scholarly journals Helping Older Adults Improve Their Medication Experience (HOME) by Addressing Medication Regimen Complexity in Home Healthcare

2018 ◽  
Vol 36 (1) ◽  
pp. E1-E2
Keyword(s):  
Older Adults ◽  
Home Healthcare ◽  
Medication Regimen ◽  
Medication Regimen Complexity ◽  
Regimen Complexity ◽  
Medication Experience

scholarly journals Helping Older Adults Improve Their Medication Experience (HOME) by Addressing Medication Regimen Complexity in Home Healthcare

2018 ◽  
Vol 36 (1) ◽  
pp. 10-19 ◽  
Author(s):  
Orla C. Sheehan ◽  
Hadi Kharrazi ◽  
Kimberly J. Carl ◽  
Bruce Leff ◽  
Jennifer L. Wolff ◽  
...  
Keyword(s):  
Older Adults ◽  
Home Healthcare ◽  
Medication Regimen ◽  
Medication Regimen Complexity ◽  
Regimen Complexity ◽  
Medication Experience

scholarly journals Medication regimen complexity in ambulatory older adults with heart failure

2017 ◽  
Vol Volume 12 ◽  
pp. 679-686 ◽  
Author(s):  
Michael Cobretti ◽  
Robert Page II ◽  
Sunny Linnebur ◽  
Kimberly Deininger ◽  
Amrut Ambardekar ◽  
...  
Keyword(s):  
Heart Failure ◽  
Older Adults ◽  
Medication Regimen ◽  
Medication Regimen Complexity ◽  
Regimen Complexity

scholarly journals Medication-Related Factors and Hospital Readmission in Older Adults with Chronic Kidney Disease

2019 ◽  
Vol 8 (3) ◽  
pp. 395 ◽  
Author(s):  
Wubshet H. Tesfaye ◽  
Gregory M. Peterson ◽  
Ronald L. Castelino ◽  
Charlotte McKercher ◽  
Matthew Jose ◽  
...  
Keyword(s):  
Older Adults ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Hospital Readmission ◽  
Hospital Readmissions ◽  
Medication Regimen ◽  
Related Factors ◽  
Medication Regimen Complexity ◽  
Regimen Complexity ◽  
Medication Appropriateness

This study aimed to examine the association between medication-related factors and risk of hospital readmission in older patients with chronic kidney disease (CKD). A retrospective analysis was conducted targeting older CKD (n = 204) patients admitted to an Australian hospital. Medication appropriateness (Medication Appropriateness Index; MAI), medication regimen complexity (number of medications and Medication Regimen Complexity Index; MRCI) and use of selected medication classes were exposure variables. Outcomes were occurrence of readmission within 30 and 90 days, and time to readmission within 90 days. Logistic and Cox hazards regression were used to identify factors associated with readmission. Overall, 50 patients (24%) were readmitted within 30 days, while 81 (40%) were readmitted within 90 days. Mean time to readmission within 90 days was 66 (SD 34) days. Medication appropriateness and regimen complexity were not independently associated with 30- or 90-day hospital readmissions in older adults with CKD, whereas use of renin‒angiotensin blockers was associated with reduced occurrence of 30-day (adjusted OR 0.39; 95% CI 0.19–0.79) and 90-day readmissions (adjusted OR 0.45; 95% CI 0.24–0.84) and longer time to readmission within 90 days (adjusted HR 0.52; 95% CI 0.33–0.83). This finding highlights the importance of considering the potential benefits of individual medications during medication review in older CKD patients.

Validation and standardization of the Brazilian version of the Medication Regimen Complexity Index for older adults in primary care

2018 ◽  
Vol 18 (6) ◽  
pp. 853-859 ◽  
Author(s):  
Laís LN Pantuzza ◽  
Maria das Graças B Ceccato ◽  
Micheline R Silveira ◽  
Isabela VL Pinto ◽  
Adriano Max M Reis
Keyword(s):  
Older Adults ◽  
Primary Care ◽  
Medication Regimen ◽  
Medication Regimen Complexity ◽  
Complexity Index ◽  
Brazilian Version ◽  
Regimen Complexity

Factors associated with high medication regimen complexity in primary care older adults in Brazil

2019 ◽  
Vol 11 (2) ◽  
pp. 279-287 ◽  
Author(s):  
Laís Lessa Neiva Pantuzza ◽  
Maria das Graças Braga Ceccato ◽  
Edna Afonso Reis ◽  
Micheline Rosa Silveira ◽  
Celline Cardoso Almeida-Brasil ◽  
...  
Keyword(s):  
Older Adults ◽  
Primary Care ◽  
Medication Regimen ◽  
Factors Associated ◽  
Medication Regimen Complexity ◽  
Regimen Complexity

Patient-level Medication Regimen Complexity in Older Adults With Depression

2014 ◽  
Vol 36 (11) ◽  
pp. 1538-1546.e1 ◽  
Author(s):  
Sunny A. Linnebur ◽  
Joseph P. Vande Griend ◽  
Kelli R. Metz ◽  
Patrick W. Hosokawa ◽  
Jan D. Hirsch ◽  
...  
Keyword(s):  
Older Adults ◽  
Medication Regimen ◽  
Patient Level ◽  
Medication Regimen Complexity ◽  
Regimen Complexity

scholarly journals A Cross-Sectional Assessment of Urinary Tract Infections Among Geriatric Patients: Prevalence, Medication Regimen Complexity, and Factors Associated With Treatment Outcomes

2021 ◽  
Vol 9 ◽  
Author(s):  
Ali Akhtar ◽  
Mohamed Azmi Ahmad Hassali ◽  
Hadzliana Zainal ◽  
Irfhan Ali ◽  
Amer Hayat Khan
Keyword(s):  
Older Adults ◽  
Urinary Tract ◽  
Treatment Outcomes ◽  
Medication Regimen ◽  
Cross Sectional ◽  
Factors Associated ◽  
Medication Regimen Complexity ◽  
Regimen Complexity ◽  
Study Population ◽  
Tract Infections

Background: Urinary tract infections (UTIs) are the second most prevalent infection among the elderly population. Hence, the current study aimed to evaluate the prevalence of UTIs among older adults, medication regimen complexity, and the factors associated with the treatment outcomes of elderly patients infected with UTIs.Methods: A retrospective cross-sectional study was conducted at the Department of Urology, Hospital Pulau Pinang, Malaysia. The patients ≥65 years of age were included in the present study with a confirmed diagnosis of UTIs from 2014 to 2018 (5 years).Results: A total of 460 patients met the inclusion criteria and were included in the present study. Cystitis (37.6%) was the most prevalent UTI among the study population followed by asymptomatic bacteriuria (ASB) (31.9%), pyelonephritis (13.9%), urosepsis (10.2%), and prostatitis (6.4%). Unasyn (ampicillin and sulbactam) was used to treat the UTIs followed by Bactrim (trimethoprim/sulfamethoxazole), and ciprofloxacin. The factors associated with the treatment outcomes of UTIs were gender (odd ratio [OR] = 1.628; p = 0.018), polypharmacy (OR = 0.647; p = 0.033), and presence of other comorbidities (OR = 2.004; p = 0.002) among the study population.Conclusion: Cystitis is the most common UTI observed in older adults. Gender, the burden of polypharmacy, and the presence of comorbidities are the factors that directly affect the treatment outcomes of UTIs among the study population.

scholarly journals Medication Regimen Complexity and Hospital Readmission in Older Adults With Chronic Kidney Disease

2018 ◽  
Vol 53 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Wubshet H. Tesfaye ◽  
Gregory M. Peterson ◽  
Ronald L. Castelino ◽  
Charlotte McKercher ◽  
Matthew D. Jose ◽  
...  
Keyword(s):  
Older Adults ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Hospital Admissions ◽  
Tertiary Care ◽  
Care Hospital ◽  
Medication Regimen ◽  
Related Factors ◽  
Medication Regimen Complexity ◽  
Regimen Complexity

Background: Chronic kidney disease (CKD) is characterized by high rates of hospital admissions and readmissions. However, there is a scarcity of research into medication-related factors predicting such outcomes in this patient group. Objective: To evaluate the effect of medication regimen complexity at hospital discharge on subsequent readmissions and their timing in older adults with CKD. Methods: This was a 12-month retrospective cohort study of 204 older (⩾65 years) CKD patients in an Australian tertiary care hospital. Medication regimen complexity was quantified using the 65-item medication regimen complexity index (MRCI). The outcomes were the occurrence of readmission in 30 days and time to readmission within 12 months. Logistic regression was used to identify factors predicting 30-day readmission, and a competing risks proportional subdistribution hazard model, accounting for deaths, was used for factors predicting time to readmission. Results: Overall, 50 (24%) patients, predominantly men (72%), were readmitted within 30 days of follow-up. MRCI was not significantly associated with 30-day readmission (odds ratio [OR] = 1.27; 95% CI = 0.94-1.73). The median (interquartile range) time to readmission within 12 months was 145 (31-365) days. On a multivariate analysis, a 10-unit increase in MRCI was associated with a shorter time to readmission within 12 months (subdistribution HR = 1.18; 95% CI = 1.01-1.36). Conclusion and Relevance: Medication regimen complexity was not significantly associated with 30-day readmission; however, it was associated with a significantly shorter time to 12-month readmission in older CKD patients. This finding highlights the importance of medication regimen complexity as a potential target for medical interventions to reduce readmission risks.

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