The mechanical behavior of multi-cracks under compression has become a very important project in the field of fracture mechanics and rock mechanics. In this paper, based on the previous theoretical results of the failure criterion for brittle materials under compression, experiment study is implemented. The specimens are square plates and are made of cement, sand and water, and the cracks are made by using a very thin film (0.1 mm). The relations of material compressive strength versus crack spacing and the lateral confining stress are obtained from experimental results. The experimental results agree well with the failure criterion for brittle materials under compression, which indicates that the criterion is effective and applicable.