With the background of optimal design study on main powerhouse of Power Plant, the finite element software ANSYS is adopted to control the overall structure's displacement. After the choice of structural form and loads bearing system, the static and dynamic characteristics of this boiler steel frame are analyzed in detail. And the structure's displacement response of this boiler steel frame will also be discussed under permanent load, wind load and seismic action. The structural displacement response causing by four wind load cases (front wind, back wind, left wind and right wind) is emphatically discussed and the dynamic characteristics and response spectrum analysis are also be studied. Results show that this main powerhouse owns good seismic performance and excellent lateral displacement resistance capacity because of the high structure stiffness. It shows that the horizontal displacement of the whole structure under all load cases can meet the requirements of the limit value, which demonstrates the feasibility of this structural program.