In Vivo Delivery of Plasmid DNA into Rabbit Myocardium Using Polylysine Copolymers

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We report the development of targeted theragnostic lipid/peptide/DNA lipopolyplexes for delivery of both a tyrosine kinase inhibitor, and plasmid DNA coding for a biosensor. These are used to quantify EGFR inhibition in cancer cell lines in vivo.





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