PROGRESSION OF AUTOANTIBODIES ANTI-GAD AND ANTI-IA2 IN TYPE 1A DIABETICS AGED OF 5 TO 21 YEARS IN CÔTE D’IVOIRE

AbstractBackgroundDiabetes autoantibodies are indispensable markers of diabetes classification.Objectiveto research autoantibodies anti-GAD and anti-IA2 in type 1A diabetics (T1D) aged 5 to 21 years, and to follow the progression of these autoantibodies in T1D patients, in Côte d’Ivoire.MethodsThe study population composed of 28 T1D patients, aged 5 to 21 years. T1D were followed up in two diabetes care centers in Abidjan district, Endocrinology departments of U.H.C of Yopougon and Treichville. Anti-GAD and anti-IA2 autoantibodies were researched by ELISA.Resultsanti-GAD and anti-IA2 were present in T1D and their siblings. After 2 years of diabetes, the titer of the anti-GAD autoantibodies increased to the mean value of 677.10 ± 353.20 IU / ml. Then, a fall of the anti-GAD autoantibodies until the cancellation was observed from the 8th to the 9th with values of 117 IU / ml to 10.14 IU / ml. Anti-IA2 autoantibodies fall at 9th year of diabetes with a value of 55.10 IU / ml.Conclusionanti-GAD and anti-IA2 autoantibodies persist after 9 years of diabetes, causing total destruction over time of the pancreatic β-cell mass in patients from Côte d’Ivoire, leading them to the death.

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Use of vector control to protect people from sleeping sickness in the focus of Bonon (Côte d’Ivoire)

PLoS Neglected Tropical Diseases ◽

10.1371/journal.pntd.0009404 ◽

2021 ◽

Vol 15 (6) ◽

pp. e0009404

Author(s):

Dramane Kaba ◽

Vincent Djohan ◽

Djakaridja Berté ◽

Bi Tra Dieudonné TA ◽

Richard Selby ◽

...

Keyword(s):

Cote D'ivoire ◽

Côte D’Ivoire ◽

Tsetse Flies ◽

Cote D’Ivoire ◽

Tsetse Control ◽

Entomological Survey ◽

Côte D'ivoire ◽

The Mean ◽

Monitoring Traps ◽

Glossina Palpalis

Background Gambian human African trypanosomiasis (gHAT) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by tsetse flies (Glossina). In Côte d’Ivoire, Bonon is the most important focus of gHAT, with 325 cases diagnosed from 2000 to 2015 and efforts against gHAT have relied largely on mass screening and treatment of human cases. We assessed whether the addition of tsetse control by deploying Tiny Targets offers benefit to sole reliance on the screen-and-treat strategy. Methodology and principal findings In 2015, we performed a census of the human population of the Bonon focus, followed by an exhaustive entomological survey at 278 sites. After a public sensitization campaign, ~2000 Tiny Targets were deployed across an area of 130 km2 in February of 2016, deployment was repeated annually in the same month of 2017 and 2018. The intervention’s impact on tsetse was evaluated using a network of 30 traps which were operated for 48 hours at three-month intervals from March 2016 to December 2018. A second comprehensive entomological survey was performed in December 2018 with traps deployed at 274 of the sites used in 2015. Sub-samples of tsetse were dissected and examined microscopically for presence of trypanosomes. The census recorded 26,697 inhabitants residing in 331 settlements. Prior to the deployment of targets, the mean catch of tsetse from the 30 monitoring traps was 12.75 tsetse/trap (5.047–32.203, 95%CI), i.e. 6.4 tsetse/trap/day. Following the deployment of Tiny Targets, mean catches ranged between 0.06 (0.016–0.260, 95%CI) and 0.55 (0.166–1.794, 95%CI) tsetse/trap, i.e. 0.03–0.28 tsetse/trap/day. During the final extensive survey performed in December 2018, 52 tsetse were caught compared to 1,909 in 2015, with 11.6% (5/43) and 23.1% (101/437) infected with Trypanosoma respectively. Conclusions The annual deployment of Tiny Targets in the gHAT focus of Bonon reduced the density of Glossina palpalis palpalis by >95%. Tiny Targets offer a powerful addition to current strategies towards eliminating gHAT from Côte d’Ivoire.

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Calibration of Ångström-Prescott Coefficients to Estimate Global Solar Radiation in Côte d’Ivoire

European Scientific Journal ESJ ◽

10.19044/esj.2021.v17n37p24 ◽

2021 ◽

Vol 17 (37) ◽

pp. 24

Author(s):

Maurice Aka Djoman ◽

Wanignon Ferdinand Fassinou ◽

Augustin Memeledje

Keyword(s):

Solar Radiation ◽

Cote D'ivoire ◽

Côte D’Ivoire ◽

Global Solar Radiation ◽

Mean Bias Error ◽

Bias Error ◽

Cote D’Ivoire ◽

Côte D'ivoire ◽

The Mean ◽

Weather Stations

In this study, we used monthly mean daily global radiation data and sunshine durations from nine (9) weather stations in Côte d’Ivoire to determine the annual Ångström-Prescott coefficients. The calibration of the Ångström-Prescott equation has been done through linear regression using the least square method. The empirical coefficients obtained are utilized to predict the global horizontal irradiance over the nine (9) weather stations of interest. Estimated and measured global radiations were compared using the root mean square error (RMSE), the mean bias error (MBE), the mean absolute bias error (MABE), the mean percentage error (MPE), the Nash-Sutcliffe coefficient of efficiency (NSE), and the statistic -test (). The low values of the statistic t-test (from 0.10 to 1.07) and MPE (from -0.413 to 0.201) indicate a good performance of the model. The high values of the coefficient of determination R² (from 0.9776 to 0.9916) show a remarkable agreement between predicted and measured global solar radiations. This remark is also confirmed by the high values of NSE (from 0.8671 to 0.9819) closer to 1. The obtained values of MBE (from -18.17 to 8.69 kWh/m²), MABE (from 7.16 to 8.52 kWh/m²), and RMSE (69.1 to 167.3 kWh/m²) show a low deviation or bias between the estimate and the measurements. The Ångström-Prescott coefficients determinants are consistent and can be used to efficiently calculate the global horizontal irradiance. The model established can be recommended to be used in the nine (9) weather stations to accurately estimate global solar radiation on horizontal surfaces.

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Caractérisation Biochimique De La Pulpe des Fruits Du Prunier Noir (Vitex Doniana) De La Côte d’Ivoire

European Scientific Journal ESJ ◽

10.19044/esj.2018.v14n3p252 ◽

2018 ◽

Vol 14 (3) ◽

pp. 252

Author(s):

Kone Haffiata Soro ◽

Kone Kisselmina Youssouf ◽

Akaki Koffi David ◽

Soro Doudjo ◽

Elleingang Fattoh Eric ◽

...

Keyword(s):

Vitamin C ◽

Cote D'ivoire ◽

Côte D’Ivoire ◽

Low Cost ◽

Climatic Zones ◽

Cote D’Ivoire ◽

Antioxidant Power ◽

Côte D'ivoire ◽

The Mean ◽

Vitex Doniana

Black plum, the fruit of Vitex doniana, was harvested in three (3) regions belonging to different climatic zones in northern Côte d'Ivoire. Biochemical characteristics of the pulps were studied in order to highlight their nutritional potential and the variability of this composition according to study areas. From the conventional biochemical analyzes used, it appears that the fruit pulp is acidic and mostly made up of water. It is rich in sugars and has antioxidant power between 18.63 ± 0.02 and 35.54 ± 0.01 µg.mL -1. There is also the presence of polyphenols (166.67 ± 0.01 – 196.67 ± 0.01 mEq A.G./100g) and vitamin C (14.34 ± 0.02 – 15.05 ± 0.07 mg/100g). Ashes consist of minerals such as magnesium, potassium and calcium. The analysis of the variance showed that the mean of the parameters studied are significantly different from one region to the other, except the ash rate and vitamin C content. In view of its nutritional quality, black plum presents itself as an interesting fruit to be taken into account in the prevention of certain dietary imbalances and which can even intervene at low cost in the treatment of certain pathologies.

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Characterization of Agropastoral Dam Lakes in the Bounkani Region, Côte d’Ivoire

Journal of Geography Environment and Earth Science International ◽

10.9734/jgeesi/2021/v25i930305 ◽

2021 ◽

pp. 19-30

Author(s):

Ettien Yah Carine ◽

Yao Koffi Blaise ◽

Kouame Koffi Fernand ◽

Oga Yéi Marie-Solange

Keyword(s):

Cote D'ivoire ◽

Côte D’Ivoire ◽

Annual Rainfall ◽

Cote D’Ivoire ◽

North East ◽

The North ◽

East Region ◽

A Value ◽

Côte D'ivoire ◽

Sensing Technology

The North-East region (Bounkani) of Côte d'Ivoire is the least watered region of the country with an average annual rainfall of 945 mm. The rainfall deficits observed in Côte d'Ivoire since 1970s could constitute a real threat to the environment and to water resources in general, and to dam lakes in particular. The main aim of this study was to follow the evolution of the dam lakes in the region over the years, i.e,(1986, 2002 and 2017) with reference to their spatial distribution (their densities and their limnological ratios). The approach adopted consisted of mapping and monitoring through remote sensing technology which involves processing satellite images for automatic extraction of these agropastoral structures on the various images. The results showed that these dam lakes were unevenly distributed both at the level of the departments and the watersheds, with 73.43% in the Black Volta and 28.57% in the Comoé. The density was higher in Doropo and varied from one department to another from 1986 to 2017, for the department of Bouna, it ranged from 9.34.10-4 to 3.74.10-3 per km2. The departments of Doropo and Tehini showed 1.51.10-3 to 1.01.10-2 per km2 and 1.05.10-3 to 4.53.10-3 per km2 respectively. Nassian department displayed a value of 1.42.10-3 per km2 and remained constant from 2002 to 2017. Like the density, Doropo Department had the highest limnological ratio which changes from 7.09.10-5 to 2.71.10-4 per km2 over the same period. The mapping of these agropastoral structures showed 18 agropastoral structures where 57 (28.07%) were functional or even contained water in the dry season in the region in 2017 including 2 in Nassian; 4 in Tehini; 9 in Doropo and 3 in Bouna.

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Polymorphism of MMP1 and MMP3 promoter regions and HR-HPV infection in women from Burkina Faso and Côte d‘Ivoire

BioMolecular Concepts ◽

10.1515/bmc-2020-0010 ◽

2020 ◽

Vol 11 (1) ◽

pp. 116-124

Author(s):

Bado Prosper ◽

Djigma Wendkuuni Florencia ◽

Zohoncon Théodora Mahoukèdè ◽

Obiri-Yeboah Dorcas ◽

Traoré Esther Mah Alima ◽

...

Keyword(s):

Cote D'ivoire ◽

Côte D’Ivoire ◽

Hpv Infection ◽

Human Papillomaviruses ◽

Promoter Regions ◽

Single Nucleotide ◽

Cote D’Ivoire ◽

Côte D'ivoire ◽

Study Population ◽

Control Study

AbstractThe single nucleotide polymorphism (SNP) of the promoter region of MMP-1 (at 1607 bp) and MMP-3 (at 1171 bp) create Ets binding sites. Correlations between these SNPs and sensitivity to several biological processes such as metastasis and recurrence of cancer have been reported in several studies.In this case-control study, we looked for these SNPs in women infected with or not with high-risk human papillomaviruses (HR-HPV). The frequency, distribution and correlation of these SNPs with the presence or absence of HR-HPV infection were evaluated.Genotypes 1G1G, 1G2G and 2G2G for MMP1 and genotypes 5A5A, 5A6A, 6A6A for MMP3 were found in our study population. In general, we noted that the 1G (40.8%) and 2G (64.8%) alleles were more frequent in non-infected women and infected women, respectively, and more specifically this difference was significant in women from Côte d‘Ivoire.These results, although yet to be reaffirmed with assays for quantifying the mRNA of these genes, suggest that the SNP of the MMP-1 promoter could promote infection with HR-HPV.

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