scholarly journals DeepGly: A Deep Learning Framework With Recurrent and Convolutional Neural Networks to Identify Protein Glycation Sites From Imbalanced Data

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 142368-142378
Author(s):  
Jingui Chen ◽  
Runtao Yang ◽  
Chengjin Zhang ◽  
Lina Zhang ◽  
Qian Zhang
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Imbalanced Data ◽  
Protein Glycation ◽  
Learning Framework

scholarly journals Multi-Task Learning for Metaphor Detection with Graph Convolutional Neural Networks and Word Sense Disambiguation

2020 ◽  
Vol 34 (05) ◽  
pp. 8139-8146
Author(s):  
Duong Le ◽  
My Thai ◽  
Thien Nguyen
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Word Sense Disambiguation ◽  
Word Sense ◽  
Knowledge Resources ◽  
Useful Knowledge ◽  
Learning Framework ◽  
Task Learning ◽  
Sense Disambiguation

The current deep learning works on metaphor detection have only considered this task independently, ignoring the useful knowledge from the related tasks and knowledge resources. In this work, we introduce two novel mechanisms to improve the performance of the deep learning models for metaphor detection. The first mechanism employs graph convolutional neural networks (GCN) with dependency parse trees to directly connect the words of interest with their important context words for metaphor detection. The GCN networks in this work also present a novel control mechanism to filter the learned representation vectors to retain the most important information for metaphor detection. The second mechanism, on the other hand, features a multi-task learning framework that exploits the similarity between word sense disambiguation and metaphor detection to transfer the knowledge between the two tasks. The extensive experiments demonstrate the effectiveness of the proposed techniques, yielding the state-of-the-art performance over several datasets.

scholarly journals Dynamic Spatial-Temporal Graph Convolutional Neural Networks for Traffic Forecasting

2019 ◽  
Vol 33 ◽  
pp. 890-897 ◽  
Author(s):  
Zulong Diao ◽  
Xin Wang ◽  
Dafang Zhang ◽  
Yingru Liu ◽  
Kun Xie ◽  
...  
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Tensor Decomposition ◽  
Laplacian Matrix ◽  
Traffic Data ◽  
Theoretical Derivation ◽  
Traffic Forecasting ◽  
Learning Framework ◽  
Spatial Dependencies

Graph convolutional neural networks (GCNN) have become an increasingly active field of research. It models the spatial dependencies of nodes in a graph with a pre-defined Laplacian matrix based on node distances. However, in many application scenarios, spatial dependencies change over time, and the use of fixed Laplacian matrix cannot capture the change. To track the spatial dependencies among traffic data, we propose a dynamic spatio-temporal GCNN for accurate traffic forecasting. The core of our deep learning framework is the finding of the change of Laplacian matrix with a dynamic Laplacian matrix estimator. To enable timely learning with a low complexity, we creatively incorporate tensor decomposition into the deep learning framework, where real-time traffic data are decomposed into a global component that is stable and depends on long-term temporal-spatial traffic relationship and a local component that captures the traffic fluctuations. We propose a novel design to estimate the dynamic Laplacian matrix of the graph with above two components based on our theoretical derivation, and introduce our design basis. The forecasting performance is evaluated with two realtime traffic datasets. Experiment results demonstrate that our network can achieve up to 25% accuracy improvement.

scholarly journals Skin Diseases Prediction using Deep Learning Framework

2020 ◽  
Vol 8 (6) ◽  
pp. 4781-4784
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Real Time ◽  
Convolutional Neural Networks ◽  
Skin Diseases ◽  
Dermatological Diseases ◽  
Learning Framework ◽  
Computer Aided ◽  
High Level ◽  
Almost All

Dermatological diseases are found to induce a serious impact on the health of millions of people as everyone is affected by almost all types of skin disorders every year. Since the human analysis of such diseases takes some time and effort, and current methods are only used to analyse singular types of skin diseases, there is a need for a more high-level computer-aided expertise in the analysis and diagnosis of multi-type skin diseases. This paper proposes an approach to use computer-aided techniques in deep learning neural networks such as Convolutional neural networks (CNN) and Residual Neural Networks (ResNet) to predict skin diseases real-time and thus provides more accuracy than other neural networks.

scholarly journals DeepEP: a deep learning framework for identifying essential proteins

2019 ◽  
Vol 20 (S16) ◽  
Author(s):  
Min Zeng ◽  
Min Li ◽  
Fang-Xiang Wu ◽  
Yaohang Li ◽  
Yi Pan
Keyword(s):  
Machine Learning ◽  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Sampling Method ◽  
Ppi Network ◽  
Essential Proteins ◽  
Learning Framework ◽  
Multi Scale ◽  
Topological Features

Abstract Background Essential proteins are crucial for cellular life and thus, identification of essential proteins is an important topic and a challenging problem for researchers. Recently lots of computational approaches have been proposed to handle this problem. However, traditional centrality methods cannot fully represent the topological features of biological networks. In addition, identifying essential proteins is an imbalanced learning problem; but few current shallow machine learning-based methods are designed to handle the imbalanced characteristics. Results We develop DeepEP based on a deep learning framework that uses the node2vec technique, multi-scale convolutional neural networks and a sampling technique to identify essential proteins. In DeepEP, the node2vec technique is applied to automatically learn topological and semantic features for each protein in protein-protein interaction (PPI) network. Gene expression profiles are treated as images and multi-scale convolutional neural networks are applied to extract their patterns. In addition, DeepEP uses a sampling method to alleviate the imbalanced characteristics. The sampling method samples the same number of the majority and minority samples in a training epoch, which is not biased to any class in training process. The experimental results show that DeepEP outperforms traditional centrality methods. Moreover, DeepEP is better than shallow machine learning-based methods. Detailed analyses show that the dense vectors which are generated by node2vec technique contribute a lot to the improved performance. It is clear that the node2vec technique effectively captures the topological and semantic properties of PPI network. The sampling method also improves the performance of identifying essential proteins. Conclusion We demonstrate that DeepEP improves the prediction performance by integrating multiple deep learning techniques and a sampling method. DeepEP is more effective than existing methods.

scholarly journals Deep convolutional neural networks for cardiovascular vulnerable plaque detection

2019 ◽  
Vol 277 ◽  
pp. 02024 ◽  
Author(s):  
Lincan Li ◽  
Tong Jia ◽  
Tianqi Meng ◽  
Yizhe Liu
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Vulnerable Plaque ◽  
Recall Rate ◽  
Superior Performance ◽  
Learning Approaches ◽  
Deep Convolutional Neural Networks ◽  
Vulnerable Plaques ◽  
Plaque Detection

In this paper, an accurate two-stage deep learning method is proposed to detect vulnerable plaques in ultrasonic images of cardiovascular. Firstly, a Fully Convonutional Neural Network (FCN) named U-Net is used to segment the original Intravascular Optical Coherence Tomography (IVOCT) cardiovascular images. We experiment on different threshold values to find the best threshold for removing noise and background in the original images. Secondly, a modified Faster RCNN is adopted to do precise detection. The modified Faster R-CNN utilize six-scale anchors (122,162,322,642,1282,2562) instead of the conventional one scale or three scale approaches. First, we present three problems in cardiovascular vulnerable plaque diagnosis, then we demonstrate how our method solve these problems. The proposed method in this paper apply deep convolutional neural networks to the whole diagnostic procedure. Test results show the Recall rate, Precision rate, IoU (Intersection-over-Union) rate and Total score are 0.94, 0.885, 0.913 and 0.913 respectively, higher than the 1st team of CCCV2017 Cardiovascular OCT Vulnerable Plaque Detection Challenge. AP of the designed Faster RCNN is 83.4%, higher than conventional approaches which use one-scale or three-scale anchors. These results demonstrate the superior performance of our proposed method and the power of deep learning approaches in diagnose cardiovascular vulnerable plaques.

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