Automated methodology for optimal selection of the minimum electrode subset for accurate EEG source localization based on Genetic Algorithm optimization
High-density Electroencephalography (HD-EEG) has been proven to be the most accurate option to estimate the neural activity inside the brain. Although multiple studies report the effect of electrode number on source localization for specific sources and specific electrode configurations, the electrodes for each configuration have been manually selected to uniformly cover the entire head, going from 32 to 128 electrodes, where electrodes were not selected according to their contribution to accuracy. In this work, an optimization-based study aimed to determine the minimum number of electrodes and identify optimal combinations of electrodes that can keep the localization accuracy of HD-EEG reconstructions. This optimization approach incorporates scalp landmark positions of widely used EEG montages. In this way, a systematic search for the minimum electrode subset is performed for single and multiple source localization problems. The Non-dominated Sorting Genetic Algorithm II (NSGA-II) combined with source reconstruction methods is used to formulate a multi-objective optimization problem that minimize (1) the localization error for each source and (2) the number of required EEG electrodes. It can be used for evaluating the source localization quality of low-density EEG systems (consumer-grade wearable EEG). We performed an evaluation over synthetic and real EEG dataset with known ground-truth. The experimental results shown that selected electrode combinations with 6 electrodes can obtain for a single source case, an equal or better accuracy than HD-EEG (with more than 200 channels) when reconstructing a particular brain activity in more than 88% of the cases (in synthetic signals) and 63% (in real signals), and more than 88% and 73% of the cases when considering combinations with 8 channels. For a multiple-source case of three sources (only with synthetic signals), it was found that an equal or better accuracy than HD-EEG with 231 electrodes was attained in at least 58%, 76%, and 82% of the cases, when using optimized combinations of 8, 12, and 16 electrodes, respectively. Additionally, in such electrode numbers a lower mean error and standard deviation than with 231 electrodes was obtained.