Inferring initial state of the ancestral network of cellular fate decision: a case study of phage lambda

Author(s):  
Yiyu Pang ◽  
Jie Liang
2021 ◽  
Vol 12 (4) ◽  
pp. 045010
Author(s):  
Balaji Rakesh ◽  
Nipun Sharma ◽  
Rupali Nagar ◽  
Vipul Dhongade ◽  
Krishna Daware ◽  
...  

Abstract Sensors function by interacting with an appropriate stimulus, undergo a change in property, which is then diagnosed by making some measurements. For any sensor, the type of interaction between analyte and sensor surface determines its overall performance. This article explores the philosophy in which primary measurements like response curves can hold information on the “type” of interaction occurring between analyte and sensing material. As case study, titanium oxide (TiO2) pellet sensors fabricated by sol-gel growth of TiO2 nanoparticles (as-grown and annealed) are investigated for humidity sensing at room temperature. The sensors display a very fast response in the 0%–30% relative humidity (%RH) range and return to their initial state without applying any external heat treatment. The response curves are analysed in view of adsorption processes guided by Langmuir isotherms. Correlation between sensor microstructure, adsorption processes and response curve is used to build the mechanistic understanding of the sensing process. The results bring out a unique correlation between sensor microstructure, interaction of analyte with sensing material and profile of response curves. Further, the synthesised sensors exhibit a linear response in the 0%–30% RH range making them suitable for low humidity environments like food packaging industry.


2014 ◽  
Vol 106 (2) ◽  
pp. 615a
Author(s):  
SoonGweon Hong ◽  
Luke Lee
Keyword(s):  

2020 ◽  
Vol 34 (05) ◽  
pp. 7151-7159
Author(s):  
Thorsten Engesser ◽  
Tim Miller

Epistemic planning can be used to achieve implicit coordination in cooperative multi-agent settings where knowledge and capabilities are distributed between the agents. In these scenarios, agents plan and act on their own without having to agree on a common plan or protocol beforehand. However, epistemic planning is undecidable in general. In this paper, we show how implicit coordination can be achieved in a simpler, propositional setting by using nondeterminism as a means to allow the agents to take the other agents' perspectives. We identify a decidable fragment of epistemic planning that allows for arbitrary initial state uncertainty and non-determinism, but where actions can never increase the uncertainty of the agents. We show that in this fragment, planning for implicit coordination can be reduced to a version of fully observable nondeterministic (FOND) planning and that it thus has the same computational complexity as FOND planning. We provide a small case study, modeling the problem of multi-agent path finding with destination uncertainty in FOND, to show that our approach can be successfully applied in practice.


2012 ◽  
Vol 524-527 ◽  
pp. 3578-3583
Author(s):  
Hui Leng ◽  
Hua Qing Zhao ◽  
Li Zhang ◽  
Zhong Wang ◽  
Jie Rong ◽  
...  

On the seventeenth National People's Congress of CPC, the strategic goal of the construction of ecological civilization was first proposed. The construction of ecological civilization is new requirement for our country to realize well-off society. From the meaning and nature of ecological civilization, this paper tries to establish an index system of ecological civilization in county administrative areas, which is composed by the environment, ecological economy, ecological community, ecological awareness and Eco-system and includes twenty-six representative indexes. At last this system is used combined with AHP method to evaluate the level of ecological civilization in Haian county Jiangsu province. The result shows that the integrated score of ecological civilization of Haian county in 2010 is 0.6373, indicating that the ecological civilization level is at the initial state. On the five sub-systems, the level of ecological awareness is poor and this is the major factor that limits the level of ecological civilization of Haian.


Author(s):  
Maxime Conjard ◽  
Henning Omre

Data assimilation in models representing spatio-temporal phenomena poses a challenge, particularly if the spatial histogram of the variable appears with multiple modes. The traditional Kalman model is based on a Gaussian initial distribution and Gauss-linear forward and observation models. This model is contained in the class of Gaussian distribution and is therefore analytically tractable. It is however unsuitable for representing multimodality. We define the selection Kalman model that is based on a selection-Gaussian initial distribution and Gauss-linear forward and observation models. The selection-Gaussian distribution can be seen as a generalization of the Gaussian distribution and may represent multimodality, skewness and peakedness. This selection Kalman model is contained in the class of selection-Gaussian distributions and therefore it is analytically tractable. An efficient recursive algorithm for assessing the selection Kalman model is specified. The synthetic case study of spatio-temporal inversion of an initial state, inspired by pollution monitoring, suggests that the use of the selection Kalman model offers significant improvements compared to the traditional Kalman model when reconstructing discontinuous initial states.


Author(s):  
Glenn Trommels

After 13 years of IT experience in private enterprise, taking over the City of Rockford’s IT Department proved to be a shocking experience. The state of the city’s IT organization, processes, technology, network security practices, customer service practices, and organizational relationships were all examples of industry “worst practices”. This case study documents the initial state of the IT Department as the author found it and the steps taken to turn it into a responsive, value-adding organization. The study examines all aspects of the process including:• Communication and relationship building with other city departments;• Taking ownership and responsibility for IT strategy and decision making;• Centralizing IT purchases;• Establishing hardware and software standards;• Establishing a centralized help desk;• Technology assessment and improvements; and• IT process improvements.


2020 ◽  
Author(s):  
Pirkka Ollinaho

<div>Probabilistic forecasts provide information on how predictions of the atmospheric evolution may differ from the best guess solution provided by a deterministic forecast. Ensemble prediction systems generate this information through assessing uncertainties in both the model initial state and the model itself. In order to open up ensemble prediction research for a wider research community, we have recreated all 50+1 operational ECMWF ensemble initial states for OpenIFS. The data set covers one year (December 2016 to November 2017) twice a day. A range of model resolutions are provided to cover different research needs (TL159, TL399 and TL639). The probabilistic skill of OpenIFS ensembles using these initial states is showcased. A case study of typhoon Damrey, which severely affected Vietnam in 2017, will also be presented.</div>


PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e103636 ◽  
Author(s):  
Matthew L. Robb ◽  
Vahid Shahrezaei

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