Adaptive control of infusion pump for Type-I diabetes control using a self-tuning regulator

Author(s):  
William Goh ◽  
Michel Pasquier ◽  
Chai Quek
1984 ◽  
Vol 31 (3) ◽  
pp. 721-734 ◽  
Author(s):  
William V. Tamborlane ◽  
C. Martin Press

Ophthalmology ◽  
1982 ◽  
Vol 89 (7) ◽  
pp. 735-747 ◽  
Author(s):  
James E. Puklin ◽  
William V. Tamborlane ◽  
Philip Felig ◽  
Myron Genel ◽  
Robert S. Sherwin

2005 ◽  
Vol 35 (2) ◽  
pp. 123-136 ◽  
Author(s):  
S. M. K. Tan ◽  
Z. Shafiee ◽  
L. L. Wu ◽  
A. M. Rizal ◽  
J. M. Rey

Objectives: To examine the association between ethnicity, depression, quality of life, and diabetic control in Malaysian adolescents and young adults with type I diabetes mellitus. Methods: Fifty-two outpatients with type I diabetes (mean age 15.5 years) who attended a Diabetes Clinic were included. The level of HbA1c was the measure of diabetes control used (better control defined as HbA1c < 10%). Other variables were measured through questionnaires (e.g., depressive symptoms, quality of life), computerized diagnostic interviews (major depression), and medical records (e.g., demographic, family circumstances, compliance with treatment). Results: Ethnic Chinese youth showed better diabetic control than Malays and Indians (mean HbA1c 9.1%, 10.3%, and 11.0% respectively). Young people with better diabetic control (HbA1c < 10%) were more likely to have better quality of life and less likely to live in problematic families. When the cut-off for diabetic control was stricter (HbA1c ≤ 8%), the young person's compliance was the main predictor of poor control. Family problems were also associated with poor control but to a lesser extent. The initial association between poorer diabetes control and depression became non-significant when quality of life was taken into account. Conclusions: There are ethnic differences in juvenile diabetic control in this Malaysian sample which need to be understood further. Previous findings of an association between quality of life and glycemic control were verified but different definitions of good control showed different associations with individual and environmental variables. Clinicians' awareness and early intervention for psychosocial problems (for example, inadequate family support) could improve diabetes control.


1982 ◽  
Vol 307 (9) ◽  
pp. 513-518 ◽  
Author(s):  
Robert S. Mecklenburg ◽  
James W. Benson ◽  
Nancy M. Becker ◽  
Patricia L. Brazel ◽  
Paul N. Fredlund ◽  
...  

Author(s):  
Nabila Hassan Ali Abdella

Self-care activities and control of blood sugar levels among children with type I diabetes have a positive impact on the quality of their lives. The aim of this study was to assess the quality of life, self-care activities, and diabetes control among school age children. A descriptive design was used in the conduction of this study. Setting: The study was carried out at the Health Insurance at El-Arab El-Shamla clinic at Port Said City. A random sample of 223 children was recruited from diabetes clinic. Tools of Data Collection, two tools were used to collect the necessary data to achieve the aim of the study in six months period. The study revealed that there were statistical positive correlation between children`s quality of life, diabetes control, and their self-care activities regarding diabetes. The study was concluded that there is a clear relationship between children's high quality of life, control of diabetes and self-care activities. This study recommended that education and counseling for diabetic children are required to minimize the complications emergence and improve their quality of life.


Author(s):  
T. A. Stewart ◽  
D. Liggitt ◽  
S. Pitts ◽  
L. Martin ◽  
M. Siegel ◽  
...  

Insulin-dependant (Type I) diabetes mellitus (IDDM) is a metabolic disorder resulting from the lack of endogenous insulin secretion. The disease is thought to result from the autoimmune mediated destruction of the insulin producing ß cells within the islets of Langerhans. The disease process is probably triggered by environmental agents, e.g. virus or chemical toxins on a background of genetic susceptibility associated with particular alleles within the major histocompatiblity complex (MHC). The relation between IDDM and the MHC locus has been reinforced by the demonstration of both class I and class II MHC proteins on the surface of ß cells from newly diagnosed patients as well as mounting evidence that IDDM has an autoimmune pathogenesis. In 1984, a series of observations were used to advance a hypothesis, in which it was suggested that aberrant expression of class II MHC molecules, perhaps induced by gamma-interferon (IFN γ) could present self antigens and initiate an autoimmune disease. We have tested some aspects of this model and demonstrated that expression of IFN γ by pancreatic ß cells can initiate an inflammatory destruction of both the islets and pancreas and does lead to IDDM.


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