Increases CD4+ Cell Levels in HIV/AIDS Patients

2007 ◽  
Vol 14 (4) ◽  
pp. 369-374 ◽  
Author(s):  
A U Mbah ◽  
I J Udeinya ◽  
E N Shu ◽  
C P Chijioke ◽  
T Nubila ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Aids Patients ◽  
Cd4 Cell ◽  
Neem Leaf Extract ◽  
Hiv Aids

scholarly journals Factors associated with prognostic or treatment outcomes in HIV/AIDS patients with and without hypertension in Eswatini

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sabelo Bonginkosi Dlamini ◽  
Hans-Uwe Dahms ◽  
Ming-Tsang Wu
Keyword(s):  
Viral Load ◽  
P Value ◽  
Aids Patients ◽  
Large Hospital ◽  
Hypertensive Patients ◽  
Factors Associated ◽  
Cell Counts ◽  
Cd4 Cell Counts ◽  
Cd4 Cell ◽  
Hiv Aids

AbstractNon-communicable diseases are increasing faster in HIV/AIDS patients than in the general population. We studied the association between hypertension and other possible confounding factors on viral load and CD4-cell counts in hypertensive and non-hypertensive HIV/AIDS patients receiving antiretroviral therapy (ART) at a large hospital in Eswatini over a 4-year period. We performed a retrospective longitudinal review of the medical records of 560 ART patients divided into non-hypertension and hypertension groups (n = 325 and n = 235) from July 27 to September 8, 2018. Generalized Estimated Equation was used to analyze the longitudinal data. Hypertensive patients were more likely to have improved CD4-cell counts than non-hypertensive patients (OR = 1.83, [1.37–2.44]). ART patients with hypertension were more likely to have detectable viral loads, though not significant (OR = 1.37 [0.77–2.43]). In non-hypertensive patients, second line ART was significantly associated with viral load (OR = 8.61 [2.93–25.34]) and adverse side effects (OR = 3.50 [1.06–11.54]), while isoniazid preventive therapy was significantly associated with CD4-cell counts (OR = 1.68 [1.16–2.45]). In hypertensive patients, factors associated with viral load were WHO HIV stage (OR = 2.84 [1.03–7.85]) and adherence (OR = 8.08 [1.33–49.04]). In both groups, CD4-cell counts significantly and steadily increased over time (p-value < 0.001). Results show a significant association between hypertension and CD4 cell counts but not viral load. In ART patients with and without hypertension, the factors associated with prognostic markers were different. More attention may need to be paid to ART patients with well controlled HIV status to monitoring and controlling of hypertension status.

Effects of CD4 cell count and antiretroviral therapy on mucocutaneous manifestations among HIV/AIDS patients in Yunnan, China

2019 ◽  
Vol 59 (3) ◽  
pp. 308-313 ◽  
Author(s):  
Yu‐Ye Li ◽  
Shi‐Han Yang ◽  
Rui‐Rui Wang ◽  
Jun‐Ting Tang ◽  
Hong‐Mei Wang ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Cell Count ◽  
Aids Patients ◽  
Cd4 Cell Count ◽  
Cd4 Cell ◽  
Hiv Aids

scholarly journals Seroprevalence Toxoplasma Infection among HIV/AIDS Patients in Kathmandu, Nepal

2021 ◽  
Vol 23 (1) ◽  
pp. 72-75
Author(s):  
Swatantra Bhandari ◽  
S KC ◽  
L Devkota ◽  
S Khadka ◽  
G Rai ◽  
...  
Keyword(s):  
Toxoplasmic Encephalitis ◽  
Serum Samples ◽  
Toxoplasma Infection ◽  
Aids Patients ◽  
Cd4 Cell Count ◽  
Cell Counts ◽  
National Public Health ◽  
Threatening Condition ◽  
Cd4 Cell ◽  
Hiv Aids

Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii affecting about one third of the world’s population. It can be asymptomatic to fatal toxoplasmic encephalitis depending on the immune status of infected individuals. Among HIV/AIDS patients, it usually manifest as life-threatening condition. We, therefore, studied the seroprevalence of T. gondii infection among HIV/AIDS patients in Nepal and this report constitutes the first report from Nepal. A total of 45 HIV/AIDS patients were included in this study. The serum samples collected and stored at -20°C were tested for Toxoplasma IgG and IgM antibodies at National Public Health Laboratory, Teku, Kathmandu using Snibe Maglumi 1000 Fully Automated Immunoassay Analyzer and the results were expressed in AU/ml. The blood put into the EDTA tube was used for CD4 count using BD FACS Calibur Flow Cytometer. In this study, 33.3% (15/45) HIV infected patients were seropositive for anti-T. gondii IgG. However, none of them were positive to anti- T. gondii IgM. Most of the patients (36 out of 45 patients) had <200/mm3 CD4 cell count. However, out of them 36.1% (13/36) were seropositive to anti-T. gondii IgG whereas 22.2% (2/9) patients with ≥200 CD4 cell counts had Toxoplasma antibodies (p >0.05).

scholarly journals Toxoplasmosis Among HIV Patients and Healthy Volunteers in Port Harcourt, Rivers State, Nigeria

2020 ◽  
Vol 7 (2) ◽  
Author(s):  
Evelyn O Onosakponome ◽  
Austin E Abah ◽  
Michael Wogu
Keyword(s):  
Risk Factors ◽  
Healthy Volunteers ◽  
Hiv Positive ◽  
Hiv Patients ◽  
Aids Patients ◽  
Cell Counts ◽  
Cd4 Cell Counts ◽  
Port Harcourt ◽  
Cd4 Cell ◽  
Hiv Aids

Background: Toxoplasmosis is a serious infection, especially among the immune-compromised people such as HIV/AIDS patients. Objectives: This study assessed the seroprevalence and associated risk factors of toxoplasmosis among HIV patients and healthy volunteers or immuno-competent persons (IP) in Port Harcourt. Methods: A total of 400 (200 per group) randomly-selected sera were tested for IgG and IgM T. gondii antibodies using ELISA technique. CD4 cell counts were also determined. Demographic and risk factors were determined using a well-structured questionnaire. Results: Overall seroprevalence for HIV and IP using IgG and IgM toxoplasma antibodies was 36.0%, 21.5%, and 1.5%, 7.0%, respectively. The age group f 40 years and above had the highest seroprevalence of 25.3% among the HIV positive persons, while the age groups 25 - 29 years had the highest seroprevalence of 20.0% among the IP. Traders’ positive with HIV had the highest seroprevalence of 30.0% and 0.9% for IgG and IgM toxoplasma antibodies, respectively. HIV subjects with a secondary education showed the highest seroprevalence of 20.0%. More HIV positive females were infected with toxoplasmosis 18.5%. In all, 6.7% (P > 0.05) of the seropositive patients had CD4 cell counts of less than 200 cells/µL, indicating no correlation between seroprevalence and CD4 cell counts of HIV/AIDS patients. Risk factors in this study included the history of living with pets, farming and eating improperly-washed fruits and vegetables. Conclusions: Seroprevalence of Toxoplasmosis was high among HIV patients in Port Harcourt. It is suggested that the institutions included the Toxoplasmosis test as one of the routine tests for HIV patients.

scholarly journals The effect of longitudinal body weight and CD4 cell progression for the survival of HIV/AIDS patients

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Gebru Gebremeskel Gebrerufael ◽  
Zeytu Gashaw Asfaw ◽  
Dessie Melese Chekole
Keyword(s):  
Body Weight ◽  
Aids Patients ◽  
Cell Progression ◽  
Cd4 Cell ◽  
Hiv Aids
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