Role and clinical implications of atypical antipsychotics in anxiety disorders, obsessive-compulsive disorder, trauma-related, and somatic symptom disorders

2016 ◽  
Vol 31 (5) ◽  
pp. 249-258 ◽  
Author(s):  
Umberto Albert ◽  
Claudia Carmassi ◽  
Fiammetta Cosci ◽  
David De Cori ◽  
Marco Di Nicola ◽  
...  
2014 ◽  
Author(s):  
David MB Christmas ◽  
Ian Crombie ◽  
Sam Eljamel ◽  
Naomi Fineberg ◽  
Bob MacVicar ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Domenico De Berardis ◽  
Nicola Serroni ◽  
Stefano Marini ◽  
Giovanni Martinotti ◽  
Francesca Ferri ◽  
...  

Obsessive-compulsive disorder (OCD) is a chronic condition characterized by obsessions or compulsions that cause distress or interfere with functioning. Selective serotonin reuptake inhibitors are the first-line strategy in the treatment of OCD, but approximately 40% to 60% of patients with OCD fail to respond to them. Several augmentation strategies have been proposed, including the use of atypical antipsychotics and antidepressant combinations. In the present paper we describe the case of a young female patient suffering from severe treatment-resistant OCD who remitted as a result of agomelatine augmentation of escitalopram therapy.


2010 ◽  
Vol 38 (6) ◽  
pp. 759-760
Author(s):  
William Eysenck ◽  
Michael W. Eysenck

In his theory of anxiety disorders, Eysenck (1997) argued that focus on one's own behavior is associated with social phobia, whereas focus on future-oriented threat cognitions is associated with obsessive-compulsive disorder. These foci occur in part because social phobics tend to be introverted and obsessive-compulsives either perceive themselves as having onerous responsibilities or actually do have them (e.g., women with infants). These assumptions have empirical support (Eysenck). We can use the theory to predict cross-cultural differences in anxiety disorders. Social phobia should be more common in introverted cultures. We correlated lifetime incidence of social phobia (data: Wittchen & Fehm, 2001) with extraversion (data: Steel & Ones, 2002) across several countries, obtaining the predicted negative correlation (-0.35). We will expand the database to establish definitively the strength of this association. We will also explore the prediction that people in individualistic countries (emphasizing personal responsibility) have a higher incidence of obsessive-compulsive disorder than those in collectivistic countries, a prediction receiving preliminary support (e.g., Essau, Sakano, Ishikawa, & Sasagawa, 2004).


2012 ◽  
Vol 200 (10) ◽  
pp. 876-884 ◽  
Author(s):  
Agorastos Agorastos ◽  
Tanja Metscher ◽  
Christian G. Huber ◽  
Lena Jelinek ◽  
Francesca Vitzthum ◽  
...  

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