Aiming at the problems of noise sensitivity and unclear contour in existing MRI image segmentation algorithms, a segmentation method combining regularized P-M de-noising model and improved watershed algorithm is proposed. First, the brain MRI image is pre-processed to obtain a brain
nuclear image. Then, the brain nuclear image is de-noised by a regularized P-M model. After that, the image is preliminarily segmented by the traditional watershed algorithm to extract the features of each small region. Finally, the small regions are merged by Fuzzy Clustering with Spatial
Pattern (FCSP) to obtain the segmentation image with smooth edges. The experimental results show that the algorithm can accurately segment the gray matter (GM), white matter (WM) and cerebrospinal fluid (CSF) regions. The average AOM and ME of the segmentation results on the BrainWeb dataset
reached 0.93 and 0.04, respectively.
