Breast ultrasound examination is a routine, fast, and safe method for clinical diagnosis of breast tumors. In this paper, a classification method based on multi-features and support vector machines was proposed for breast tumor diagnosis. Multi-features are composed of characteristic features and deep learning features of breast tumor images. Initially, an improved level set algorithm was used to segment the lesion in breast ultrasound images, which provided an accurate calculation of characteristic features, such as orientation, edge indistinctness, characteristics of posterior shadowing region, and shape complexity. Simultaneously, we used transfer learning to construct a pretrained model as a feature extractor to extract the deep learning features of breast ultrasound images. Finally, the multi-features were fused and fed to support vector machine for the further classification of breast ultrasound images. The proposed model, when tested on unknown samples, provided a classification accuracy of 92.5% for cancerous and noncancerous tumors.
Use of Deep Learning to Develop and Analyze Computational Hematoxylin and Eosin Staining of Prostate Core Biopsy Images for Tumor Diagnosis
