Differentiated Immunohistochemical Expression of Osteoclastogenic Markers in Radicular Cyst, Odontogenic Keratocyst, and Ameloblastoma

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Diogo L. Capella ◽  
Bubacar Embaló ◽  
Daniella S.C. Vieira ◽  
Rogério O. Gondak ◽  
Elena R.C. Rivero
2018 ◽  
Vol 61 (1) ◽  
pp. 17-21
Author(s):  
Zohreh Jaafari-Ashkavandi ◽  
Ahmad Alipour Tuyeh ◽  
Sepideh Assar

CDC7 is a serine/threonine kinase which has an essential role in initiation of DNA proliferation and S phase. It increases the invasion and proliferation in many pathologic lesions. This study aimed to evaluate the expression of CDC7 in the most common odontogenic cysts. We evaluated 17 dentigerous cysts, 18 odontogenic keratocysts (OKC) and 13 radicular cysts immunohistochemically. The mean expression of CDC7 was analyzed using ANOVA and Post-HOC methods. All specimens revealed CDC7 expression. Higher expression of CDC7 in OKC and radicular cyst was shown in comparison to dentigerous cyst (P < 0.001), while radicular cyst and OKC groups showed no difference in CDC7 expression (P = 0.738). The high expression of CDC7 in OKC suggests that this protein could be related to the higher proliferation rate and invasiveness of OKC. On the other hand, the higher CDC7 expression in radicular cyst may simply be related to inflammation as this cyst is neither aggressive nor invasive.


1995 ◽  
Vol 49 (1) ◽  
pp. 157-165
Author(s):  
Qi Zhao ◽  
Tung Huai Hsu ◽  
Eiko Nakanishi ◽  
Chihiro Iuchi ◽  
Michihiro Takubo ◽  
...  

Author(s):  
Premkumar ◽  
Maya Ramesh ◽  
Mathew Jacob ◽  
B Sekar ◽  
K. Indrapridharshini ◽  
...  

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