Prognostic Value of Preoperative Brain Natriuretic Peptide Serum Levels in Liver Transplantation

2016 ◽  
Vol 100 (4) ◽  
pp. 819-824 ◽  
Author(s):  
Amelie Toussaint ◽  
Emmanuel Weiss ◽  
Linda Khoy-Ear ◽  
Sylvie Janny ◽  
Jacqueline Cohen ◽  
...  
2018 ◽  
Vol 14 (64) ◽  
pp. 081
Author(s):  
N. V. Tytarenko ◽  
M. P. Kopytsya ◽  
Yu. V. Rodionova ◽  
L. L. Petenyova ◽  
O. L. Oparin

2003 ◽  
Vol 114 (4) ◽  
pp. 266-270 ◽  
Author(s):  
Ryuji Ueda ◽  
Masatoshi Yokouchi ◽  
Takaomi Suzuki ◽  
Eiichi Otomo ◽  
Takashi Katagiri

2021 ◽  
Vol 10 (21) ◽  
pp. 4868
Author(s):  
Silvia Oghina ◽  
Constant Josse ◽  
Mélanie Bézard ◽  
Mounira Kharoubi ◽  
Marc-Antoine Delbarre ◽  
...  

Background: We assesse the evolution and prognostic value of N-terminal pro-brain natriuretic peptide (NT-proBNP) and high-sensitivity troponin T (cTnT-HS) in transthyretin amyloid cardiomyopathy (ATTR-CA) before and after tafamidis treatment. Methods and Results: 454 ATTR-CA patients without tafamidis (Cohort A) and 248 ATTR-CA with tafamidis (Cohort B) were enrolled. Event-free survival (EFS) events were death, heart transplant, or acute heart failure. In Cohort A, 27% of patients maintained NT-proBNP < 3000 ng/L and 14% cTnT-HS < 50 ng/L at 12 months relative to baseline levels. In Cohort B, the proportions were 49% and 29%, respectively. In Cohort A, among the 333 patients without an increased NT-proBNP > 50% relative to baseline EFS was extended compared to the 121 patients with an increased NT-proBNP > 50% (HR: 0.75 [0.57; 0.98]; p = 0.032). In Cohort A, baseline NT-proBNP > 3000 ng/L and cTnT-HS > 50 ng/L and a relative increase of NT-proBNP > 50% during follow-up were independent prognostic factors of EFS. The slopes of logs NT-proBNP and cTnT-HS increased with time before and stabilized after tafamidis. Conclusion: ATTR-CA patients with increasing NT-proBNP had an increased risk of EFS. Tafamidis stabilize NT-proBNP and cTnT-HS increasing, even if initial NT-proBNP levels were >3000 ng/L. Thus suggesting that all patients, irrespective of baseline NT-proBNP levels, may benefit from tafamidis.


2007 ◽  
Vol 26 (10) ◽  
pp. 986-991 ◽  
Author(s):  
L. Martinez-Dolz ◽  
L. Almenar ◽  
J. Moro ◽  
J. Agüero ◽  
I. Hervas ◽  
...  

2017 ◽  
Vol 42 ◽  
pp. 117-122 ◽  
Author(s):  
Johad Khoury ◽  
Majd Arow ◽  
Adi Elias ◽  
Badira F. Makhoul ◽  
Gidon Berger ◽  
...  

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