I. Further inquiries as to the structure, development, and function of the liver

1853 ◽  
Vol 143 ◽  
pp. 1-28 ◽  

Since I presented to the Royal Society in 1847 the description which I have given of the structure of the liver, I have become acquainted with the researches of Professor Retzius, and of Dr. Leidy, and have been favoured by M. Natalis Guillot with a view of the preparations on which he grounds the opinions I noticed on that occasion. Professor Retzius describes the hepatic ducts as forming close networks in the sheaths of Glisson’s capsule, perilobular or alveolar networks; from which are given off minute lobular networks interwoven with the portal-hepatic plexuses, and con­stituting with them the substance of the lobules. These plexuses are described as consisting of anastomosing tubes which are formed of a basement or limitary mem­brane, like those of other glands, and in these tubes I presume Professor Retzius considers the hepatic cells to be lodged.

2019 ◽  
Vol 1 (1) ◽  
pp. 1-3
Author(s):  
Venki Ramakrishnan ◽  
Mejd Alsari

Venkatraman ‘Venki’ Ramakrishnan is the President of The Royal Society and Group Leader at the MRC Laboratory of Molecular Biology. In 2009 he shared the Nobel Prize in Chemistry ‘for studies of the structure and function of the ribosome’. In this interview he explains why governments should invest more in basic scientific research rather than simply on applied science and engineering. He also discusses interdisciplinarity, collaborations, and public engagement.


1849 ◽  
Vol 139 ◽  
pp. 109-137 ◽  

In venturing to offer a second communication to the Royal Society respecting the structure of the liver, I feel the rather anxious to do so, that I may have an opportunity of correcting an error and supplying a deficiency which existed in my previous paper. In the following observations I purpose to present some account of the structure of the liver examined in the ascending series of animals, and also to describe the several stages of its evolution in the embryo; in this way I trust I may be able to exhibit the characteristic structural features of the organ as it exists in Man and the higher animals, and also to determine the true place which ought to be assigned to it in a classification of the various glandular organs occurring in the same. I am not aware that any detailed account of the structure of the liver has been recently published, except that by M. Natalis Guillot, which however, so far as I comprehend it, does not seem to be one that can be readily accepted; the idea that the minute biliary ducts and lymphatics originate together in a common net-work, is à priori improbable, and entirely opposed to conclusive evidence (as I think), which will be subsequently adduced. A very interesting paper on the structure and function of the liver has also appeared in the 4th volume of the Guy’s Hospital Reports, from the pen of Dr. Williams; to his labours I shall several times have occasion to refer, but it will be seen that I differ from him in several particulars, especially respecting the importance of the basement or limitary membrane.


Development ◽  
1956 ◽  
Vol 4 (2) ◽  
pp. 97-109
Author(s):  
D. A. T. Dick

Many investigators have demonstrated the decline which takes place in the relative weight of the liver during the development of the mammalian foetus; Carlyle (1945) and Wallace (1945) in the sheep, Jackson (1909) in man, Lowrey (1911) in the pig, Williamson (1948) and Addis & Gray (1950) in the rat, Latimer & Corder (1948) in the dog, and Latimer (1948) in the cat. The present work is an attempt to find the cause underlying this decline. Since the foetal liver contains not only hepatic tissue but also much haemopoietic tissue, it was first necessary to determine whether the decrease in the relative liver-weight represents a real diminution of true hepatic tissue or whether it simply reflects the progressive shift of haemopoiesis from liver to skeleton. In order to test these lternatives a method was devised for determining the total amount of true hepatic tissue, i.e. the total number of hepatic cells, in a given foetal liver, and applied to a series of foetuses covering the developmental period.


2014 ◽  
Vol 58 (10-11-12) ◽  
pp. 819-827 ◽  
Author(s):  
Rafal P. Piprek ◽  
Malgorzata Kloc ◽  
Jacek Z. Kubiak

2012 ◽  
Vol 57 (11) ◽  
pp. 2901-2909 ◽  
Author(s):  
Xing Gu ◽  
Xin Ji ◽  
Le-Hua Shi ◽  
Chang-Hong Yi ◽  
Yun-Peng Zhao ◽  
...  

2019 ◽  
pp. 391-422 ◽  
Author(s):  
Eldon E. Ball ◽  
Brian P. Oldfield ◽  
Karin Michel Rudolph

Sign in / Sign up

Export Citation Format

Share Document