scholarly journals Blood–Brain Barrier Dysfunction After Smoke Inhalation Injury, With and Without Skin Burn

Shock ◽  
2019 ◽  
Vol 51 (5) ◽  
pp. 634-649 ◽  
Author(s):  
Anita C. Randolph ◽  
Satoshi Fukuda ◽  
Koji Ihara ◽  
Perenlei Enkhbaatar ◽  
Maria-Adelaide Micci
Keyword(s):  
Blood Brain Barrier ◽  
Inhalation Injury ◽  
Smoke Inhalation ◽  
Brain Barrier ◽  
Barrier Dysfunction ◽  
Skin Burn ◽  
Smoke Inhalation Injury ◽  
Blood Brain

scholarly journals APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

Nature ◽  
2020 ◽  
Vol 581 (7806) ◽  
pp. 71-76 ◽  
Author(s):  
Axel Montagne ◽  
Daniel A. Nation ◽  
Abhay P. Sagare ◽  
Giuseppe Barisano ◽  
Melanie D. Sweeney ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Barrier Dysfunction ◽  
Blood Brain

Role of thrombin-PAR1-PKCθ/δ axis in brain pericytes in thrombin-induced MMP-9 production and blood–brain barrier dysfunction in vitro

Neuroscience ◽  
2017 ◽  
Vol 350 ◽  
pp. 146-157 ◽  
Author(s):  
Takashi Machida ◽  
Shinya Dohgu ◽  
Fuyuko Takata ◽  
Junichi Matsumoto ◽  
Ikuya Kimura ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Barrier Dysfunction ◽  
Blood Brain ◽  
Brain Pericytes

Blood-brain barrier dysfunction and extension of time window for thrombolysis: a limitation not evaluated

2021 ◽  
Vol 19 ◽  
Author(s):  
Antonio Siniscalchi ◽  
Roman Sztajzel ◽  
Sean Murphy ◽  
Giovambattista De Sarro ◽  
Luca Gallelli
Keyword(s):  
Blood Brain Barrier ◽  
Time Window ◽  
Brain Barrier ◽  
Barrier Dysfunction ◽  
Blood Brain

scholarly journals Relationship Between Amyloid-β Deposition and Blood–Brain Barrier Dysfunction in Alzheimer’s Disease

2021 ◽  
Vol 15 ◽  
Author(s):  
Dong Wang ◽  
Fanglian Chen ◽  
Zhaoli Han ◽  
Zhenyu Yin ◽  
Xintong Ge ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Blood Brain Barrier ◽  
Amyloid Β ◽  
Brain Barrier ◽  
Barrier Dysfunction ◽  
Factors Affecting ◽  
Blood Brain ◽  
Normal Metabolism

Amyloid-β (Aβ) is the predominant pathologic protein in Alzheimer’s disease (AD). The production and deposition of Aβ are important factors affecting AD progression and prognosis. The deposition of neurotoxic Aβ contributes to damage of the blood–brain barrier. However, the BBB is also crucial in maintaining the normal metabolism of Aβ, and dysfunction of the BBB aggravates Aβ deposition. This review characterizes Aβ deposition and BBB damage in AD, summarizes their interactions, and details their respective mechanisms.

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