Role of Arterial Perfusion in Early Survival of Arterialized Venous Flaps

ASL (Arterial Spin Labeling) – a novel modality of MR angiography – is based on radio-frequency labeling of aqueous protons in the arterial blood; the method is used to monitor blood supply to organs, including the brain. So far there has been little information on the use of ASL in children with focal epilepsy, especially in the pre-surgery period.Aim:to evaluate the perfusion patterns in seizure-free children with drug resistant focal epilepsy (FE) using the ASL mode of MRI.Materials and methods.We studied the ASL data of 54 (23-boys/31 girls) patients with FE treated in the Dpt. of Neurology at the Russian State Children Hospital from 2015 to 2018. The patients’ age varied from 4 months to 17 years. All images were produced with a 3T GE Discovery 750W system.Results. We found several brain perfusion patterns in children with FE; among other factors, those patterns depended on the clinical status of the patient, i. e. the interictal period or the early post- seizure period. The main pattern of the interictal period was characterized by a focal decrease in perfusion located around a structural focus identified on MRI scans. In the early post-seizure period, there was an increase in the arterial perfusion in the area of a structural epileptogenic lesion.Conclusion.ASL-MRI is an effective diagnostic method providing more information on children with FE during their pre-surgery phase. The ASL modality needs further research to rationalize its wider use as a preferred diagnostic tool or as a combination with the more complex PET and SPECT.

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The role of hepatic arterial flow on portal venous and hepatic venous wedged pressure in the isolated perfused CCl4-cirrhotic liver

AJP Gastrointestinal and Liver Physiology ◽

10.1152/ajpgi.00190.2007 ◽

2008 ◽

Vol 295 (1) ◽

pp. G197-G202 ◽

Cited By ~ 17

Author(s):

Alexander Zipprich ◽

Mauricio R. Loureiro-Silva ◽

Irita D'Silva ◽

Roberto J. Groszmann

Keyword(s):

Liver Perfusion ◽

Venous Pressure ◽

Arterial Flow ◽

Hepatic Arterial Flow ◽

Drug Induced ◽

Arterial Perfusion ◽

Elevated Pressures ◽

Flow Pressure ◽

And Control

In cirrhosis, hepatic venous pressure gradient is used to measure portal venous and sinusoidal pressures, as well as drug-induced decreases of elevated pressures. The aim of this study was to investigate the influence of hepatic arterial flow (HAF) changes on portal venous perfusion (PVPP) and wedged hepatic venous pressure (WHVP). Normal and CCl4-cirrhotic rats were subjected to a bivascular liver perfusion with continuous measurements of PVPP, WHVP, and hepatic arterial perfusion pressure. Flow-pressure curves were performed with the use of different flows either through the portal vein (PVF: 20–32 ml/min) or HAF (5–15 ml/min). Increases in HAF lead to significant absolute and relative increases in PVPP ( P = 0.002) and WHVP ( P < 0.001). Absolute changes in HAF correlated to absolute changes in PVPP (cirrhosis: r = 0.64, P < 0.001; control: r = 0.67, P < 0.001) and WHVP (cirrhosis: r = 0.71, P < 0.001; control: r = 0.82, P < 0.001). Changes in PVPP correlated to changes in WHVP due to changes in PVF only in cirrhosis ( r = 0.75, P < 0.001), whereas changes in HAF correlated in both cirrhosis ( r = 0.92, P < 0.001) and control ( r = 0.77, P < 0.001). In conclusion, increases and decreases in HAF lead to respective changes in PVPP and WHVP. This suggests a direct influence of HAF on PVPP and WHVP most likely due to changes in sinusoidal perfusion.

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The complicated role of venous drainage on the survival of arterialized venous flaps

Oncotarget ◽

10.18632/oncotarget.14845 ◽

2017 ◽

Vol 8 (10) ◽

pp. 16414-16420 ◽

Cited By ~ 4

Author(s):

Weidong Weng ◽

Feng Zhang ◽

Bin Zhao ◽

Zhipeng Wu ◽

Weiyang Gao ◽

...

Keyword(s):

Venous Drainage ◽

Venous Flaps

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Studying and Promoting Altruism and Studying and Working to Prevent Genocide: The Guiding Role of Early Survival

The Psychology of Good and Evil ◽

10.1017/cbo9780511615795.004 ◽

2003 ◽

pp. 31-46

Keyword(s):

Early Survival

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Twin Reversed Arterial Perfusion Syndrome: the Role of Ultrasound in Diagnosis and Management

Ultrasound ◽

10.1179/174227109x12500735818188 ◽

2009 ◽

Vol 17 (4) ◽

pp. 227-230 ◽

Cited By ~ 1

Author(s):

Kofi K Yamoah ◽

Maja A Kotlinska ◽

Anne M Coady ◽

Poitr Lesny

Keyword(s):

Arterial Perfusion ◽

Diagnosis And Management ◽

Twin Reversed Arterial Perfusion

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Role of perivenous areolar tissue and recipient bed in the viability of venous flaps in the rabbit ear model

British Journal of Plastic Surgery ◽

10.1016/0007-1226(94)90110-4 ◽

1994 ◽

Vol 47 (1) ◽

pp. 10-14 ◽

Cited By ~ 14

Author(s):

Rick J. Smith ◽

Keizo Fukuta ◽

Michael Wheatley ◽

Ian T. Jackson

Keyword(s):

Areolar Tissue ◽

Venous Flaps ◽

Rabbit Ear

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Transient outward and delayed rectifier currents in canine atrium: properties and role of isolation methods

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.1996.270.6.h2157 ◽

1996 ◽

Vol 270 (6) ◽

pp. H2157-H2168 ◽

Cited By ~ 56

Author(s):

L. Yue ◽

J. Feng ◽

G. R. Li ◽

S. Nattel

Keyword(s):

Cell Voltage ◽

In Vivo Studies ◽

Delayed Rectifier ◽

Human Atrium ◽

Arterial Perfusion ◽

Outward Currents ◽

K Current

Although the dog is the principal species used for in vivo studies of atrial arrhythmias, little is known about currents governing canine atrial repolarization. Cells were isolated from dog atria by exposure to collagenase of tissue in vitro (“chunk cells”) and by arterial perfusion (“perfusion cells”). Whole cell voltage clamp revealed transient outward K+ current (Ito1), Ca(2+)-dependent Cl- current (Ito2), and delayed rectifier K+ current (IK). Ito1 recovered rapidly and showed little frequency dependence. Two components of IK were present as follows: a rapidly activating E-4031-sensitive current with marked inward recitification and a slower-activating E-4031-insensitive component. Ito1 and IK resembled corresponding currents previously described in human atrium. Transient outward currents were similar in chunk and perfusion cells, but IK was seen in 4% of chunk cells vs. 99% of perfusion cells (P < 0.001). Suppression of each identified current retarded canine action potential repolarization. We conclude that Ito1, Ito2, and both components of IK are present in dog atrium, IK is much more sensitive to the isolation method than Ito1 or Ito2, and the properties of two important repolarizing currents (Ito1 and IK) previously described in human atrium are similar to those in dog atrium.

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4D assessment of motoric function in a singleton acephalous fetus: the role of the KANET test

Case Reports in Perinatal Medicine ◽

10.1515/crpm-2017-0022 ◽

2017 ◽

Vol 6 (2) ◽

Author(s):

Akhmad Khalief Emir ◽

Wiku Andonotopo ◽

Muhammad Adrianes Bachnas ◽

Sri Sulistyowati ◽

Milan Stanojevic ◽

...

Keyword(s):

Case Report ◽

Brain Development ◽

Rare Case ◽

Twin Pregnancy ◽

Singleton Pregnancy ◽

Amniotic Band ◽

Arterial Perfusion ◽

4D Ultrasound ◽

And Function

Abstract Acephalous fetus in a singleton pregnancy is an extremely rare case. In twin pregnancy, it could be presumed as one type of twin reverse arterial perfusion sequence (TRAPS). In this particular case report, the situation was different. An acephalous fetus developed in a singleton pregnancy and may have been a complication of an amniotic band in the very early weeks of gestation. Nevertheless proving it is still a constraint. Despite that, motor findings in utero by using four-dimensional (4D) ultrasound were very interesting to study. Movement of the acephalous fetus is challenging thought on fetal behavior theory, as brain development and function play the central role. The Kurjak antenatal neurodevelopmental tests (KANET) was used to measure the fetal behavior of this acephalous fetus. A comparison with post natal movement findings was also done to provide a better understanding.

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