scholarly journals BIDS Apps: Improving ease of use, accessibility, and reproducibility of neuroimaging data analysis methods

2016 ◽  
Author(s):  
Krzysztof J. Gorgolewski ◽  
Fidel Alfaro-Almagro ◽  
Tibor Auer ◽  
Pierre Bellec ◽  
Mihai Capotă ◽  
...  

AbstractThe rate of progress in human neurosciences is limited by the inability to easily apply a wide range of analysis methods to the plethora of different datasets acquired in labs around the world. In this work, we introduce a framework for creating, testing, versioning and archiving portable applications for analyzing neuroimaging data organized and described in compliance with the Brain Imaging Data Structure (BIDS). The portability of these applications (BIDS Apps) is achieved by using container technologies that encapsulate all binary and other dependencies in one convenient package. BIDS Apps run on all three major operating systems with no need for complex setup and configuration and thanks to the comprehensiveness richness of the BIDS standard they require little manual user input. Previous containerized data processing solutions were limited to single user environments and not compatible with most multi-tenant High Performance Computing systems. BIDS Apps overcome this limitation by taking advantage of the Singularity container technology. As a proof of concept, this work is accompanied by 22 ready to use BIDS Apps, packaging a diverse set of commonly used neuroimaging algorithms.Author SummaryMagnetic Resonance Imaging (MRI) is a non-invasive way to measure human brain structure and activity that has been used for over 25 years. There are thousands MRI studies performed every year generating a substantial amount of data. At the same time, many new data analysis methods are being developed every year. The potential of using new analysis methods on the variety of existing and newly acquired data is hindered by difficulties in software deployment and lack of support for standardized input data. Here we propose to use container technology to make deployment of a wide range of data analysis techniques easy. In addition, we adapt the existing data analysis tools to interface with data organized in a standardized way. We hope that this approach will enable researchers to access a wider range of methods when analyzing their data which will lead to accelerated progress in human neuroscience.

2017 ◽  
Vol 13 (3) ◽  
pp. e1005209 ◽  
Author(s):  
Krzysztof J. Gorgolewski ◽  
Fidel Alfaro-Almagro ◽  
Tibor Auer ◽  
Pierre Bellec ◽  
Mihai Capotă ◽  
...  

2013 ◽  
Vol 13 (1) ◽  
pp. 463-486 ◽  
Author(s):  
J. Leppä ◽  
S. Gagné ◽  
L. Laakso ◽  
H. E. Manninen ◽  
K. E. J. Lehtinen ◽  
...  

Abstract. The fraction of charged nucleation mode particles as a function of particle diameter depends on the particle growth rate and the proportion of particles formed via ion-induced nucleation. In this study we have tested the applicability of recent data analysis methods to determine the growth rate and the proportion of ion-induced nucleation from the measured charged fractions. For this purpose we have conducted a series of aerosol dynamic simulations covering a wide range of atmospheric conditions. The growth rate and initial fraction of charged particles were estimated from simulated data using these methods and compared with the values obtained directly from the simulations. We found that the data analysis methods used in this study should not be used when the nuclei growth rate is less than ~3 nm h−1, or when charged particles grow much more rapidly than neutral ones. Furthermore, we found that the difference in removal rates of neutral and charged particles should be taken into account when estimating the proportion of ion-induced nucleation. Neglecting the higher removal rate of charged particles compared with that of neutral ones could result in an underestimation of the proportion of ion-induced nucleation by up to a factor of 2. This underestimation is further increased if charged particles grow more rapidly than neutral ones. We also provided a simple way of assessing whether these methods are suitable for analyzing data measured under specific conditions. The assessment procedure was illustrated using a few examples of actual measurement sites with a more detailed examination of the typical conditions observed at the SMEAR II station in Hyytiälä, Finland.


2012 ◽  
Vol 12 (8) ◽  
pp. 21867-21922
Author(s):  
J. Leppä ◽  
S. Gagné ◽  
L. Laakso ◽  
H. E. Manninen ◽  
K. E. J. Lehtinen ◽  
...  

Abstract. The fraction of charged nucleation mode particles as a function of particle diameter depends on the particle growth rate and the proportion of particles formed via ion-induced nucleation. In this study we have tested the applicability of recent data analysis methods to determine the growth rate and the proportion of ion-induced nucleation from the measured charged fractions. For this purpose we have conducted a series of aerosol dynamic simulations covering a wide range of atmospheric conditions. The growth rate and initial fraction of charged particles were estimated from simulated data using these methods and compared with the values obtained directly from the simulations. We found that the available data analysis methods should not be used when the nuclei growth rate is less than ~3 nm h−1, or when charged particles grow much more rapidly than neutral ones. Furthermore, we found that the difference in removal rates of neutral and charged particles should be taken into account when estimating the proportion of ion-induced nucleation. Neglecting the higher removal rate of charged particles compared with that of neutral ones could result in an under estimation of the proportion of ion-induced nucleation by up to a factor of 2. This under estimation is further increased if charged particles grow more rapidly than neutral ones. We also provided a simple way of assessing whether these methods are suitable for analyzing data measured under specific conditions. The assessment procedure was illustrated using a few examples of actual measurement sites with a more detailed examination of the typical conditions observed at the SMEAR II station in Hyytiälä, Finland.


2017 ◽  
Vol 9 (33) ◽  
pp. 4783-4789 ◽  
Author(s):  
Samuel Mabbott ◽  
Yun Xu ◽  
Royston Goodacre

Reproducibility of SERS signal acquired from thin films developed in-house and commercially has been assessed using seven data analysis methods.


Sign in / Sign up

Export Citation Format

Share Document