scholarly journals Reinforcing neuron extraction and spike inference in calcium imaging using deep self-supervised learning

2020 ◽  
Author(s):  
Xinyang Li ◽  
Guoxun Zhang ◽  
Jiamin Wu ◽  
Yuanlong Zhang ◽  
Zhifeng Zhao ◽  
...  

ABSTRACTCalcium imaging is inherently susceptible to detection noise especially when imaging with high frame rate or under low excitation dosage. We developed DeepCAD, a self-supervised learning method for spatiotemporal enhancement of calcium imaging without requiring any high signal-to-noise ratio (SNR) observations. Using this method, detection noise can be effectively suppressed and the imaging SNR can be improved more than tenfold, which massively improves the accuracy of neuron extraction and spike inference and facilitate the functional analysis of neural circuits.

2014 ◽  
Vol 74 (6) ◽  
pp. 1587-1597 ◽  
Author(s):  
Mitchell A. Cooper ◽  
Thanh D. Nguyen ◽  
Bo Xu ◽  
Martin R. Prince ◽  
Michael Elad ◽  
...  

2019 ◽  
Vol 42 (1) ◽  
pp. 27-40 ◽  
Author(s):  
Hideyuki Hasegawa ◽  
Ryo Nagaoka

High-frame-rate ultrasound is an emerging technique for functional ultrasound imaging. However, the lateral spatial resolution and contrast in high-frame-rate ultrasound with an unfocused transmit beam are inherently lower than those in conventional ultrasonic imaging based on the line-by-line acquisition using a focused ultrasonic beam because of the low directivity of the transmit beam. Coherence-based beamforming methods were introduced in ultrasound imaging for improvement of image quality. Such methods improve the lateral spatial resolution using the coherence among ultrasonic echo signals received by individual transducer elements. In this study, a new method based on the signal-to-noise ratio (SNR) among the element echo signals was developed for enhancement of the effect of the coherence factor (CF), which was previously developed for improvement in spatial resolution and contrast. In the proposed method, a new factor, namely, SNR factor, was introduced, and the relationship between the previously developed CF and SNR factor was discussed. The proposed method was implemented in plane wave imaging, and the performance was evaluated by simulated and phantom experiments. In simulation, the lateral spatial resolution and contrast obtained with the conventional CF were 0.23 mm and 47.0 dB, respectively, which were significantly better than 0.39 mm and 15.3 dB obtained by conventional delay-and-sum (DAS) beamforming. Using the proposed method, the lateral spatial resolution and contrast were further improved to 0.12 mm and 69.8 dB, respectively. Similar trends were found also in phantom experiments.


2020 ◽  
Vol 64 (1-4) ◽  
pp. 951-958
Author(s):  
Tianhao Liu ◽  
Yu Jin ◽  
Cuixiang Pei ◽  
Jie Han ◽  
Zhenmao Chen

Small-diameter tubes that are widely used in petroleum industries and power plants experience corrosion during long-term services. In this paper, a compact inserted guided-wave EMAT with a pulsed electromagnet is proposed for small-diameter tube inspection. The proposed transducer is noncontact, compact with high signal-to-noise ratio and unattractive to ferromagnetic tubes. The proposed EMAT is designed with coils-only configuration, which consists of a pulsed electromagnet and a meander pulser/receiver coil. Both the numerical simulation and experimental results validate its feasibility on generating and receiving L(0,2) mode guided wave. The parameters for driving the proposed EMAT are optimized by performance testing. Finally, feasibility on quantification evaluation for corrosion defects was verified by experiments.


Nanophotonics ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 3443-3450 ◽  
Author(s):  
Wei-Nan Liu ◽  
Rui Chen ◽  
Wei-Yi Shi ◽  
Ke-Bo Zeng ◽  
Fu-Li Zhao ◽  
...  

AbstractSelective transmission or filtering always responds to either frequency or incident angle, so as hardly to maximize signal-to-noise ratio in communication, detection and sensing. Here, we propose compact meta-filters of narrow-frequency sharp-angular transmission peak along with broad omnidirectional reflection sidebands, in all-dielectric cascaded subwavelength meta-gratings. The inherent collective resonance of waveguide-array modes and thin film approximation of meta-grating are employed as the design strategy. A unity transmission peak, locating at the incident angle of 44.4° and the center wavelength of 1550 nm, is demonstrated in a silicon meta-filter consisting of two-layer silicon rectangular meta-grating. These findings provide possibilities in cascaded meta-gratings spectroscopic design and alternative utilities for high signal-to-noise ratio applications in focus-free spatial filtering and anti-noise systems in telecommunications.


2016 ◽  
Vol 7 (2) ◽  
pp. 381 ◽  
Author(s):  
Lukas B. Gromann ◽  
Dirk Bequé ◽  
Kai Scherer ◽  
Konstantin Willer ◽  
Lorenz Birnbacher ◽  
...  

2014 ◽  
Vol 556-562 ◽  
pp. 6328-6331
Author(s):  
Su Zhen Shi ◽  
Yi Chen Zhao ◽  
Li Biao Yang ◽  
Yao Tang ◽  
Juan Li

The LIFT technology has applied in process of denoising to ensure the imaging precision of minor faults and structure in 3D coalfield seismic processing. The paper focused on the denoising process in two study areas where the LIFT technology is used. The separation of signal and noise is done firstly. Then denoising would be done in the noise data. The Data of weak effective signal that is from the noise data could be blended with the original effective signal to reconstruct the denoising data, so the result which has high signal-to-noise ratio and preserved amplitude is acquired. Thus the fact shows that LIFT is an effective denoising method for 3D seismic in coalfield and could be used widely in other work area.


2013 ◽  
Vol 770 ◽  
pp. 319-322 ◽  
Author(s):  
Piya Kovintavewat ◽  
Santi Koonkarnkhai ◽  
Aimamorn Suvichakorn

During hard disk drive (HDD) testing process, the magneto-resistive read (MR) head is analyzed and checked if the head is defective or not. Baseline popping (BLP) is one of the crucial problems caused by head instability, whose effect can distort the readback signal to the extent of causing possible sector read failure. Without BLP detection algorithm, the defective read head might pass through HDD assembling process, thus producing an unreliable HDD. This situation must be prevented so as to retain customer satisfaction. This paper proposes a simple (but efficient) BLP detection algorithm for perpendicular magnetic recording systems. Results show that the proposed algorithm outperforms the conventional one in terms of both the percentage of detection and the percentage of false alarm, when operating at high signal-to-noise ratio.


2006 ◽  
Author(s):  
Stanley Wissmar ◽  
Linda Höglund ◽  
Jan Andersson ◽  
Christian Vieider ◽  
Susan Savage ◽  
...  

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