N-tert-Butyl-N′-[5-cyano-2-(4-methylphenoxy)phenylsulfonyl]urea, a new TXA2receptor antagonist
2013 ◽
Vol 69
(8)
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pp. 901-903
Keyword(s):
The title compound, C19H21N3O4S, crystallizes in the space groupP2/cwith two molecules in the asymmetric unit. The conformation of both molecules is very similar and is mainly determined by an intramolecular N—H...O hydrogen bond between a urea N atom and a sulfonyl O atom. The O and second N atom of the urea groups are involved in dimer formationviaN—H...O hydrogen bonds. The intramolecular hydrogen-bonding motif and conformation of the C—SO2—NH(C=O)—NH—C fragment are explored and compared using the Cambridge Structural Database and theoretical calculations. The crystal packing is characterized by π–π stacking between the 5-cyanobenzene rings.
2013 ◽
Vol 9
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pp. 1127-1134
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2013 ◽
Vol 69
(11)
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pp. o1698-o1698
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Keyword(s):
1996 ◽
Vol 9
(5)
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pp. 255-261
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2002 ◽
Vol 4
(15)
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pp. 3843-3848
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1992 ◽
Vol 114
(27)
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pp. 10869-10873
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2020 ◽
Vol 76
(3)
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pp. 461-465