scholarly journals The Role of DNA Synthesis in Virus Replication and the Morphological Transformation of Normal Mouse Embryo Cells by MSV (MOLONEY)

1970 ◽  
Vol 7 (3) ◽  
pp. 249-256 ◽  
Author(s):  
R. Bather ◽  
A. Leonard
Keyword(s):  
Dna Synthesis ◽  
Virus Replication ◽  
Mouse Embryo ◽  
Normal Mouse ◽  
Morphological Transformation ◽  
Embryo Cells

The IGF-I Receptor in Mitogenesis and Transformation of Mouse Embryo Cells: Role of Receptor Number

1997 ◽  
Vol 230 (2) ◽  
pp. 284-292 ◽  
Author(s):  
Michele Rubini ◽  
Atsushi Hongo ◽  
Consuelo D'Ambrosio ◽  
Renato Baserga
Keyword(s):  
Mouse Embryo ◽  
Igf I ◽  
Embryo Cells ◽  
Receptor Number

scholarly journals Characterization of a photoproduct of 7,12-dimethylbenz[a]anthracene and its effects on chick-embryo cells in culture

1977 ◽  
Vol 164 (3) ◽  
pp. 481-486 ◽  
Author(s):  
D Warshawsky ◽  
E Kerns ◽  
M J Bissell ◽  
M Calvin
Keyword(s):  
Chick Embryo ◽  
Dna Synthesis ◽  
Oxidation Product ◽  
Biological Effects ◽  
Cell Number ◽  
Resonance Spectroscopy ◽  
Morphological Transformation ◽  
Morphological Alterations ◽  
Photo Oxidation ◽  
Embryo Cells

A common impurity of 7,12-dimethylbenz[alpha]anthracene was more effective than 7,12-dimethylbenz[alpha]anthracene in inducing morphological alterations, and in causing an increase in glucose uptake, DNA synthesis and cell number in chick-embryo fibroblasts. Gradual morphological transformation follows the increase in DNA synthesis after 2 days when either primary or secondary cultures are treated with 3 microgram of the compound/ml. The compound, isolated from 7,12-dimethylbenz[alpha]anthracene by alumina column chromatography, was characterized by t.l.c., mass spectroscopy, carbon-hydrogen analysis, u.v. and nuclear-magnetic-resonance spectroscopy and thermal decomposition. It was the photo-oxidation product of 7,12-dimethylbenz[alpha]anthracene, 7,12-epidioxy-7,12-dimethylbenz[alpha]anthracene. It is suggested that some of the biological effects observed after treatment of cultures with 7,12-dimethylbenz[alpha]anthracene may be due in part to the presence of the photo-oxidation product.

?-Amanitin and 5-fluorouridine inhibition of serumstimulated DNA synthesis in quiescent AKR-2B mouse embryo cells

1979 ◽  
Vol 100 (2) ◽  
pp. 199-213 ◽  
Author(s):  
David J. Wells ◽  
Linda S. Stoddard ◽  
Michael J. Getz ◽  
Harold L. Moses
Keyword(s):  
Dna Synthesis ◽  
Mouse Embryo ◽  
Embryo Cells
Sign in / Sign up

Export Citation Format

Share Document