scholarly journals Feasibility and efficacy of early lung cancer diagnosis with chest computed tomography in HIV-infected smokers

AIDS ◽  
2016 ◽  
Vol 30 (4) ◽  
pp. 573-582 ◽  
Author(s):  
Alain Makinson ◽  
Sabrina Eymard-Duvernay ◽  
François Raffi ◽  
Sophie Abgrall ◽  
Sébastien Bommart ◽  
...  
Mathematics ◽  
2021 ◽  
Vol 9 (13) ◽  
pp. 1457
Author(s):  
Muazzam Maqsood ◽  
Sadaf Yasmin ◽  
Irfan Mehmood ◽  
Maryam Bukhari ◽  
Mucheol Kim

A typical growth of cells inside tissue is normally known as a nodular entity. Lung nodule segmentation from computed tomography (CT) images becomes crucial for early lung cancer diagnosis. An issue that pertains to the segmentation of lung nodules is homogenous modular variants. The resemblance among nodules as well as among neighboring regions is very challenging to deal with. Here, we propose an end-to-end U-Net-based segmentation framework named DA-Net for efficient lung nodule segmentation. This method extracts rich features by integrating compactly and densely linked rich convolutional blocks merged with Atrous convolutions blocks to broaden the view of filters without dropping loss and coverage data. We first extract the lung’s ROI images from the whole CT scan slices using standard image processing operations and k-means clustering. This reduces the search space of the model to only lungs where the nodules are present instead of the whole CT scan slice. The evaluation of the suggested model was performed through utilizing the LIDC-IDRI dataset. According to the results, we found that DA-Net showed good performance, achieving an 81% Dice score value and 71.6% IOU score.


2021 ◽  
Vol 8 ◽  
Author(s):  
Su-Ju Wei ◽  
Li-Ping Wang ◽  
Jun-Yan Wang ◽  
Jing-Xu Ma ◽  
Feng-Bin Chuan ◽  
...  

Objective: The objective of this research is to explore the diagnostic value of imaging plus tumor markers in the early detection of lung cancer.Methods: Sixty patients with lung cancer treated in our hospital from January 2018 to January 2019 were selected as group A. They were matched with 60 patients with benign lung disease as group B and 60 healthy subjects examined in our hospital as group C. The carcino-embryonic antigen (CEA), CYFRA21-1, and neuron-specific enolase (NSE) were assessed, and the diagnostic value of tumor markers plus imaging in lung cancer diagnosis was explored.Results: The CEA, CYFRA21-1, and NSE in group A were evidently superior to those in groups B and C, and those in group B were superior to those in group C (all P < 0.001). CEA had the highest sensitivity (56.7%), and NSE had the highest specificity (93.3%). The tumor markers plus imaging had the highest sensitivity for different types of lung cancer, and the sensitivity to early lung cancer (90%) was superior to other diagnostic methods (P < 0.05).Conclusion: The tumor markers plus imaging is of great significance in early lung cancer diagnosis and provides a reference for judging the pathological classification.


2021 ◽  
pp. 48-58
Author(s):  
Mafe Roa ◽  
Laura Daza ◽  
Maria Escobar ◽  
Angela Castillo ◽  
Pablo Arbelaez

2020 ◽  
Vol 47 (9) ◽  
pp. 4125-4136
Author(s):  
Noemi Garau ◽  
Chiara Paganelli ◽  
Paul Summers ◽  
Wookjin Choi ◽  
Sadegh Alam ◽  
...  

Author(s):  
S. Vishwa Kiran ◽  
Inderjeet Kaur ◽  
K. Thangaraj ◽  
V. Saveetha ◽  
R. Kingsy Grace ◽  
...  

In recent times, the healthcare industry has been generating a significant amount of data in distinct formats, such as electronic health records (EHR), clinical trials, genetic data, payments, scientific articles, wearables, and care management databases. Data science is useful for analysis (pattern recognition, hypothesis testing, risk valuation) and prediction. The major, primary usage of data science in the healthcare domain is in medical imaging. At the same time, lung cancer diagnosis has become a hot research topic, as automated disease detection poses numerous benefits. Although numerous approaches have existed in the literature for lung cancer diagnosis, the design of a novel model to automatically identify lung cancer is a challenging task. In this view, this paper designs an automated machine learning (ML) with data science-enabled lung cancer diagnosis and classification (MLDS-LCDC) using computed tomography (CT) images. The presented model initially employs Gaussian filtering (GF)-based pre-processing technique on the CT images collected from the lung cancer database. Besides, they are fed into the normalized cuts (Ncuts) technique where the nodule in the pre-processed image can be determined. Moreover, the oriented FAST and rotated BRIEF (ORB) technique is applied as a feature extractor. At last, sunflower optimization-based wavelet neural network (SFO-WNN) model is employed for the classification of lung cancer. In order to examine the diagnostic outcome of the MLDS-LCDC model, a set of experiments were carried out and the results are investigated in terms of different aspects. The resultant values demonstrated the effectiveness of the MLDS-LCDC model over the other state-of-the-art methods with the maximum sensitivity of 97.01%, specificity of 98.64%, and accuracy of 98.11%.


Sign in / Sign up

Export Citation Format

Share Document