scholarly journals Neural language processing across time, space, frequency and age: MEG-MVPA classification of intertrial phase coherence

2021 ◽  
Author(s):  
Mads Jensen ◽  
Rasha Hyder ◽  
Britta U. Westner ◽  
Andreas Højlund ◽  
Yury Shtyrov

AbstractLanguage is a key part of human cognition. Whereas many neurocognitive abilities decline with age, for language the picture is much less clear and how exactly language processing changes with aging is still unknown. To investigate this, we employed magnetoencephalography (MEG) and recorded neuromagnetic brain responses to auditory linguistic stimuli in healthy participants of younger and older age using a passive task-free paradigm and a range of different linguistic stimulus contrasts, which enabled us to assess neural language processes at multiple levels (lexical, semantic, morphosyntactic). By using machine learning-based classification algorithms to scrutinise intertrial phase coherence of MEG responses in source space, we found significant differences between younger and older participants across several frequency bands and for all tested processing types, which shows multiple changes in the brain’s neurolinguistic circuits which may be due to both healthy aging in general and compensatory processes in particular.

Author(s):  
Anil K. Seth

Consciousness is perhaps the most familiar aspect of our existence, yet we still do not know its biological basis. This chapter outlines a biomimetic approach to consciousness science, identifying three principles linking properties of conscious experience to potential biological mechanisms. First, conscious experiences generate large quantities of information in virtue of being simultaneously integrated and differentiated. Second, the brain continuously generates predictions about the world and self, which account for the specific content of conscious scenes. Third, the conscious self depends on active inference of self-related signals at multiple levels. Research following these principles helps move from establishing correlations between brain responses and consciousness towards explanations which account for phenomenological properties—addressing what can be called the “real problem” of consciousness. The picture that emerges is one in which consciousness, mind, and life, are tightly bound together—with implications for any possible future “conscious machines.”


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tuan D. Pham

AbstractAutomated analysis of physiological time series is utilized for many clinical applications in medicine and life sciences. Long short-term memory (LSTM) is a deep recurrent neural network architecture used for classification of time-series data. Here time–frequency and time–space properties of time series are introduced as a robust tool for LSTM processing of long sequential data in physiology. Based on classification results obtained from two databases of sensor-induced physiological signals, the proposed approach has the potential for (1) achieving very high classification accuracy, (2) saving tremendous time for data learning, and (3) being cost-effective and user-comfortable for clinical trials by reducing multiple wearable sensors for data recording.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Olga Majewska ◽  
Charlotte Collins ◽  
Simon Baker ◽  
Jari Björne ◽  
Susan Windisch Brown ◽  
...  

Abstract Background Recent advances in representation learning have enabled large strides in natural language understanding; However, verbal reasoning remains a challenge for state-of-the-art systems. External sources of structured, expert-curated verb-related knowledge have been shown to boost model performance in different Natural Language Processing (NLP) tasks where accurate handling of verb meaning and behaviour is critical. The costliness and time required for manual lexicon construction has been a major obstacle to porting the benefits of such resources to NLP in specialised domains, such as biomedicine. To address this issue, we combine a neural classification method with expert annotation to create BioVerbNet. This new resource comprises 693 verbs assigned to 22 top-level and 117 fine-grained semantic-syntactic verb classes. We make this resource available complete with semantic roles and VerbNet-style syntactic frames. Results We demonstrate the utility of the new resource in boosting model performance in document- and sentence-level classification in biomedicine. We apply an established retrofitting method to harness the verb class membership knowledge from BioVerbNet and transform a pretrained word embedding space by pulling together verbs belonging to the same semantic-syntactic class. The BioVerbNet knowledge-aware embeddings surpass the non-specialised baseline by a significant margin on both tasks. Conclusion This work introduces the first large, annotated semantic-syntactic classification of biomedical verbs, providing a detailed account of the annotation process, the key differences in verb behaviour between the general and biomedical domain, and the design choices made to accurately capture the meaning and properties of verbs used in biomedical texts. The demonstrated benefits of leveraging BioVerbNet in text classification suggest the resource could help systems better tackle challenging NLP tasks in biomedicine.


2021 ◽  
Vol 11 (8) ◽  
pp. 960
Author(s):  
Mina Kheirkhah ◽  
Philipp Baumbach ◽  
Lutz Leistritz ◽  
Otto W. Witte ◽  
Martin Walter ◽  
...  

Studies investigating human brain response to emotional stimuli—particularly high-arousing versus neutral stimuli—have obtained inconsistent results. The present study was the first to combine magnetoencephalography (MEG) with the bootstrapping method to examine the whole brain and identify the cortical regions involved in this differential response. Seventeen healthy participants (11 females, aged 19 to 33 years; mean age, 26.9 years) were presented with high-arousing emotional (pleasant and unpleasant) and neutral pictures, and their brain responses were measured using MEG. When random resampling bootstrapping was performed for each participant, the greatest differences between high-arousing emotional and neutral stimuli during M300 (270–320 ms) were found to occur in the right temporo-parietal region. This finding was observed in response to both pleasant and unpleasant stimuli. The results, which may be more robust than previous studies because of bootstrapping and examination of the whole brain, reinforce the essential role of the right hemisphere in emotion processing.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tuan D. Pham

AbstractImage analysis in histopathology provides insights into the microscopic examination of tissue for disease diagnosis, prognosis, and biomarker discovery. Particularly for cancer research, precise classification of histopathological images is the ultimate objective of the image analysis. Here, the time-frequency time-space long short-term memory network (TF-TS LSTM) developed for classification of time series is applied for classifying histopathological images. The deep learning is empowered by the use of sequential time-frequency and time-space features extracted from the images. Furthermore, unlike conventional classification practice, a strategy for class modeling is designed to leverage the learning power of the TF-TS LSTM. Tests on several datasets of histopathological images of haematoxylin-and-eosin and immunohistochemistry stains demonstrate the strong capability of the artificial intelligence (AI)-based approach for producing very accurate classification results. The proposed approach has the potential to be an AI tool for robust classification of histopathological images.


2006 ◽  
Vol 15 (5) ◽  
pp. 500-514 ◽  
Author(s):  
Robert Leeb ◽  
Claudia Keinrath ◽  
Doron Friedman ◽  
Christoph Guger ◽  
Reinhold Scherer ◽  
...  

Healthy participants are able to move forward within a virtual environment (VE) by the imagination of foot movement. This is achieved by using a brain-computer interface (BCI) that transforms thought-modulated electroencephalogram (EEG) recordings into a control signal. A BCI establishes a communication channel between the human brain and the computer. The basic principle of the Graz-BCI is the detection and classification of motor-imagery-related EEG patterns, whereby the dynamics of sensorimotor rhythms are analyzed. A BCI is a closed-loop system and information is visually fed back to the user about the success or failure of an intended movement imagination. Feedback can be realized in different ways, from a simple moving bar graph to navigation in VEs. The goals of this work are twofold: first, to show the influence of different feedback types on the same task, and second, to demonstrate that it is possible to move through a VE (e.g., a virtual street) without any muscular activity, using only the imagination of foot movement. In the presented work, data from BCI feedback displayed on a conventional monitor are compared with data from BCI feedback in VE experiments with a head-mounted display (HMD) and in a high immersive projection environment (Cave). Results of three participants are reported to demonstrate the proof-of-concept. The data indicate that the type of feedback has an influence on the task performance, but not on the BCI classification accuracy. The participants achieved their best performances viewing feedback in the Cave. Furthermore the VE feedback provided motivation for the subjects.


2018 ◽  
Vol 4 (11) ◽  
pp. eaar8334 ◽  
Author(s):  
M. Winkler ◽  
J. L. Mueller ◽  
A. D. Friederici ◽  
C. Männel

Human cognition relies on the ability to encode complex regularities in the input. Regularities above a certain complexity level can involve the feature of embedding, defined by nested relations between sequential elements. While comparative studies suggest the cognitive processing of embedding to be human specific, evidence of its ontogenesis is lacking. To assess infants’ ability to process embedding, we implemented nested relations in tone sequences, minimizing perceptual and memory requirements. We measured 5-month-olds’ brain responses in two auditory oddball paradigms, presenting standard sequences with one or two levels of embedding, interspersed with infrequent deviant sequences violating the established embedding rules. Brain potentials indicate that infants detect embedding violations and thus appear to track nested relations. This shows that the ability to encode embedding may be part of the basic human cognitive makeup, which might serve as scaffolding for the acquisition of complex regularities in language or music.


Author(s):  
Neha Thomas ◽  
Susan Elias

 Abstract— Detection of fake review and reviewers is currently a challenging problem in cyber space. It is challenging primarily due to the dynamic nature of the methodology used to fake the review. There are several aspects to be considered when analyzing reviews to classify them effective into genuine and fake. Sentiment analysis, opinion mining and intend mining are fields of research that try to accomplish the goal through Natural Language Processing of the text content of the review.  In this paper, an approach that uses the review ratings evaluated along a timeline is presented. An Amazon dataset comprising of ratings indicated for a wide range of products was used for the analysis presented here. The analysis of the ratings was carried out for an electronic product over a period of six years.  The computed average rating helps to identify linear classifiers that define solution boundaries within the dataspace. This enables a product specific classification of review ratings and suitable recommendations can also be generated automatically. The paper explains a methodology to evaluate the average product ratings over time and presents the research outcomes using a novel classification tool. The proposed approach helps to determine the optimal point to distinguish between fake and genuine ratings for each product.    Index Terms: Fake reviews, Fake Ratings, Product Ratings, Online Shopping, Amazon Dataset.


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