scholarly journals The Effects of Low-Level Laser Therapy, 670 nm, on Epiphyseal Growth in Rats

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Adriana Regina de Andrade ◽  
Anamaria Meireles ◽  
Elisangela Lourdes Artifon ◽  
Rose Meire Costa Brancalhão ◽  
José Roberto Leonel Ferreira ◽  
...  

The longitudinal growth of long bones is attributed to epiphyseal growth. However, the effects of low-level laser therapy (LLLT) in such structures has still not been studied extensively in the literature. Therefore, the aim of this study was to evaluate the use of LLLT, 670 nm, at three different doses on the epiphyseal growth of the right tibia of rats. Twenty-one Wistar rats, aged four weeks, were subjected to the application of LLLT, with dosage according to the group (G4: were submitted to the application of 4 J/cm2; G8: were submitted to the application of 8 J/cm2; G16: were submitted to the application of 16 J/cm2). After completion of protocol they were kept until they were 14 weeks of age and then submitted to a radiological examination (evaluation of limb length) and euthanised. The histological analysis of the growth plates (total thickness and hypertrophic and proliferative zones) was then performed. Comparisons were made with the untreated left tibia. No differences were observed in any of the reviews (radiological and histological), when comparing the right sides (treated) to the left (untreated). It was concluded that the treatment with LLLT within the parameters used caused changes neither in areas of the epiphyseal cartilage nor in the final length of limbs.

2010 ◽  
Vol 45 (4) ◽  
pp. 444-448
Author(s):  
Mauricio José Falcai ◽  
Vanessa Vilela Monte-Raso ◽  
Rodrigo Okubo ◽  
Ariane Zamarioli ◽  
Leonardo César Carvalho ◽  
...  

2017 ◽  
Vol 21 (6) ◽  
pp. 425-433 ◽  
Author(s):  
Thiago Alves Garcia ◽  
Regina Celi Trindade Camargo ◽  
Tatiana Emy Koike ◽  
Guilherme Akio Tamura Ozaki ◽  
Robson Chacon Castoldi ◽  
...  

2011 ◽  
Vol 69 (2b) ◽  
pp. 356-359 ◽  
Author(s):  
G R F Bertolini ◽  
E L Artifon ◽  
T S Silva ◽  
D M Cunha ◽  
P R Vigo

Chronic pain, resulting from nerve compression, is a common clinical presentation. One means of conservative treatment is low-level laser therapy, although controversial. The aim of this study was to evaluate the effects of two doses of low-level laser, at 830 nm, on pain reduction in animals subjected to sciatica. Eighteen rats were used, divided into three groups: GS (n=6), sciatica and simulated treatment; G4J (n=6), sciatica and treatment with 4 J/cm²; and G8J (n=6), sciatica and irradiation with 8 J/cm². The right sciatic nerve was exposed and compressed using catgut thread. Five days of treatment were started on the third postoperative day. Pain was assessed by means of the paw elevation time during gait: before sciatica, before and after the first and second therapies, and the end of the fifth therapy. Low-level laser was effective in reducing the painful condition.


2012 ◽  
Vol 27 (2) ◽  
pp. 117-122 ◽  
Author(s):  
Sidney Piesco de Oliveira ◽  
Sheila Canevese Rahal ◽  
Elenize Jamas Pereira ◽  
Paulo Ricardo de Oliveira Bersano ◽  
Fabio de Almeida Vieira ◽  
...  

PURPOSE: To determine the influence of low-level laser therapy on femoral growth plate in rats. METHODS: Thirty male Wistar rats aged 40 days were divided into two groups, G1 and G2. In G1 the area of the distal growth plate of the right femur was irradiated at one point using GaAlAs laser 830 nm wavelength, output power of 40 mW, at an energy density of 10 J/cm². The irradiation was performed daily for a maximum of 21 days. The same procedure was done in G2, but the probe was turned off. Five animals in each group were euthanized on days 7, 14 and 21 and submitted to histomorphometric analysis. RESULTS: In both groups the growth plate was radiographically visible at all moments from both craniocaudal and mediolateral views. On the 21st day percentage of femoral longitudinal length was higher in G2 than G1 compared to basal value while hypertrophic zone chondrocyte numbers were higher in G1 than G2. Calcified cartilage zone was greater in G1 than in G2 at all evaluation moments. Angiogenesis was higher in G1 than in G2 at 14th and 21st days. CONCLUSION: The low-level laser therapy negatively influenced the distal femoral growth plate.


2016 ◽  
Vol 79 (4) ◽  
pp. 313-320 ◽  
Author(s):  
Patricia Brassolatti ◽  
Paulo Sérgio Bossini ◽  
Maria Carolina Derêncio Oliveira ◽  
Hueliton Wilian Kido ◽  
Carla Roberta Tim ◽  
...  

Author(s):  
Luiz Guilherme Martins Maia ◽  
Angela Valéria Farias Alves ◽  
Talita Santos Bastos ◽  
Lucas Sandes Moromizato ◽  
Isabel Bezerra Lima-Verde ◽  
...  

2019 ◽  
Vol 5 (2) ◽  
pp. 55-60
Author(s):  
Juliana Sobral Antunes ◽  
Jhenifer Karvat ◽  
Giovanni Ribeiro Bernardino ◽  
Camila Mayumi Martin Kakihata ◽  
Rose Meire Costa Brancalhão ◽  
...  

2020 ◽  
Vol 11 (3) ◽  
pp. 262-267
Author(s):  
Gabriel Francisco Krueger ◽  
Milene Castilhos de Oliveira ◽  
Humberto Thomazi Gassen ◽  
Juliana Tomaz Sganzerla ◽  
Daniel Simon ◽  
...  

Introduction: This experimental study investigated the mRNA expression of aquaporins (AQPs) 1 and 5 in the parotid glands of rats irradiated with volumetric modulated arc therapy (VMAT) and subjected to low-level laser therapy (LLLT) at different time points. Methods: The sample consisted of 30 Wistar rats (Rattus norvegicus) divided into the following groups: control, LLLT alone (LG), radiotherapy alone (RG), and experimental groups that received LLLT at 24 hours (early experimental group [EEG], n=12) and 120 hours (late experimental group [LEG], n=12) after radiotherapy. VMAT was delivered at a single dose (12 Gy) and LLLT was performed with an aluminium-gallium-arsenide diode laser (660 nm, 100 mW), spot area of 0.0028 cm2, energy of 2 J/cm2 applied to 3 spots in the region corresponding to the right parotid gland, for 10 consecutive days. The right parotid gland was resected and prepared for RNA extraction. The gene expression of AQPs was evaluated by quantitative polymerase chain reaction (qPCR) using specific TaqMan probes, with the HPRT gene as an internal control. Results: The lowest AQP1 gene expression was 0.83 (0.27) with the use of LLLT 24 hours after radiotherapy (EEG), and the highest was 1.56 (0.80) with the use of LLLT alone (LG). Likewise, the lowest AQP5 gene expression was found in the EEG (mean = 0.88; SD = 0.49) and the highest in the LG (mean = 1.29; SD = 0.33). Conclusion: The use of LLLT after radiotherapy may contribute to the maintenance and an increase of these proteins, even when used at a later time point after radiotherapy.


2020 ◽  
Vol 11 (3) ◽  
pp. 348-354
Author(s):  
Milena Gomes Melo Leite ◽  
Eliandro de Souza Freitas ◽  
Antonio Jorge Araújo de Vasconcelos II ◽  
Tiago Novaes Pinheiro

Introduction: Necrotizing sialometaplasia (NS) is a rare locally destructive inflammatory benign disease that commonly affects the minor salivary glands. It is frequently associated with the glands located in the posterior portion of the hard and soft palates. Low-level laser therapy (LLLT), also called photobiomodulation therapy (PBMT), has been deemed a substantial method for the regenerative wound process. Case Presentation: A 32-year-old male patient was referred with a chief complaint of two asymptomatic crater-like ulcers measuring approximately 1.5 cm wide on the right side of the hard and soft palates, and another measuring 0.3 cm wide on the left side of the hard palate. The lesion had two weeks of evolution followed by a previous infectious "sore throat" event that kept the patient hospitalized for 4 days. A clinical diagnosis of NS was made. LLLT was applied during 2 sessions per week, favoring the total wound healing within 2 weeks. At 3 months of clinical followup, the patient did not present any complication or relapse and was thus released. Conclusion: This is, to our knowledge, the first clinical report of LLLT applied for the management of NS. Large palatal ulcers caused by NS usually have long healing periods. The shortened healing period observed in this case encourages the inclusion of LLLT in any treatment protocol for similar lesions.


2011 ◽  
Vol 26 (4) ◽  
pp. 539-543 ◽  
Author(s):  
Humberto Osvaldo Schwartz-Filho ◽  
Aline C. Reimer ◽  
Claudio Marcantonio ◽  
Elcio Marcantonio ◽  
Rosemary Adriana C. Marcantonio

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