Modeling and Single-Pass Simulation of CMP Cache Capacity and Accessibility

Author(s):  
Xudong Shi ◽  
Feiqi Su ◽  
Jih-Kwon Peir ◽  
Ye Xia ◽  
Zhen Yang
Keyword(s):  
2011 ◽  
Vol 34 (3) ◽  
pp. 473-481
Author(s):  
Guo-Fu XIE ◽  
Wen-Cheng WANG
Keyword(s):  

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 124341-124350
Author(s):  
Ruichang Cheng ◽  
Xingdong Liang ◽  
Fubo Zhang ◽  
Qichang Guo ◽  
Longyong Chen
Keyword(s):  

2020 ◽  
Vol 86 (5) ◽  
Author(s):  
Y. Lin ◽  
J. C. Wright ◽  
S. J. Wukitch

Ion cyclotron range of frequencies (ICRF) heating will be the sole auxiliary heating method on SPARC for both full-field (Bt0 ~ 12 T) D–T operation and reduced field (Bt0 ~ 8 T) D–D operation. Using the fast wave at ~120 MHz, good wave penetration and strong single-pass absorption is expected for D–T(3He), D(3He), D(H) and 4He(H) heating scenarios. The dependences of wave absorption on ${k_\parallel }$ , 3He concentration, resonance location, antenna poloidal location and losses on alpha particles and ash have been studied. The antenna loading has been assessed by comparison with the Alcator C-Mod antennae. An antenna spectrum of ${k_\parallel }\sim 15\text{--}18\,{\textrm{m}^{ - 1}}$ is shown to be good for both core absorption and edge coupling. For the control of impurity sources, the antenna straps are rotated ~10° to be perpendicular to the B field and the straps can run with different power levels in order to optimize the antenna spectrum and to minimize the image current on the antenna frame. Combining the physics constraints with the SPARC port design, maintenance requirement and contingency against antenna failure during D–T operation, we plan to mount on the inner wall of the vacuum vessel a total of 12 4-strap antennae in 6 ports while keeping 3-strap antennae that are insertable and removable on port plugs as the backup option.


2021 ◽  
Vol 804 ◽  
pp. 140717
Author(s):  
Yuhua Li ◽  
Yaqing Jiang ◽  
Qiong Xu ◽  
Aibin Ma ◽  
Jinghua Jiang ◽  
...  

Author(s):  
S. Bettoni ◽  
P. Craievich ◽  
M. Pedrozzi ◽  
M. Schaer ◽  
L. Stingelin

2021 ◽  
Vol 9 (5) ◽  
pp. 1015
Author(s):  
Tianyu Zhang ◽  
Xin Gao ◽  
Dongqiang Wang ◽  
Jixue Zhao ◽  
Nan Zhang ◽  
...  

Cryptosporidium parvum is a globally recognized zoonotic parasite of medical and veterinary importance. This parasite mainly infects intestinal epithelial cells and causes mild to severe watery diarrhea that could be deadly in patients with weakened or defect immunity. However, its molecular interactions with hosts and pathogenesis, an important part in adaptation of parasitic lifestyle, remain poorly understood. Here we report the identification and characterization of a C. parvum T-cell immunomodulatory protein homolog (CpTIPH). CpTIPH is a 901-aa single-pass type I membrane protein encoded by cgd5_830 gene that also contains a short Vibrio, Colwellia, Bradyrhizobium and Shewanella (VCBS) repeat and relatively long integrin alpha (ITGA) N-terminus domain. Immunofluorescence assay confirmed the location of CpTIPH on the cell surface of C. parvum sporozoites. In congruence with the presence of VCBS repeat and ITGA domain, CpTIPH displayed high, nanomolar binding affinity to host cell surface (i.e., Kd(App) at 16.2 to 44.7 nM on fixed HCT-8 and CHO-K1 cells, respectively). The involvement of CpTIPH in the parasite invasion is partly supported by experiments showing that an anti-CpTIPH antibody could partially block the invasion of C. parvum sporozoites into host cells. These observations provide a strong basis for further investigation of the roles of CpTIPH in parasite-host cell interactions.


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