scholarly journals Multiple macroecological laws do characterize various aspects of microbiota dynamics

2021 ◽  
Author(s):  
Konstantine Tchourine ◽  
Martin Carballo-Pacheco ◽  
Dennis Vitkup

In this letter we address the potential confusion related to our recent demonstration that multiple macroecological laws describe short- and long-term dynamics of microbial communities. Specifically, we clarify that these laws, similarly to many other relationships observed in nature, are characterized not just by the existence of scaling, but also by certain characteristic values of the scaling exponents. By performing proper statistical analysis, we demonstrate that the relationships sensitive to temporal bacterial dynamics are not reproduced in the shuffled data. We also discuss that there is no clear evidence in the data that macroecological relationships in microbiota are primarily driven by external or environmental factors. Proper statistical analyses of the data suggest that the dynamics of gut microbiota, even on a constant diet, contains rich temporal structure. Therefore, it is likely that complex and non-linear internal dynamics may be primarily responsible for the observed macroecological laws in microbiota and other ecological communities.

1994 ◽  
Vol 103 (12) ◽  
pp. 945-951 ◽  
Author(s):  
Thomas Somers ◽  
Thérèse Marquet ◽  
Paul Govaerts ◽  
Erwin Offeciers

The early and long-term hearing results of 1,681 primary otosclerosis operations performed by the same surgeon, Jean Marquet, were reviewed retrospectively and analyzed with very strict statistical standards. Significantly better short- and long-term results were achieved with the stapedotomy technique compared to total stapedectomy, mainly at the higher frequencies (4 and 8 kHz) important for speech discrimination. Whatever technique was used to open the footplate (micropick, microdrill, or laser), no statistical audiometric difference could be found. The results were equal whether or not the stapedial tendon was preserved. Perioperative problems like pronounced oozing, difficult anatomic relationships, and accidental perilymph aspiration could affect hearing at higher frequencies. The calibrated hole technique was equally as good as conventional oval window sealing in sealing of the fenestra to prevent fistula. The stapedotomy technique was found the safest, having fewer complications.


2011 ◽  
Vol 45 (1) ◽  
pp. 43-51 ◽  
Author(s):  
Mario N. Tamburri ◽  
Thomas H. Johengen ◽  
Marlin J. Atkinson ◽  
Daniel W. H. Schar ◽  
Charles Y. Robertson ◽  
...  

AbstractThe Alliance for Coastal Technologies (ACT) has been established to support innovation and to provide the information required to select the most appropriate tools for studying and monitoring coastal and ocean environments. ACT is a consortium of nationally prominent ocean science and technology institutions and experts who provide credible performance data of these technologies through third-party, objective testing. ACT technology verifications include laboratory and field tests over short- and long-term deployments of commercial technologies in diverse environments to provide unequivocal, unbiased confirmation that technologies meet key performance requirements. ACT demonstrations of new technologies validate the technology concept and help eliminate performance problems before operational introduction. ACT’s most recent demonstration of pCO2 sensors is an example of how ACT advances the evolution of ocean observing technologies, in this case to address the critical issue of ocean acidification, and promotes more informed decision making on technology capabilities and choices.


2022 ◽  
Author(s):  
Allen Rubin

Win probabilities have become a staple on scoreboards in physical sports such as baseball and basketball. Esports, or competitive video games with sponsored teams and major audiences, typically lack this detailed statistical analysis, beyond bare-bones metrics and commentator intuition. However, the advantage of esports in their tendency to have a central record of every game event makes them ripe for statistical analysis through machine learning. Previous research has covered popular video game genres such as MOBAs, and has found success in predicting game winners most of the time [1]. Counterstrike: Global Offensive (CSGO) is an esport that is unique in its round and game-based nature, allowing researchers to examine how short and long-term decisions can interplay in competitive environments. We introduce a dataset of CSGO games To assess factors such as player purchasing decisions and individual scores, we introduce 3 round and game win probability models. Finally, we evaluate the performances of the models. We successfully predict winners in the majority of cases, better than the map average baseline win statistics.


Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Robert ◽  
Mariéthoz ◽  
Pache ◽  
Bertin ◽  
Caulfield ◽  
...  

Objective: Approximately one out of five patients with Graves' disease (GD) undergoes a thyroidectomy after a mean period of 18 months of medical treatment. This retrospective and non-randomized study from a teaching hospital compares short- and long-term results of total (TT) and subtotal thyroidectomies (ST) for this disease. Methods: From 1987 to 1997, 94 patients were operated for GD. Thirty-three patients underwent a TT (mostly since 1993) and 61 a ST (keeping 4 to 8 grams of thyroid tissue - mean 6 g). All patients had received propylthiouracil and/or neo-mercazole and were in a euthyroid state at the time of surgery; they also took potassium iodide (lugol) for ten days before surgery. Results: There were no deaths. Transient hypocalcemia (< 3 months) occurred in 32 patients (15 TT and 17 ST) and persistent hypocalcemia in 8 having had TT. Two patients developed transient recurrent laryngeal nerve palsy after ST (< 3 months). After a median follow-up period of seven years (1-15) with five patients lost to follow-up, 41 patients having had a ST are in a hypothyroid state (73%), thirteen are euthyroid (23%), and two suffered recurrent hyperthyroidism, requiring completion of thyroidectomy. All 33 patients having had TT - with follow-ups averaging two years (0.5-8) - are receiving thyroxin substitution. Conclusions: There were no instances of persistent recurrent laryngeal nerve palsy in either group, but persistent hypoparathyroidism occurred more frequently after TT. Long after ST, hypothyroidism developed in nearly three of four cases, whereas euthyroidy was maintained in only one-fourth; recurrent hyperthyroidy was rare.


Author(s):  
Ian Neath ◽  
Jean Saint-Aubin ◽  
Tamra J. Bireta ◽  
Andrew J. Gabel ◽  
Chelsea G. Hudson ◽  
...  

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