scholarly journals Genetic and molecular analysis of an allelic series of cop1 mutants suggests functional roles for the multiple protein domains.

1994 ◽  
Vol 6 (4) ◽  
pp. 487-500 ◽  
Author(s):  
T W McNellis ◽  
A G von Arnim ◽  
T Araki ◽  
Y Komeda ◽  
S Miséra ◽  
...  
Keyword(s):  
Molecular Analysis ◽  
Protein Domains ◽  
Allelic Series ◽  
Functional Roles ◽  
Multiple Protein

scholarly journals Genetic and Molecular Analysis of an Allelic Series of cop1 Mutants Suggests Functional Roles for the Multiple Protein Domains

1994 ◽  
Vol 6 (4) ◽  
pp. 487 ◽  
Author(s):  
Timothy W. McNellis ◽  
Albrecht G. von Arnim ◽  
Takashi Araki ◽  
Yoshibumi Komeda ◽  
Simon Misera ◽  
...  
Keyword(s):  
Molecular Analysis ◽  
Protein Domains ◽  
Allelic Series ◽  
Functional Roles ◽  
Multiple Protein

scholarly journals Inferring Protein Domain Semantic Roles Using word2vec

2019 ◽  
Author(s):  
Daniel Buchan ◽  
David Jones
Keyword(s):  
Vector Space ◽  
Unknown Function ◽  
Protein Domains ◽  
Protein Domain ◽  
Semantic Meaning ◽  
Semantic Roles ◽  
Functional Roles ◽  
Eukaryotic Proteins

AbstractIn this paper, using word2vec, we demonstrate that proteins domains may have semantic “meaning” in the context of multi-domain proteins. Word2vec is a group of models which can be used to produce semantically meaningful embeddings of words or tokens in a vector space. In this work we treat multi-domain proteins as “sentences” where domain identifiers are tokens which may be considered as “words”. Using all Interpro (Finn, Attwood et al. 2017) eukaryotic proteins as a corpus of “sentences” we demonstrate that Word2vec creates functionally meaningful embeddings of protein domains. We additionally show how this can be applied to identifying the putative functional roles for Pfam (Finn, Coggill et al. 2016) Domains of Unknown Function.

Functional roles of protein domains on rice α-amylase activity

1997 ◽  
Vol 47 (4) ◽  
pp. 364-367 ◽  
Author(s):  
M. Terashima ◽  
M. Hosono ◽  
S. Katoh
Keyword(s):  
Amylase Activity ◽  
Protein Domains ◽  
Functional Roles

scholarly journals Alternative Splicing: Recent Insights into Mechanisms and Functional Roles

Cells ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 2327
Author(s):  
Claudia Ghigna ◽  
Maria Paola Paronetto
Keyword(s):  
Alternative Splicing ◽  
Human Cells ◽  
Protein Isoforms ◽  
Primary Transcript ◽  
Functional Roles ◽  
Multiple Protein

Alternative splicing generates multiple protein isoforms from one primary transcript and represents one of the major drivers of proteomic diversity in human cells [...]

scholarly journals A new generation of recombinant polypeptides combines multiple protein domains for effective antimicrobial activity

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Ramon Roca-Pinilla ◽  
Adrià López-Cano ◽  
Cristina Saubi ◽  
Elena Garcia-Fruitós ◽  
Anna Arís
Keyword(s):  
Antimicrobial Activity ◽  
Protein Domains ◽  
Multiple Protein ◽  
Recombinant Polypeptides ◽  
New Generation
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