Health Economic Studies of Colorectal Cancer and the Contribution of Administrative Data: a Systematic Review

Introduction: Several forces are contributing to an increase in the number of people living with and surviving colorectal cancer (CRC). However, due to the lack of available data, little is known about those implications. In recent years, the use of administrative records to inform research has been increasing. The aim of this paper is to investigate the potential contribution that administrative data could have on the health economic research of CRC. Methods: To achieve this aim we conducted a systematic review of the health economic CRC literature published in the United Kingdom and Europe within the last decade (2009-2019). Results: Thirty-seven relevant studies were identified and divided into economic evaluations, cost of illness studies and cost consequence analyses. Conclusions: The use of administrative data, including cancer registry, screening and hospital records, within the health economic research of CRC is commonplace. However, we found that this data often comes from regional databases, which reduces the generalisability of results. Further, administrative data appear less able to contribute towards understanding the wider and indirect costs associated with the disease. We have identified several ways in which various sources of administrative data could enhance future research in this area.

Download Full-text

Economic Burden of Mental Disorders in Bangladesh: A Systematic Review and Recommendations for Future Research

10.31235/osf.io/mq9au ◽

2020 ◽

Author(s):

Tahmina Tasnim Rodela ◽

Samia Tasnim ◽

Hoimonty Mazumder ◽

Dilruba Fatima Sharmin ◽

Farah Faizah ◽

...

Keyword(s):

Mental Health ◽

Systematic Review ◽

Health Economic ◽

Mental Disorders ◽

Economic Burden ◽

Mental Health Problems ◽

Economic Research ◽

Current Evidence ◽

Future Research ◽

Health Economic Research

Mental disorders are highly prevalent in different population groups in Bangladesh. Effective policymaking and evaluation may need economic evidence on complex mental health problems. In this systematic review, we aimed to evaluate the current evidence on the economic burden of mental disorders in Bangladesh. We searched six major databases and additional sources using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We included studies that were published in English, as peer-reviewed articles, reported any economic burden of any mental disorders, and focused on the Bangladeshi population. Among a total of 1241 citations, no study met our criteria. This scarcity of evidence on the economic burden of mental disorders can be attributable to many factors, including a suboptimal state of research in mental health, lack of institutional and national priorities on mental health economic research, and lack of capacities or resources to improve knowledge. Future efforts should aim at strengthening research capacities, providing resources, prioritizing mental health research, improving collaboration, and effective policymaking and strategic planning to promote mental health economic research in the context of Bangladesh.

Download Full-text

A systematic review of health economic evaluations in orthotics and prosthetics: Part 1 – prosthetics

Prosthetics and Orthotics International ◽

10.1177/0309364620935310 ◽

2020 ◽

pp. 030936462093531

Author(s):

Leigh Clarke ◽

Michael P Dillon ◽

Alan Shiell

Keyword(s):

Systematic Review ◽

Health Economic ◽

Economic Evaluation ◽

Current Literature ◽

Health Economic Evaluation ◽

Investment Decisions ◽

Future Research ◽

Economic Evaluations ◽

Policy Makers ◽

Wide Range

Background: The extent to which current prosthetic health economic evaluations inform healthcare policy and investment decisions is unclear. To further the knowledge in this area, existing evidence gaps and method design issues must be identified, thereby informing the design of future research. Objectives: The aim of this systematic review was to identify evidence gaps, critical method design and reporting issues and determine the extent to which the literature informs a wide range of policy and investment decisions. Study Design: Systematic review. Methods: A range of databases were searched using intervention- and health economic evaluation-related terms. Issues with methodological design and reporting were evaluated using the Consolidated Health Economic Checklist – Extended and the Checklist for Health Economic Evaluation Reporting Standards. Results: The existing health economic evaluation literature was narrowly focused on informing within-participant component decisions. There were common method design (e.g. time horizon too short) and reporting issues (e.g. competing intervention descriptions) that limit the extent to which this literature can inform policy and investment decisions. Conclusion: There are opportunities to conduct a wider variety of health economic evaluations to support within- and across-sector policy and investment decisions. Changes to aspects of the method design and reporting are encouraged for future research in order to improve the rigour of the health economic evaluation evidence. Clinical relevance This systematic review will inform the clinical focus and method design of future prosthetic health economic evaluations. It will also guide readers and policy-makers in their interpretation of the current literature and their understanding of the extent to which the current literature can be used to inform policy and investment decisions.

Download Full-text

A Systematic Review of Models Used in Cost-Effectiveness of Treatments in Spondyloarthritis

Medical Research Archives ◽

10.18103/mra.v9i6.2446 ◽

2021 ◽

Vol 9 (6) ◽

Author(s):

Liudan Tu ◽

Ya Xie ◽

Jieruo Gu

Keyword(s):

Systematic Review ◽

Health Economic ◽

Cost Effectiveness ◽

Time Horizon ◽

Evaluation Studies ◽

Health Economic Evaluation ◽

Indirect Costs ◽

Economic Models ◽

Economic Evaluations

This review was aimed to evaluate health economic models used in evaluations of different treatment strategies in spondyloarthritis (SpA). Model-based health economic evaluation studies are increasing and complex models with short-term and long-term horizon are applied to investigate the cost-effectiveness of SpA treatments. The objective of this study was to carry out a systematic review of the evolution of health economic models used in the treatment of SpA. Electronic searches within MEDLINE and EMBASE were carried out using a predefined search strategy. Inclusion and exclusion criteria were used to select relevant studies. Data on country, intervention, evaluation perspective, type of model, time horizon, types of costs and effectiveness measurement were extracted. Eighteen models were described in 22 publications, of which 81.8% were European. Study perspectives included the societal (n=6), healthcare system and payer (n=14), or patient and government (n=1). Time horizon ranged from 52 weeks to lifetime. Markov model was the most frequently used model, only one individual patient simulation models accounting for uncertainty in multiple parameters was reported. Most studies compared different biologics (including different TNFi/biosimilar and IL-17A antibody) with conventional care (NSAIDs) because of the high prize. Only half of studies took indirect costs into account. Modeling is of importance in health economic evaluations of SpA treatment. Long-term costs especially indirect costs should be considered when comparing different treatment alternatives in order to provide more information for policy makers and clinicians.

Download Full-text