scholarly journals Deep convolutional neural networks for cardiovascular vulnerable plaque detection

2019 ◽  
Vol 277 ◽  
pp. 02024 ◽  
Author(s):  
Lincan Li ◽  
Tong Jia ◽  
Tianqi Meng ◽  
Yizhe Liu
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Vulnerable Plaque ◽  
Recall Rate ◽  
Superior Performance ◽  
Learning Approaches ◽  
Deep Convolutional Neural Networks ◽  
Vulnerable Plaques ◽  
Plaque Detection

In this paper, an accurate two-stage deep learning method is proposed to detect vulnerable plaques in ultrasonic images of cardiovascular. Firstly, a Fully Convonutional Neural Network (FCN) named U-Net is used to segment the original Intravascular Optical Coherence Tomography (IVOCT) cardiovascular images. We experiment on different threshold values to find the best threshold for removing noise and background in the original images. Secondly, a modified Faster RCNN is adopted to do precise detection. The modified Faster R-CNN utilize six-scale anchors (122,162,322,642,1282,2562) instead of the conventional one scale or three scale approaches. First, we present three problems in cardiovascular vulnerable plaque diagnosis, then we demonstrate how our method solve these problems. The proposed method in this paper apply deep convolutional neural networks to the whole diagnostic procedure. Test results show the Recall rate, Precision rate, IoU (Intersection-over-Union) rate and Total score are 0.94, 0.885, 0.913 and 0.913 respectively, higher than the 1st team of CCCV2017 Cardiovascular OCT Vulnerable Plaque Detection Challenge. AP of the designed Faster RCNN is 83.4%, higher than conventional approaches which use one-scale or three-scale anchors. These results demonstrate the superior performance of our proposed method and the power of deep learning approaches in diagnose cardiovascular vulnerable plaques.

scholarly journals Deep learning networks reflect cytoarchitectonic features used in brain mapping

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Kai Kiwitz ◽  
Christian Schiffer ◽  
Hannah Spitzer ◽  
Timo Dickscheid ◽  
Katrin Amunts
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Brain Mapping ◽  
Learning Approaches ◽  
Deep Convolutional Neural Networks ◽  
Promising Alternative ◽  
Cortical Areas ◽  
Cytoarchitectonic Mapping ◽  
Profile Approach

AbstractThe distribution of neurons in the cortex (cytoarchitecture) differs between cortical areas and constitutes the basis for structural maps of the human brain. Deep learning approaches provide a promising alternative to overcome throughput limitations of currently used cytoarchitectonic mapping methods, but typically lack insight as to what extent they follow cytoarchitectonic principles. We therefore investigated in how far the internal structure of deep convolutional neural networks trained for cytoarchitectonic brain mapping reflect traditional cytoarchitectonic features, and compared them to features of the current grey level index (GLI) profile approach. The networks consisted of a 10-block deep convolutional architecture trained to segment the primary and secondary visual cortex. Filter activations of the networks served to analyse resemblances to traditional cytoarchitectonic features and comparisons to the GLI profile approach. Our analysis revealed resemblances to cellular, laminar- as well as cortical area related cytoarchitectonic features. The networks learned filter activations that reflect the distinct cytoarchitecture of the segmented cortical areas with special regard to their laminar organization and compared well to statistical criteria of the GLI profile approach. These results confirm an incorporation of relevant cytoarchitectonic features in the deep convolutional neural networks and mark them as a valid support for high-throughput cytoarchitectonic mapping workflows.

scholarly journals Learning Cartographic Building Generalization with Deep Convolutional Neural Networks

2019 ◽  
Vol 8 (6) ◽  
pp. 258 ◽  
Author(s):  
Yu Feng ◽  
Frank Thiemann ◽  
Monika Sester
Keyword(s):  
Neural Networks ◽  
Computer Vision ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Physical Reality ◽  
Learning Approaches ◽  
Deep Convolutional Neural Networks ◽  
Generative Adversarial Network ◽  
Adversarial Network ◽  
Cartographic Generalization

Cartographic generalization is a problem, which poses interesting challenges to automation. Whereas plenty of algorithms have been developed for the different sub-problems of generalization (e.g., simplification, displacement, aggregation), there are still cases, which are not generalized adequately or in a satisfactory way. The main problem is the interplay between different operators. In those cases the human operator is the benchmark, who is able to design an aesthetic and correct representation of the physical reality. Deep learning methods have shown tremendous success for interpretation problems for which algorithmic methods have deficits. A prominent example is the classification and interpretation of images, where deep learning approaches outperform traditional computer vision methods. In both domains-computer vision and cartography-humans are able to produce good solutions. A prerequisite for the application of deep learning is the availability of many representative training examples for the situation to be learned. As this is given in cartography (there are many existing map series), the idea in this paper is to employ deep convolutional neural networks (DCNNs) for cartographic generalizations tasks, especially for the task of building generalization. Three network architectures, namely U-net, residual U-net and generative adversarial network (GAN), are evaluated both quantitatively and qualitatively in this paper. They are compared based on their performance on this task at target map scales 1:10,000, 1:15,000 and 1:25,000, respectively. The results indicate that deep learning models can successfully learn cartographic generalization operations in one single model in an implicit way. The residual U-net outperforms the others and achieved the best generalization performance.

scholarly journals Deep Malaria Parasite Detection in Thin Blood Smear Microscopic Images

2021 ◽  
Vol 11 (5) ◽  
pp. 2284
Author(s):  
Asma Maqsood ◽  
Muhammad Shahid Farid ◽  
Muhammad Hassan Khan ◽  
Marcin Grzegorzek
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Red Blood Cells ◽  
Convolutional Neural Networks ◽  
Blood Cells ◽  
Superior Performance ◽  
Learning Models ◽  
Infected Female ◽  
The World ◽  
Augmentation Techniques

Malaria is a disease activated by a type of microscopic parasite transmitted from infected female mosquito bites to humans. Malaria is a fatal disease that is endemic in many regions of the world. Quick diagnosis of this disease will be very valuable for patients, as traditional methods require tedious work for its detection. Recently, some automated methods have been proposed that exploit hand-crafted feature extraction techniques however, their accuracies are not reliable. Deep learning approaches modernize the world with their superior performance. Convolutional Neural Networks (CNN) are vastly scalable for image classification tasks that extract features through hidden layers of the model without any handcrafting. The detection of malaria-infected red blood cells from segmented microscopic blood images using convolutional neural networks can assist in quick diagnosis, and this will be useful for regions with fewer healthcare experts. The contributions of this paper are two-fold. First, we evaluate the performance of different existing deep learning models for efficient malaria detection. Second, we propose a customized CNN model that outperforms all observed deep learning models. It exploits the bilateral filtering and image augmentation techniques for highlighting features of red blood cells before training the model. Due to image augmentation techniques, the customized CNN model is generalized and avoids over-fitting. All experimental evaluations are performed on the benchmark NIH Malaria Dataset, and the results reveal that the proposed algorithm is 96.82% accurate in detecting malaria from the microscopic blood smears.

Online Estimation of Lithium-Ion Battery Capacity Using Deep Convolutional Neural Networks

2018 ◽  
Author(s):  
Sheng Shen ◽  
M. K. Sadoughi ◽  
Xiangyi Chen ◽  
Mingyi Hong ◽  
Chao Hu
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Lithium Ion ◽  
Relevance Vector Machine ◽  
Rechargeable Batteries ◽  
Li Ion Battery ◽  
Deep Convolutional Neural Networks ◽  
Battery Capacity ◽  
Li Ion

Over the past two decades, safety and reliability of lithium-ion (Li-ion) rechargeable batteries have been receiving a considerable amount of attention from both industry and academia. To guarantee safe and reliable operation of a Li-ion battery pack and build failure resilience in the pack, battery management systems (BMSs) should possess the capability to monitor, in real time, the state of health (SOH) of the individual cells in the pack. This paper presents a deep learning method, named deep convolutional neural networks, for cell-level SOH assessment based on the capacity, voltage, and current measurements during a charge cycle. The unique features of deep convolutional neural networks include the local connectivity and shared weights, which enable the model to estimate battery capacity accurately using the measurements during charge. To our knowledge, this is the first attempt to apply deep learning to online SOH assessment of Li-ion battery. 10-year daily cycling data from implantable Li-ion cells are used to verify the performance of the proposed method. Compared with traditional machine learning methods such as relevance vector machine and shallow neural networks, the proposed method is demonstrated to produce higher accuracy and robustness in capacity estimation.

scholarly journals Classification for Avian Malaria Parasite Plasmodium Gallinaceum Blood Stages by Using Deep Convolutional Neural Networks

2021 ◽  
Author(s):  
Veerayuth Kittichai ◽  
Morakot Kaewthamasorn ◽  
Suchansa Thanee ◽  
Rangsan Jomtarak ◽  
Kamonpob Klanboot ◽  
...  
Keyword(s):  
Neural Networks ◽  
Convolutional Neural Networks ◽  
Malaria Parasite ◽  
Avian Malaria ◽  
Superior Performance ◽  
Rapid Screening ◽  
Plasmodium Gallinaceum ◽  
Deep Convolutional Neural Networks ◽  
Avian Malaria Parasite

Abstract Background: The infections of an avian malaria parasite (Plasmodium gallinaceum) in domestic chickens presents a major threat to poultry industry because it cause economical loss in both quality and quantity of meat and egg productions. Deep learning algorithms have been developed to identify avian malaria infections and classify its blood stage development. Methods: In this study, four types of deep convolutional neural networks namely Darknet, Darknet19, darknet19_448x448 and Densenet 201 are used to classify P. gallinaceum blood stages. We randomly collected dataset of 10,548 single-cell images consisting of four parasite stages from ten-infected blood films stained by Giemsa. All images were confirmed by three well-trained examiners. Results: In the model-wise comparison, the four neural network models gave us high values in the mean average precision at least 95%. Darknet can reproduce a superior performance in classification of the P. gallinaceum development stages across any other model architectures. In addition, Darknet also has best performance in multiple class-wise classification, scoring the average values of greater than 99% in accuracy, specificity, sensitivity, precision, and F1-score.Conclusions: Therefore, Darknet model is more suitable in the classification of P. gallinaceum blood stages than the other three models. The result may contribute us to develop the rapid screening tool for further assist non-expert in filed study where is lack of specific instrument for avian malaria diagnostic.

scholarly journals MS2CNN: predicting MS/MS spectrum based on protein sequence using deep convolutional neural networks

BMC Genomics ◽  
2019 ◽  
Vol 20 (S9) ◽  
Author(s):  
Yang-Ming Lin ◽  
Ching-Tai Chen ◽  
Jia-Ming Chang
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Large Scale ◽  
Learning Algorithm ◽  
Pearson Correlation ◽  
Tandem Mass ◽  
Spectral Library ◽  
Deep Convolutional Neural Networks ◽  
Library Search

Abstract Background Tandem mass spectrometry allows biologists to identify and quantify protein samples in the form of digested peptide sequences. When performing peptide identification, spectral library search is more sensitive than traditional database search but is limited to peptides that have been previously identified. An accurate tandem mass spectrum prediction tool is thus crucial in expanding the peptide space and increasing the coverage of spectral library search. Results We propose MS2CNN, a non-linear regression model based on deep convolutional neural networks, a deep learning algorithm. The features for our model are amino acid composition, predicted secondary structure, and physical-chemical features such as isoelectric point, aromaticity, helicity, hydrophobicity, and basicity. MS2CNN was trained with five-fold cross validation on a three-way data split on the large-scale human HCD MS2 dataset of Orbitrap LC-MS/MS downloaded from the National Institute of Standards and Technology. It was then evaluated on a publicly available independent test dataset of human HeLa cell lysate from LC-MS experiments. On average, our model shows better cosine similarity and Pearson correlation coefficient (0.690 and 0.632) than MS2PIP (0.647 and 0.601) and is comparable with pDeep (0.692 and 0.642). Notably, for the more complex MS2 spectra of 3+ peptides, MS2PIP is significantly better than both MS2PIP and pDeep. Conclusions We showed that MS2CNN outperforms MS2PIP for 2+ and 3+ peptides and pDeep for 3+ peptides. This implies that MS2CNN, the proposed convolutional neural network model, generates highly accurate MS2 spectra for LC-MS/MS experiments using Orbitrap machines, which can be of great help in protein and peptide identifications. The results suggest that incorporating more data for deep learning model may improve performance.

scholarly journals Fusion High-Resolution Network for Diagnosing ChestX-ray Images

Electronics ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 190 ◽  
Author(s):  
Zhiwei Huang ◽  
Jinzhao Lin ◽  
Liming Xu ◽  
Huiqian Wang ◽  
Tong Bai ◽  
...  
Keyword(s):  
Neural Networks ◽  
Deep Learning ◽  
High Resolution ◽  
Convolutional Neural Networks ◽  
Characteristic Curve ◽  
Area Under The Curve ◽  
Disease Classification ◽  
Deep Convolutional Neural Networks ◽  
Learning Methods ◽  
Global And Local

The application of deep convolutional neural networks (CNN) in the field of medical image processing has attracted extensive attention and demonstrated remarkable progress. An increasing number of deep learning methods have been devoted to classifying ChestX-ray (CXR) images, and most of the existing deep learning methods are based on classic pretrained models, trained by global ChestX-ray images. In this paper, we are interested in diagnosing ChestX-ray images using our proposed Fusion High-Resolution Network (FHRNet). The FHRNet concatenates the global average pooling layers of the global and local feature extractors—it consists of three branch convolutional neural networks and is fine-tuned for thorax disease classification. Compared with the results of other available methods, our experimental results showed that the proposed model yields a better disease classification performance for the ChestX-ray 14 dataset, according to the receiver operating characteristic curve and area-under-the-curve score. An ablation study further confirmed the effectiveness of the global and local branch networks in improving the classification accuracy of thorax diseases.

scholarly journals Thermal-based early breast cancer detection using inception V3, inception V4 and modified inception MV4

2021 ◽  
Author(s):  
Mohammed Abdulla Salim Al Husaini ◽  
Mohamed Hadi Habaebi ◽  
Teddy Surya Gunawan ◽  
Md Rafiqul Islam ◽  
Elfatih A. A. Elsheikh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Networks ◽  
Early Stage ◽  
Computational Cost ◽  
Optimization Methods ◽  
Optimization Method ◽  
Deep Convolutional Neural Networks ◽  
Breast Thermography

AbstractBreast cancer is one of the most significant causes of death for women around the world. Breast thermography supported by deep convolutional neural networks is expected to contribute significantly to early detection and facilitate treatment at an early stage. The goal of this study is to investigate the behavior of different recent deep learning methods for identifying breast disorders. To evaluate our proposal, we built classifiers based on deep convolutional neural networks modelling inception V3, inception V4, and a modified version of the latter called inception MV4. MV4 was introduced to maintain the computational cost across all layers by making the resultant number of features and the number of pixel positions equal. DMR database was used for these deep learning models in classifying thermal images of healthy and sick patients. A set of epochs 3–30 were used in conjunction with learning rates 1 × 10–3, 1 × 10–4 and 1 × 10–5, Minibatch 10 and different optimization methods. The training results showed that inception V4 and MV4 with color images, a learning rate of 1 × 10–4, and SGDM optimization method, reached very high accuracy, verified through several experimental repetitions. With grayscale images, inception V3 outperforms V4 and MV4 by a considerable accuracy margin, for any optimization methods. In fact, the inception V3 (grayscale) performance is almost comparable to inception V4 and MV4 (color) performance but only after 20–30 epochs. inception MV4 achieved 7% faster classification response time compared to V4. The use of MV4 model is found to contribute to saving energy consumed and fluidity in arithmetic operations for the graphic processor. The results also indicate that increasing the number of layers may not necessarily be useful in improving the performance.

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